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DNA virus

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progressing in a loop around the circular genome is also common. Some dsDNA viruses use a strand displacement method whereby one strand is synthesized from a template strand, and a complementary strand is then synthesized from the prior synthesized strand, forming a dsDNA genome. Lastly, some dsDNA viruses are replicated as part of a process called
373:. A common trait among duplodnaviruses is that they cause latent infections without replication while still being able to replicate in the future. Tailed bacteriophages are ubiquitous worldwide, important in marine ecology, and the subject of much research. Herpesviruses are known to cause a variety of epithelial diseases, including 177:
dsDNA viruses make use of several mechanisms to replicate their genome. Bidirectional replication, in which two replication forks are established at a replication origin site and move in opposite directions of each other, is widely used. A rolling circle mechanism that produces linear strands while
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that bonds to and cleaves the positive strand, allowing a DNA polymerase to use the negative strand as a template for replication. Replication progresses in a loop around the genome by means of extending the 3'-end of the positive strand, displacing the prior positive strand, and the endonuclease
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contains dsDNA viruses that encode a major capsid protein (MCP) that has the HK97 fold. Viruses in the realm also share a number of other characteristics involving the capsid and capsid assembly, including an icosahedral capsid shape and a terminase enzyme that packages viral DNA into the capsid
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folded structure in which the jelly roll (JR) fold is perpendicular to the surface of the viral capsid. Many members also share a variety of other characteristics, including a minor capsid protein that has a single JR fold, an ATPase that packages the genome during capsid assembly, and a common
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and all other viruses descended from such viruses. The prototypical members of the realm are called CRESS-DNA viruses and have circular ssDNA genomes. ssDNA viruses with linear genomes are descended from them, and in turn some dsDNA viruses with circular genomes are descended from linear ssDNA
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at each end of the genome that repeatedly unfold and refold during replication to change the direction of DNA synthesis to move back and forth along the genome, producing numerous copies of the genome in a continuous process. Individual genomes are then excised from this molecule by the viral
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upon entering a host cell. mRNA is then synthesized from the double-stranded form. The double-stranded form of ssDNA viruses may be produced either directly after entry into a cell or as a consequence of replication of the viral genome. Eukaryotic ssDNA viruses are replicated in the nucleus.
150:(mRNA) synthesis and is often used alongside standard virus taxonomy, which is based on evolutionary history. DNA viruses constitute two Baltimore groups: Group I: double-stranded DNA viruses, and Group II: single-stranded DNA viruses. While Baltimore classification is chiefly based on 54:. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and those that have one strand of DNA in their genome, called single-stranded DNA (ssDNA) viruses. dsDNA viruses primarily belong to two 225:
The second Baltimore group of DNA viruses are those that have a single-stranded DNA genome. ssDNA viruses have the same manner of transcription as dsDNA viruses. However, because the genome is single-stranded, it is first made into a double-stranded form by a
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Kauffman KM, Hussain FA, Yang J, Arevalo P, Brown JM, Chang WK, VanInsberghe D, Elsherbini J, Sharma RS, Cutler MB, Kelly L, Polz MF (1 February 2018). "A Major Lineage of Non-Tailed dsDNA Viruses as Unrecognized Killers of Marine Bacteria".
296:, nor do the realms share common ancestry with each other. As such, each virus realm represents at least one instance of viruses coming into existence. Within each realm, viruses are grouped together based on shared characteristics that are 170:. Second, once the RNA polymerase is recruited, it uses the negative strand as a template for synthesizing mRNA strands. Third, the RNA polymerase terminates transcription upon reaching a specific signal, such as a 362:(LUCA) of cellular life. Its origins not known, nor whether it is monophyletic or polyphyletic. A characteristic feature is the HK97-fold found in the MCP of all members, which is found outside the realm only in 193:, in which case they have evolved or acquired their own means of executing transcription and replication. dsDNA viruses are also commonly divided between tailed dsDNA viruses, referring to members of the realm 76:, which also includes some dsDNA viruses. Additionally, many DNA viruses are unassigned to higher taxa. Reverse transcribing viruses, which have a DNA genome that is replicated through an RNA intermediate by a 271:
is the only ssDNA family whose members have negative sense genomes, which are circular. Parvoviruses, as previously mentioned, may package either the positive or negative sense strand into virions. Lastly,
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are ubiquitous worldwide and, like tailed bacteriophages, play an important role in marine ecology. Most identified eukaryotic DNA viruses belong to the realm. Notable disease-causing viruses in
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into a circular loop. The new ssDNA may be packaged into virions or replicated by a DNA polymerase to form a double-stranded form for transcription or continuation of the replication cycle.
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of mRNA, viruses in each Baltimore group also typically share their manner of replication. Viruses in a Baltimore group do not necessarily share genetic relation or morphology.
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The first Baltimore group of DNA viruses are those that have a double-stranded DNA genome. All dsDNA viruses have their mRNA synthesized in a three-step process. First, a
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The relation between caudoviruses and herpesviruses is also uncertain: they may share a common ancestor or herpesviruses may be a divergent clade from the realm
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in the realm likely emerged from recombination events that merged the DNA of these plasmids and complementary DNA encoding the capsid proteins of RNA viruses.
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Bernstein H, Bernstein C (5 July 1973). "Circular and branched circular concatenates as possible intermediates in bacteriophage T4 DNA replication".
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Gershon AA, Breuer J, Cohen JI, Cohrs RJ, Gershon MD, Gilden D, Grose C, Hambleton S, Kennedy PG, Oxman MN, Seward JF, Yamanishi K (2 July 2015).
1089:"Create a megataxonomic framework, filling all principal taxonomic ranks, for DNA viruses encoding vertical jelly roll-type major capsid proteins" 340:
during assembly. Two groups of viruses are included in the realm: tailed bacteriophages, which infect prokaryotes and are assigned to the order
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DNA viruses are ubiquitous worldwide, especially in marine environments where they form an important part of marine ecosystems, and infect both
1049:"Create a megataxonomic framework, filling all principal/primary taxonomic ranks, for dsDNA viruses encoding HK97-type major capsid proteins" 163: 2298: 2252: 2221: 2195: 288:(ICTV) oversees virus taxonomy and organizes viruses at the basal level at the rank of realm. Virus realms correspond to the rank of 1215: 234:
Most ssDNA viruses contain circular genomes that are replicated via rolling circle replication (RCR). ssDNA RCR is initiated by an
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Kukhanova MK, Korovina AN, Kochetkov SN (December 2014). "Human herpes simplex virus: life cycle and development of inhibitors".
189:, and as such are relatively dependent on host cell machinery for transcription and replication, and those that replicate in the 6824: 6419: 359: 2185: 6960: 6980: 6608: 1572:"Viruses and Nutrient Cycles in the Sea: Viruses play critical roles in the structure and function of aquatic food webs" 240: 6528: 6284: 4131: 491: 250: 1372: 5875: 5380: 4454: 409: 1515:"Defining a Core Genome for the Herpesvirales and Exploring their Evolutionary Relationship with the Caudovirales" 6829: 1843:"Multiple Origins of Prokaryotic and Eukaryotic Single-Stranded DNA Viruses From Bacterial and Archaeal Plasmids" 572: 259: 179: 1754:"Kaposi's sarcoma associated herpes virus (KSHV/HHV 8): epidemiology, molecular biology and tissue distribution" 6676: 6577: 6494: 2354: 265:
Nearly all ssDNA viruses have positive sense genomes, but a few exceptions and peculiarities exist. The family
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of two MCPs to have an MCP with two jelly roll folds instead of one. The single jelly roll (SJR) fold MCPs of
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ssDNA viruses are classified into one realm and include several families that are unassigned to a realm:
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binds to the DNA upstream of the site where transcription begins, allowing for the recruitment of a host
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dsDNA viruses are classified into three realms and include many taxa that are unassigned to a realm:
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Koonin EV, Dolja VV, Krupovic M, Varsani A, Wolf YI, Yutin N, Zerbini M, Kuhn JH (18 October 2019).
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Koonin EV, Dolja VV, Krupovic M, Varsani A, Wolf YI, Yutin N, Zerbini M, Kuhn JH (18 October 2019).
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Koonin EV, Dolja VV, Krupovic M, Varsani A, Wolf YI, Yutin N, Zerbini M, Kuhn JH (18 October 2019).
6871: 6713: 6669: 6625: 6363: 5707: 5561: 5340: 5088: 5081: 3901: 3099: 2717: 2703: 2661: 2574: 386: 322: 5799: 5750: 5700: 5679: 5130: 2640: 6921: 5519: 4592: 4585: 3658: 3293: 3279: 2871: 2304: 2258: 2033: 1685: 1593: 1403: 6916: 6620: 5815: 4774: 4649: 4628: 4521: 4177: 3835: 3477: 3040: 2633: 2560: 2294: 2248: 2217: 2191: 2161: 2085: 2025: 1981: 1880: 1783: 1734: 1677: 1642: 1552: 1469: 1395: 1350: 1288: 1211: 955: 727: 545: 218: 424:, a type of extra-chromosomal DNA molecule that self-replicates inside its host. The kingdom 6652: 6546: 6179: 5605: 5533: 5426: 5001: 4943: 4906: 4635: 4366: 4324: 4272: 4235: 4205: 4166: 4020: 3946: 3803: 3125: 3088: 3062: 3020: 2821: 2811: 2626: 2478: 2449: 2286: 2240: 2151: 2141: 2075: 2067: 2017: 1971: 1963: 1870: 1862: 1814:"Create a megataxonomic framework, filling all principal taxonomic ranks, for ssDNA viruses" 1773: 1765: 1724: 1716: 1669: 1632: 1624: 1583: 1542: 1534: 1459: 1449: 1387: 1340: 1330: 1278: 1270: 947: 739: 583:. Many varidnaviruses can become endogenized in their host's genome; a peculiar example are 297: 289: 182:
whereby a viral genome in a host cell's DNA is replicated to another part of a host genome.
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Varidnaviria is either monophyletic or polyphyletic and may predate the LUCA. The kingdom
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used for cellular life but differ in that viruses within a realm do not necessarily share
171: 1259:"The New Scope of Virus Taxonomy: Partitioning the Virosphere Into 15 Hierarchical Ranks" 2013: 1858: 1530: 1326: 6994: 6899: 6786: 6657: 6516: 6499: 6304: 6234: 6108: 6086: 6054: 6019: 5925: 5890: 5826: 5669: 5658: 5621: 5463: 5347: 5237: 5166: 5156: 4917: 4709: 4672: 4578: 4373: 3957: 3930: 3577: 3566: 3470: 3435: 3428: 3414: 3407: 3356: 3328: 3258: 3247: 3212: 2996: 2799: 2668: 2605: 2539: 2517: 2439: 2290: 2244: 2156: 2129: 2080: 2055: 1976: 1951: 1875: 1842: 1729: 1704: 1637: 1612: 1547: 1514: 1464: 1437: 1345: 1310: 1283: 1258: 721: 691: 673: 667: 655: 643: 635: 510: 486: 460: 374: 227: 167: 51: 6148: 1778: 1753: 575:. Poxviruses have been highly prominent in the history of modern medicine, especially 366:, a type of nanocompartment found in bacteria: this relation is not fully understood. 7004: 6939: 6904: 6747: 6737: 6708: 6341: 6334: 6076: 5971: 5957: 5785: 5778: 5757: 5598: 5547: 5540: 5404: 5300: 5278: 5251: 5227: 5187: 5144: 5109: 5102: 5074: 5060: 5053: 4954: 4890: 4861: 4840: 4819: 4808: 4788: 4720: 4542: 4511: 4500: 4478: 4345: 4212: 4198: 4188: 4155: 4079: 4031: 3974: 3967: 3814: 3714: 3588: 3502: 3484: 3463: 3449: 3349: 3286: 3236: 3158: 3136: 3109: 3072: 2974: 2941: 2789: 2767: 2567: 2550: 2528: 2506: 2428: 2417: 1407: 951: 779: 753: 733: 715: 685: 649: 630:
The following taxa that are unassigned to a realm exclusively contain dsDNA viruses:
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Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology
703: 697: 588: 537: 468: 459:. Eukaryotic monodnaviruses are associated with many diseases, and they include 439: 2237:
Viruses: Molecular Biology, Host Interactions and Applications to Biotechnology
1967: 1866: 1613:"A century of phage research: Bacteriophages and the shaping of modern biology" 1538: 1257:
International Committee on Taxonomy of Viruses Executive Committee (May 2020).
6858: 6853: 6806: 6799: 6794: 6779: 6774: 6615: 6550: 6299: 6241: 5836: 5792: 5686: 5447: 4256: 4246: 3998: 3598: 2925: 2675: 1673: 1391: 1274: 564: 445: 378: 363: 246: 131: 96: 1454: 544:
show a relation to a group of proteins that contain SJR folds, including the
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appear to have emerged on multiple occasions from archaeal and bacterial
382: 2071: 2021: 346:, and herpesviruses, which infect animals and are assigned to the order 239:
cleaves the positive strand again to create a standalone genome that is
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Weidner-Glunde M, Kruminis-Kaszkiel E, Savanagoudar M (February 2020).
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dsDNA viruses can be subdivided between those that replicate in the
1924: 1311:"Multiple origins of viral capsid proteins from cellular ancestors" 6449: 6441: 6259: 6221: 480: 455:
contains eukaryotic CRESS-DNA viruses and the atypical members of
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CRESS-DNA viruses include three kingdoms that infect prokaryotes:
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strand may be packaged into capsids, varying from virus to virus.
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system is used to group viruses together based on their manner of
39: 20: 1898: 70:, and ssDNA viruses are almost exclusively assigned to the realm 6955: 6647: 6188: 2233:"Virion Structure, Genome Organization, and Taxonomy of Viruses" 6152: 6016: 5887: 5377: 4451: 4128: 3528: 2379: 2327: 2103: 1841:
Kazlauskas D, Varsani A, Koonin EV, Krupovic M (31 July 2019).
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Andrade-Martínez JS, Moreno-Gallego JL, Reyes A (August 2019).
519:, whose members have MCPs with a single vertical JR fold, and 587:, which after infecting a host, can protect the host against 253:(RHR), which is similar to RCR. Parvovirus genomes have 201:, and tailless or non-tailed dsDNA viruses of the realm 495:, with the two jelly roll folds colored in red and blue 276:
package both the positive and negative linear strands.
525:, whose members have MCPs with two vertical JR folds. 103:. They appear to have multiple origins, as viruses in 6978: 802:
is unassigned to a realm but is a proposed member of
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contain linear ssDNA genomes that are replicated via
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Three DNA virus realms are recognized: 2281:. In Tennant, P.; Fermin, G.; Foster, J. (eds.). 2235:. In Tennant, P.; Fermin, G.; Foster, J. (eds.). 197:, usually the tailed bacteriophages of the order 1206:Kerr J, Cotmore S, Bloom ME (25 November 2005). 2049: 2047: 358:is a very ancient realm, perhaps predating the 2108:International Committee on Taxonomy of Viruses 1821:International Committee on Taxonomy of Viruses 1189: 1187: 1096:International Committee on Taxonomy of Viruses 1056:International Committee on Taxonomy of Viruses 286:International Committee on Taxonomy of Viruses 122:Prominent disease-causing DNA viruses include 6164: 2339: 2128:Meyer H, Ehmann R, Smith GL (February 2020). 1952:"ssDNA Viruses: Key Players in Global Virome" 111:on multiple occasions, though the origins of 8: 6279: 6267: 2285:. San Diego, CA: Elsevier. pp. 55–82. 2239:. San Diego, CA: Elsevier. pp. 35–46. 1304: 1302: 1174: 1172: 1170: 258:endonuclease. For parvoviruses, either the 6475: 6359: 6321: 6171: 6157: 6149: 6071: 6060: 6049: 6038: 6027: 6013: 5942: 5931: 5920: 5909: 5898: 5884: 5880: 5821: 5664: 5627: 5583: 5469: 5432: 5421: 5410: 5399: 5388: 5374: 5273: 5038: 5027: 4986: 4949: 4912: 4825: 4814: 4759: 4715: 4678: 4506: 4495: 4484: 4473: 4462: 4448: 4330: 4319: 4278: 4241: 4183: 4172: 4161: 4150: 4139: 4125: 4121: 4026: 4015: 4004: 3952: 3820: 3809: 3768: 3731: 3720: 3709: 3664: 3653: 3642: 3583: 3572: 3561: 3550: 3539: 3525: 3334: 3323: 3264: 3253: 3242: 3131: 3094: 3057: 3046: 2947: 2888: 2877: 2866: 2855: 2784: 2773: 2762: 2751: 2611: 2600: 2545: 2534: 2523: 2512: 2434: 2423: 2412: 2401: 2390: 2376: 2372: 2346: 2332: 2324: 1143: 1141: 1023: 1021: 16:Virus that has DNA as its genetic material 2187:Molecular and Cellular Biology of Viruses 2155: 2145: 2079: 1975: 1874: 1777: 1728: 1636: 1587: 1546: 1463: 1453: 1344: 1334: 1282: 532:is likely derived from the other kingdom 1950:Malathi VG, Renuka Devi P (March 2019). 1114: 1112: 1042: 1040: 1038: 1036: 6985: 2054:Krupovic M, Koonin EV (February 2015). 1807: 1805: 1803: 1801: 1799: 1797: 1366: 1364: 1309:Krupovic M, Koonin EV (21 March 2017). 1082: 1080: 1078: 1076: 1074: 1072: 816: 2130:"Smallpox in the Post-Eradication Era" 1570:Wilhelm SW, Suttle CA (October 1999). 408:of the HUH superfamily that initiates 404:contains ssDNA viruses that encode an 974:"DNA strand displacement replication" 7: 1417:from the original on 27 October 2020 2277:Rampersad, S.; Tennant, P. (2018). 1931:. Swiss Institute of Bioinformatics 1905:. Swiss Institute of Bioinformatics 1494:. Swiss Institute of Bioinformatics 1438:"Herpesviral Latency—Common Themes" 1238:. Swiss Institute of Bioinformatics 1155:. Swiss Institute of Bioinformatics 1126:. Swiss Institute of Bioinformatics 1006:. Swiss Institute of Bioinformatics 980:. Swiss Institute of Bioinformatics 919:. Swiss Institute of Bioinformatics 893:. Swiss Institute of Bioinformatics 843:. Swiss Institute of Bioinformatics 164:transcription preinitiation complex 2291:10.1016/B978-0-12-811257-1.00003-6 2245:10.1016/B978-0-12-811257-1.00002-4 1705:"Varicella zoster virus infection" 913:"dsDNA rolling circle replication" 80:, are classified into the kingdom 14: 1373:"The LUCA and its complex virome" 887:"dsDNA bidirectional replication" 6988: 2214:Principles of Molecular Virology 770:, all members except viruses in 467:, which cause many cancers, and 1210:. CRC Press. pp. 171–185. 837:"dsDNA templated transcription" 513:. Two kingdoms are recognized: 6825:Last universal common ancestor 6420:Defective interfering particle 2216:. Elsevier. pp. 122–127. 2104:"Virus Taxonomy: 2019 Release" 1193: 861: 360:last universal common ancestor 50:(DNA) that is replicated by a 1: 6961:Clonally transmissible cancer 6397:Satellite-like nucleic acids 1149:"Rolling hairpin replication" 952:10.1016/0022-2836(73)90443-9 823: 1178: 1000:"Replicative transposition" 873: 492:Pseudoalteromonas virus PM2 251:rolling hairpin replication 209:Single-stranded DNA viruses 158:Double-stranded DNA viruses 7032: 6517:Class II or DNA transposon 6512:Class I or retrotransposon 1968:10.1007/s13337-019-00519-4 1867:10.1038/s41467-019-11433-0 1539:10.1038/s41598-019-47742-z 410:rolling circle replication 260:positive or negative sense 6830:Earliest known life forms 6704:Repeated sequences in DNA 6026: 6012: 5897: 5883: 5387: 5373: 4461: 4447: 4138: 4124: 3538: 3524: 2389: 2375: 1674:10.1134/S0006297914130124 1392:10.1038/s41579-020-0408-x 1275:10.1038/s41564-020-0709-x 1027: 789:are ssDNA virus families. 573:African swine fever virus 180:replicative transposition 6677:Endogenous viral element 6495:Horizontal gene transfer 1611:Keen EC (January 2015). 1455:10.3390/pathogens9020125 1315:Proc Natl Acad Sci U S A 777:The unassigned families 595:Baltimore classification 144:Baltimore classification 138:Baltimore classification 6374:dsDNA satellite virus ( 1336:10.1073/pnas.1621061114 798:contain ssDNA genomes. 614:, members of the class 6932:Helper dependent virus 6248:Biological dark matter 1629:10.1002/bies.201400152 1120:"ssDNA Rolling circle" 792:Viruses in the family 496: 331: 326:Illustrated sample of 222: 31: 6692:Endogenous retrovirus 6665:Origin of replication 6381:ssDNA satellite virus 6371:ssRNA satellite virus 484: 325: 216: 78:reverse transcriptase 48:deoxyribonucleic acid 24: 6636:Secondary chromosome 6631:Extrachromosomal DNA 6507:Transposable element 2359:virus classification 2184:Lostroh, P. (2019). 1721:10.1038/nrdp.2015.16 6872:Model lipid bilayer 6714:Interspersed repeat 5341:Permutotetraviridae 3100:Orthopolintovirales 2575:Malacoherpesviridae 2231:Fermin, G. (2018). 2190:. Garland Science. 2072:10.1038/nrmicro3389 2022:10.1038/nature25474 2014:2018Natur.554..118K 1859:2019NatCo..10.3425K 1709:Nat Rev Dis Primers 1662:Biochemistry (Mosc) 1531:2019NatSR...911342A 1327:2017PNAS..114E2401K 1321:(12): E2401–E2410. 280:ICTV classification 6182:organic structures 3659:Malgrandaviricetes 3294:Sphaerolipoviridae 3280:Matshushitaviridae 2872:Nucleocytoviricota 1899:"Papillomaviridae" 1030:, pp. 122–127 774:are ssDNA viruses. 627:are dsDNA viruses. 620:are dsDNA viruses. 607:are dsDNA viruses. 555:Marine viruses in 497: 332: 223: 221:is an ssDNA virus. 32: 6976: 6975: 6917:Non-cellular life 6724: 6723: 6463: 6462: 6436: 6435: 6390:ssRNA satellite ( 6146: 6145: 6142: 6141: 6138: 6137: 6134: 6133: 6130: 6129: 6126: 6125: 6122: 6121: 6118: 6117: 6008: 6007: 6004: 6003: 6000: 5999: 5996: 5995: 5992: 5991: 5988: 5987: 5870: 5869: 5866: 5865: 5862: 5861: 5858: 5857: 5854: 5853: 5850: 5849: 5846: 5845: 5816:Yunchangviricetes 5809: 5808: 5652: 5651: 5615: 5614: 5571: 5570: 5457: 5456: 5369: 5368: 5365: 5364: 5361: 5360: 5357: 5356: 5324: 5323: 5320: 5319: 5261: 5260: 5015: 5014: 5011: 5010: 4974: 4973: 4937: 4936: 4900: 4899: 4802: 4801: 4798: 4797: 4775:Carmotetraviridae 4747: 4746: 4703: 4702: 4666: 4665: 4650:Gammaflexiviridae 4643:Deltaflexiviridae 4629:Alphaflexiviridae 4522:Alphatetraviridae 4443: 4442: 4439: 4438: 4435: 4434: 4431: 4430: 4387: 4386: 4383: 4382: 4307: 4306: 4303: 4302: 4266: 4265: 4229: 4228: 4178:Chrymotiviricetes 4111: 4110: 4107: 4106: 4103: 4102: 4063: 4062: 4059: 4058: 4055: 4054: 4051: 4050: 3992: 3991: 3988: 3987: 3984: 3983: 3940: 3939: 3836:Bacilladnaviridae 3797: 3796: 3793: 3792: 3756: 3755: 3697: 3696: 3693: 3692: 3689: 3688: 3630: 3629: 3626: 3625: 3622: 3621: 3520: 3519: 3516: 3515: 3512: 3511: 3478:Portogloboviridae 3391: 3390: 3315: 3314: 3311: 3310: 3307: 3306: 3303: 3302: 3230: 3229: 3226: 3225: 3222: 3221: 3119: 3118: 3082: 3081: 3041:Preplasmiviricota 3034: 3033: 3030: 3029: 2935: 2934: 2843: 2842: 2839: 2838: 2835: 2834: 2831: 2830: 2739: 2738: 2735: 2734: 2731: 2730: 2727: 2726: 2634:Autographiviridae 2588: 2587: 2584: 2583: 2561:Alloherpesviridae 2500: 2499: 2496: 2495: 2492: 2491: 2488: 2487: 2212:Cann, A. (2015). 2147:10.3390/v12020138 2060:Nat Rev Microbiol 2008:(7690): 118–122. 1770:10.1136/mp.50.1.4 1668:(13): 1635–1652. 1380:Nat Rev Microbiol 728:Portogloboviridae 546:Cupin superfamily 219:canine parvovirus 7023: 6993: 6992: 6984: 6653:Gene duplication 6476: 6472:self-replication 6360: 6322: 6180:Self-replicating 6173: 6166: 6159: 6150: 6072: 6061: 6050: 6039: 6028: 6020:dsDNA-RT viruses 6014: 5943: 5932: 5921: 5910: 5899: 5891:ssRNA-RT viruses 5885: 5881: 5822: 5665: 5633:Serpentovirales 5628: 5606:Orthomyxoviridae 5584: 5534:Peribunyaviridae 5470: 5433: 5427:Chunqiuviricetes 5422: 5411: 5400: 5389: 5381:(–)ssRNA viruses 5375: 5274: 5117:Nanghoshaviridae 5039: 5028: 5002:Botourmiaviridae 4987: 4950: 4944:Howeltoviricetes 4913: 4907:Amabiliviricetes 4826: 4815: 4760: 4716: 4679: 4636:Betaflexiviridae 4507: 4496: 4485: 4474: 4463: 4455:(+)ssRNA viruses 4449: 4367:Picobirnaviridae 4331: 4325:Duplopiviricetes 4320: 4279: 4273:Vidaverviricetes 4242: 4236:Resentoviricetes 4206:Megabirnaviridae 4184: 4173: 4167:Duplornaviricota 4162: 4151: 4140: 4126: 4122: 4027: 4021:Huolimaviricetes 4016: 4005: 3953: 3947:Repensiviricetes 3821: 3810: 3804:Cressdnaviricota 3769: 3732: 3721: 3710: 3665: 3654: 3643: 3584: 3573: 3562: 3551: 3540: 3526: 3335: 3324: 3265: 3254: 3243: 3132: 3126:Tectiliviricetes 3095: 3089:Polintoviricetes 3063:Priklausovirales 3058: 3047: 3021:Marseilleviridae 2948: 2889: 2878: 2867: 2856: 2822:Papillomaviridae 2812:Zurhausenvirales 2785: 2774: 2763: 2752: 2627:Ackermannviridae 2612: 2601: 2546: 2535: 2524: 2513: 2479:Tristromaviridae 2450:Lipothrixviridae 2435: 2424: 2413: 2402: 2391: 2377: 2373: 2348: 2341: 2334: 2325: 2319: 2317: 2315: 2273: 2271: 2269: 2227: 2208: 2206: 2204: 2170: 2169: 2159: 2149: 2125: 2119: 2118: 2116: 2114: 2100: 2094: 2093: 2083: 2051: 2042: 2041: 1996: 1990: 1989: 1979: 1947: 1941: 1940: 1938: 1936: 1925:"Polyomaviridae" 1921: 1915: 1914: 1912: 1910: 1895: 1889: 1888: 1878: 1838: 1832: 1831: 1829: 1827: 1818: 1809: 1792: 1791: 1781: 1749: 1743: 1742: 1732: 1700: 1694: 1693: 1657: 1651: 1650: 1640: 1608: 1602: 1601: 1591: 1567: 1561: 1560: 1550: 1510: 1504: 1503: 1501: 1499: 1484: 1478: 1477: 1467: 1457: 1433: 1427: 1426: 1424: 1422: 1416: 1377: 1368: 1359: 1358: 1348: 1338: 1306: 1297: 1296: 1286: 1254: 1248: 1247: 1245: 1243: 1228: 1222: 1221: 1203: 1197: 1196:, pp. 61–62 1191: 1182: 1181:, pp. 40–41 1176: 1165: 1164: 1162: 1160: 1145: 1136: 1135: 1133: 1131: 1116: 1107: 1106: 1104: 1102: 1093: 1084: 1067: 1066: 1064: 1062: 1053: 1044: 1031: 1025: 1016: 1015: 1013: 1011: 996: 990: 989: 987: 985: 970: 964: 963: 935: 929: 928: 926: 924: 909: 903: 902: 900: 898: 883: 877: 876:, pp. 36–40 871: 865: 859: 853: 852: 850: 848: 833: 827: 826:, pp. 11–13 821: 740:Tristromaviridae 461:papillomaviruses 387:Kaposi's sarcoma 298:highly conserved 128:papillomaviruses 119:are less clear. 7031: 7030: 7026: 7025: 7024: 7022: 7021: 7020: 7001: 7000: 6999: 6987: 6979: 6977: 6972: 6922:Synthetic virus 6910:Artificial cell 6883: 6811: 6720: 6609:RNA replication 6604:DNA replication 6592: 6583:Group II intron 6481: 6471: 6459: 6450:Mammalian prion 6432: 6408: 6387:dsRNA satellite 6384:ssDNA satellite 6354: 6347: 6316: 6309: 6254: 6183: 6177: 6147: 6114: 6092: 6066:Revtraviricetes 6022: 5984: 5937:Revtraviricetes 5893: 5842: 5805: 5772:Paramyxoviridae 5720:Mononegavirales 5713: 5694:Crepuscuviridae 5648: 5611: 5589:Articulavirales 5578:Insthoviricetes 5567: 5453: 5416:Negarnaviricota 5383: 5353: 5316: 5294: 5268:Stelpaviricetes 5257: 5221: 5216:Polycipiviridae 5209:Dicistroviridae 5150: 5033:Pisoniviricetes 5007: 4970: 4933: 4896: 4867: 4794: 4754:Tolucaviricetes 4743: 4699: 4684:Amarillovirales 4662: 4612: 4572:Closteroviridae 4555:Martellivirales 4548: 4490:Kitrinoviricota 4457: 4427: 4411:Polymycoviridae 4379: 4299: 4262: 4225: 4134: 4099: 4087:Finnlakeviridae 4047: 4042:Pleolipoviridae 3980: 3936: 3914: 3885: 3863: 3841: 3789: 3763:Quintoviricetes 3752: 3685: 3618: 3534: 3508: 3387: 3369: 3299: 3270:Halopanivirales 3218: 3196: 3174: 3152: 3115: 3078: 3052:Maveriviricetes 3026: 2990: 2968: 2963:Phycodnaviridae 2931: 2909: 2883:Pokkesviricetes 2827: 2805: 2779:Papovaviricetes 2723: 2690:Rountreeviridae 2580: 2484: 2462: 2385: 2362: 2352: 2322: 2313: 2311: 2301: 2276: 2267: 2265: 2255: 2230: 2224: 2211: 2202: 2200: 2198: 2183: 2179: 2174: 2173: 2127: 2126: 2122: 2112: 2110: 2102: 2101: 2097: 2053: 2052: 2045: 1998: 1997: 1993: 1949: 1948: 1944: 1934: 1932: 1923: 1922: 1918: 1908: 1906: 1897: 1896: 1892: 1840: 1839: 1835: 1825: 1823: 1816: 1811: 1810: 1795: 1751: 1750: 1746: 1702: 1701: 1697: 1659: 1658: 1654: 1610: 1609: 1605: 1589:10.2307/1313569 1582:(10): 781–788. 1569: 1568: 1564: 1512: 1511: 1507: 1497: 1495: 1488:"Virus latency" 1486: 1485: 1481: 1435: 1434: 1430: 1420: 1418: 1414: 1386:(11): 661–670. 1375: 1370: 1369: 1362: 1308: 1307: 1300: 1256: 1255: 1251: 1241: 1239: 1230: 1229: 1225: 1218: 1205: 1204: 1200: 1192: 1185: 1177: 1168: 1158: 1156: 1147: 1146: 1139: 1129: 1127: 1118: 1117: 1110: 1100: 1098: 1091: 1086: 1085: 1070: 1060: 1058: 1051: 1046: 1045: 1034: 1026: 1019: 1009: 1007: 998: 997: 993: 983: 981: 972: 971: 967: 937: 936: 932: 922: 920: 911: 910: 906: 896: 894: 885: 884: 880: 872: 868: 860: 856: 846: 844: 835: 834: 830: 822: 818: 813: 800:Finnlakeviridae 795:Finnlakeviridae 772:Papovaviricetes 623:All viruses in 617:Papovaviricetes 603:All viruses in 597: 579:, which caused 506:jelly roll fold 479: 397: 320: 294:common ancestry 282: 211: 172:polyadenylation 160: 140: 17: 12: 11: 5: 7029: 7027: 7019: 7018: 7013: 7003: 7002: 6998: 6997: 6974: 6973: 6971: 6970: 6965: 6964: 6963: 6958: 6948: 6942: 6936: 6935: 6934: 6929: 6919: 6914: 6913: 6912: 6907: 6897: 6891: 6889: 6885: 6884: 6882: 6881: 6880: 6879: 6874: 6866: 6861: 6856: 6851: 6845: 6844: 6843: 6832: 6827: 6821: 6819: 6813: 6812: 6810: 6809: 6804: 6803: 6802: 6797: 6789: 6787:Kappa organism 6784: 6783: 6782: 6777: 6772: 6767: 6762: 6752: 6751: 6750: 6745: 6734: 6732: 6726: 6725: 6722: 6721: 6719: 6718: 6717: 6716: 6711: 6701: 6700: 6699: 6694: 6689: 6684: 6674: 6673: 6672: 6662: 6661: 6660: 6658:Non-coding DNA 6655: 6650: 6640: 6639: 6638: 6633: 6628: 6623: 6613: 6612: 6611: 6600: 6598: 6594: 6593: 6591: 6590: 6585: 6580: 6578:Group I intron 6575: 6570: 6569: 6568: 6558: 6557: 6556: 6553: 6544: 6541: 6536: 6531: 6521: 6520: 6519: 6514: 6504: 6503: 6502: 6500:Genomic island 6497: 6486: 6484: 6480:Mobile genetic 6473: 6465: 6464: 6461: 6460: 6458: 6457: 6452: 6446: 6444: 6438: 6437: 6434: 6433: 6431: 6430: 6429: 6428: 6425: 6416: 6414: 6410: 6409: 6407: 6406: 6405: 6404: 6401: 6395: 6388: 6385: 6382: 6379: 6372: 6368: 6366: 6357: 6349: 6348: 6346: 6345: 6338: 6330: 6328: 6319: 6311: 6310: 6308: 6307: 6305:dsDNA-RT virus 6302: 6300:ssRNA-RT virus 6297: 6295:(−)ssRNA virus 6292: 6290:(+)ssRNA virus 6287: 6282: 6277: 6276: 6275: 6264: 6262: 6256: 6255: 6253: 6252: 6251: 6250: 6245: 6235:Incertae sedis 6231: 6230: 6229: 6224: 6219: 6214: 6204: 6199: 6193: 6191: 6185: 6184: 6178: 6176: 6175: 6168: 6161: 6153: 6144: 6143: 6140: 6139: 6136: 6135: 6132: 6131: 6128: 6127: 6124: 6123: 6120: 6119: 6116: 6115: 6113: 6112: 6109:Caulimoviridae 6104: 6102: 6094: 6093: 6091: 6090: 6087:Hepadnaviridae 6082: 6080: 6069: 6058: 6055:Artverviricota 6047: 6036: 6024: 6023: 6017: 6010: 6009: 6006: 6005: 6002: 6001: 5998: 5997: 5994: 5993: 5990: 5989: 5986: 5985: 5983: 5982: 5975: 5968: 5961: 5953: 5951: 5940: 5929: 5926:Artverviricota 5918: 5907: 5895: 5894: 5888: 5878: 5872: 5871: 5868: 5867: 5864: 5863: 5860: 5859: 5856: 5855: 5852: 5851: 5848: 5847: 5844: 5843: 5841: 5840: 5832: 5830: 5827:Goujianvirales 5819: 5811: 5810: 5807: 5806: 5804: 5803: 5796: 5789: 5782: 5775: 5768: 5761: 5754: 5747: 5740: 5733: 5725: 5723: 5715: 5714: 5712: 5711: 5704: 5697: 5690: 5683: 5675: 5673: 5670:Jingchuvirales 5662: 5659:Monjiviricetes 5654: 5653: 5650: 5649: 5647: 5646: 5638: 5636: 5625: 5622:Milneviricetes 5617: 5616: 5613: 5612: 5610: 5609: 5602: 5594: 5592: 5581: 5573: 5572: 5569: 5568: 5566: 5565: 5558: 5551: 5544: 5537: 5530: 5523: 5516: 5513:Leishbuviridae 5509: 5502: 5495: 5488: 5480: 5478: 5467: 5464:Ellioviricetes 5459: 5458: 5455: 5454: 5452: 5451: 5443: 5441: 5430: 5419: 5408: 5397: 5385: 5384: 5378: 5371: 5370: 5367: 5366: 5363: 5362: 5359: 5358: 5355: 5354: 5352: 5351: 5348:Sarthroviridae 5344: 5332: 5330: 5326: 5325: 5322: 5321: 5318: 5317: 5315: 5314: 5306: 5304: 5296: 5295: 5293: 5292: 5284: 5282: 5271: 5263: 5262: 5259: 5258: 5256: 5255: 5248: 5241: 5238:Alvernaviridae 5233: 5231: 5223: 5222: 5220: 5219: 5212: 5205: 5198: 5191: 5184: 5181:Solinviviridae 5177: 5170: 5167:Picornaviridae 5162: 5160: 5157:Picornavirales 5152: 5151: 5149: 5148: 5141: 5134: 5127: 5124:Nanhypoviridae 5120: 5113: 5106: 5099: 5096:Medioniviridae 5092: 5085: 5078: 5071: 5068:Cremegaviridae 5064: 5057: 5049: 5047: 5036: 5025: 5017: 5016: 5013: 5012: 5009: 5008: 5006: 5005: 4997: 4995: 4984: 4976: 4975: 4972: 4971: 4969: 4968: 4960: 4958: 4947: 4939: 4938: 4935: 4934: 4932: 4931: 4923: 4921: 4918:Wolframvirales 4910: 4902: 4901: 4898: 4897: 4895: 4894: 4887: 4879: 4877: 4869: 4868: 4866: 4865: 4858: 4851: 4844: 4836: 4834: 4823: 4812: 4804: 4803: 4800: 4799: 4796: 4795: 4793: 4792: 4785: 4778: 4770: 4768: 4757: 4749: 4748: 4745: 4744: 4742: 4741: 4738:Sinhaliviridae 4734: 4726: 4724: 4713: 4710:Magsaviricetes 4705: 4704: 4701: 4700: 4698: 4697: 4689: 4687: 4676: 4673:Flasuviricetes 4668: 4667: 4664: 4663: 4661: 4660: 4653: 4646: 4639: 4632: 4624: 4622: 4614: 4613: 4611: 4610: 4603: 4596: 4589: 4582: 4579:Endornaviridae 4575: 4568: 4560: 4558: 4550: 4549: 4547: 4546: 4539: 4532: 4525: 4517: 4515: 4504: 4493: 4482: 4471: 4459: 4458: 4452: 4445: 4444: 4441: 4440: 4437: 4436: 4433: 4432: 4429: 4428: 4426: 4425: 4422:Botybirnavirus 4414: 4407: 4395: 4393: 4389: 4388: 4385: 4384: 4381: 4380: 4378: 4377: 4374:Partitiviridae 4370: 4363: 4356: 4353:Curvulaviridae 4349: 4341: 4339: 4328: 4317: 4309: 4308: 4305: 4304: 4301: 4300: 4298: 4297: 4289: 4287: 4276: 4268: 4267: 4264: 4263: 4261: 4260: 4252: 4250: 4239: 4231: 4230: 4227: 4226: 4224: 4223: 4216: 4209: 4202: 4194: 4192: 4181: 4170: 4159: 4148: 4136: 4135: 4129: 4119: 4113: 4112: 4109: 4108: 4105: 4104: 4101: 4100: 4098: 4097: 4090: 4083: 4071: 4069: 4065: 4064: 4061: 4060: 4057: 4056: 4053: 4052: 4049: 4048: 4046: 4045: 4037: 4035: 4024: 4013: 4002: 3994: 3993: 3990: 3989: 3986: 3985: 3982: 3981: 3979: 3978: 3971: 3963: 3961: 3958:Geplafuvirales 3950: 3942: 3941: 3938: 3937: 3935: 3934: 3931:Redondoviridae 3926: 3924: 3916: 3915: 3913: 3912: 3905: 3897: 3895: 3887: 3886: 3884: 3883: 3875: 3873: 3865: 3864: 3862: 3861: 3853: 3851: 3843: 3842: 3840: 3839: 3831: 3829: 3818: 3807: 3799: 3798: 3795: 3794: 3791: 3790: 3788: 3787: 3779: 3777: 3766: 3758: 3757: 3754: 3753: 3751: 3750: 3742: 3740: 3729: 3718: 3707: 3699: 3698: 3695: 3694: 3691: 3690: 3687: 3686: 3684: 3683: 3675: 3673: 3662: 3651: 3640: 3632: 3631: 3628: 3627: 3624: 3623: 3620: 3619: 3617: 3616: 3613:Plectroviridae 3609: 3606:Paulinoviridae 3602: 3594: 3592: 3581: 3578:Faserviricetes 3570: 3567:Hofneiviricota 3559: 3548: 3536: 3535: 3529: 3522: 3521: 3518: 3517: 3514: 3513: 3510: 3509: 3507: 3506: 3499: 3488: 3481: 3474: 3471:Polydnaviridae 3467: 3460: 3453: 3446: 3439: 3436:Globuloviridae 3432: 3429:Fuselloviridae 3425: 3418: 3415:Bicaudaviridae 3411: 3408:Ampullaviridae 3399: 3397: 3393: 3392: 3389: 3388: 3386: 3385: 3377: 3375: 3371: 3370: 3368: 3367: 3360: 3357:Hytrosaviridae 3353: 3345: 3343: 3332: 3329:Naldaviricetes 3321: 3317: 3316: 3313: 3312: 3309: 3308: 3305: 3304: 3301: 3300: 3298: 3297: 3290: 3283: 3275: 3273: 3262: 3259:Laserviricetes 3251: 3248:Dividoviricota 3240: 3232: 3231: 3228: 3227: 3224: 3223: 3220: 3219: 3217: 3216: 3213:Corticoviridae 3208: 3206: 3198: 3197: 3195: 3194: 3186: 3184: 3176: 3175: 3173: 3172: 3164: 3162: 3154: 3153: 3151: 3150: 3142: 3140: 3129: 3121: 3120: 3117: 3116: 3114: 3113: 3105: 3103: 3092: 3084: 3083: 3080: 3079: 3077: 3076: 3068: 3066: 3055: 3044: 3036: 3035: 3032: 3031: 3028: 3027: 3025: 3024: 3017: 3010: 3002: 3000: 2997:Pimascovirales 2992: 2991: 2989: 2988: 2980: 2978: 2970: 2969: 2967: 2966: 2958: 2956: 2945: 2937: 2936: 2933: 2932: 2930: 2929: 2921: 2919: 2911: 2910: 2908: 2907: 2899: 2897: 2886: 2875: 2864: 2853: 2845: 2844: 2841: 2840: 2837: 2836: 2833: 2832: 2829: 2828: 2826: 2825: 2817: 2815: 2807: 2806: 2804: 2803: 2800:Polyomaviridae 2795: 2793: 2782: 2771: 2760: 2749: 2741: 2740: 2737: 2736: 2733: 2732: 2729: 2728: 2725: 2724: 2722: 2721: 2714: 2707: 2700: 2697:Salasmaviridae 2693: 2686: 2679: 2672: 2669:Herelleviridae 2665: 2658: 2655:Drexlerviridae 2651: 2648:Demerecviridae 2644: 2637: 2630: 2622: 2620: 2609: 2606:Caudoviricetes 2598: 2590: 2589: 2586: 2585: 2582: 2581: 2579: 2578: 2571: 2564: 2556: 2554: 2543: 2540:Herviviricetes 2532: 2521: 2518:Heunggongvirae 2510: 2502: 2501: 2498: 2497: 2494: 2493: 2490: 2489: 2486: 2485: 2483: 2482: 2474: 2472: 2464: 2463: 2461: 2460: 2453: 2445: 2443: 2440:Ligamenvirales 2432: 2421: 2410: 2399: 2387: 2386: 2380: 2370: 2364: 2363: 2353: 2351: 2350: 2343: 2336: 2328: 2321: 2320: 2300:978-0128112571 2299: 2274: 2254:978-0128112571 2253: 2228: 2223:978-0128019559 2222: 2209: 2197:978-0429664304 2196: 2180: 2178: 2175: 2172: 2171: 2120: 2095: 2066:(2): 105–115. 2043: 1991: 1942: 1916: 1890: 1833: 1793: 1744: 1695: 1652: 1603: 1562: 1505: 1479: 1428: 1360: 1298: 1269:(5): 668–674. 1249: 1232:"Bidnaviridae" 1223: 1216: 1198: 1194:Rampersad 2018 1183: 1166: 1137: 1108: 1068: 1032: 1017: 991: 965: 946:(3): 355–361. 930: 904: 878: 866: 862:Rampersad 2018 854: 828: 815: 814: 812: 809: 808: 807: 790: 775: 760: 759: 758: 757: 743: 722:Polydnaviridae 692:Hytrosaviridae 674:Globuloviridae 668:Fuselloviridae 656:Bicaudaviridae 644:Ampullaviridae 639: 636:Ligamenvirales 628: 621: 608: 596: 593: 550:nucleoplasmins 511:DNA polymerase 489:of the MCP of 487:ribbon diagram 478: 473: 465:polyomaviruses 449:. The kingdom 396: 391: 375:herpes simplex 319: 314: 281: 278: 228:DNA polymerase 210: 207: 168:RNA polymerase 159: 156: 139: 136: 52:DNA polymerase 15: 13: 10: 9: 6: 4: 3: 2: 7028: 7017: 7014: 7012: 7009: 7008: 7006: 6996: 6991: 6986: 6982: 6969: 6966: 6962: 6959: 6957: 6954: 6953: 6952: 6949: 6947: 6943: 6941: 6940:Nanobacterium 6937: 6933: 6930: 6928: 6925: 6924: 6923: 6920: 6918: 6915: 6911: 6908: 6906: 6905:Cell division 6903: 6902: 6901: 6898: 6896: 6893: 6892: 6890: 6886: 6878: 6875: 6873: 6870: 6869: 6867: 6865: 6862: 6860: 6857: 6855: 6852: 6850: 6846: 6842: 6839: 6838: 6837: 6833: 6831: 6828: 6826: 6823: 6822: 6820: 6818: 6814: 6808: 6805: 6801: 6798: 6796: 6793: 6792: 6790: 6788: 6785: 6781: 6778: 6776: 6773: 6771: 6768: 6766: 6763: 6761: 6758: 6757: 6756: 6753: 6749: 6748:Hydrogenosome 6746: 6744: 6741: 6740: 6739: 6738:Mitochondrion 6736: 6735: 6733: 6731: 6730:Endosymbiosis 6727: 6715: 6712: 6710: 6709:Tandem repeat 6707: 6706: 6705: 6702: 6698: 6695: 6693: 6690: 6688: 6685: 6683: 6680: 6679: 6678: 6675: 6671: 6668: 6667: 6666: 6663: 6659: 6656: 6654: 6651: 6649: 6646: 6645: 6644: 6641: 6637: 6634: 6632: 6629: 6627: 6624: 6622: 6619: 6618: 6617: 6614: 6610: 6607: 6606: 6605: 6602: 6601: 6599: 6597:Other aspects 6595: 6589: 6586: 6584: 6581: 6579: 6576: 6574: 6571: 6567: 6564: 6563: 6562: 6559: 6554: 6552: 6548: 6545: 6542: 6540: 6537: 6535: 6532: 6530: 6527: 6526: 6525: 6522: 6518: 6515: 6513: 6510: 6509: 6508: 6505: 6501: 6498: 6496: 6493: 6492: 6491: 6488: 6487: 6485: 6483: 6477: 6474: 6470: 6466: 6456: 6453: 6451: 6448: 6447: 6445: 6443: 6439: 6426: 6423: 6422: 6421: 6418: 6417: 6415: 6411: 6402: 6399: 6398: 6396: 6393: 6389: 6386: 6383: 6380: 6377: 6373: 6370: 6369: 6367: 6365: 6361: 6358: 6356: 6350: 6344: 6343: 6342:Avsunviroidae 6339: 6337: 6336: 6335:Pospiviroidae 6332: 6331: 6329: 6327: 6323: 6320: 6318: 6312: 6306: 6303: 6301: 6298: 6296: 6293: 6291: 6288: 6286: 6283: 6281: 6278: 6274: 6271: 6270: 6269: 6266: 6265: 6263: 6261: 6257: 6249: 6246: 6244: 6243: 6239: 6238: 6237: 6236: 6232: 6228: 6225: 6223: 6220: 6218: 6215: 6213: 6210: 6209: 6208: 6205: 6203: 6200: 6198: 6195: 6194: 6192: 6190: 6189:Cellular life 6186: 6181: 6174: 6169: 6167: 6162: 6160: 6155: 6154: 6151: 6111: 6110: 6106: 6105: 6103: 6101: 6100: 6095: 6089: 6088: 6084: 6083: 6081: 6079: 6078: 6077:Blubervirales 6073: 6070: 6068: 6067: 6062: 6059: 6057: 6056: 6051: 6048: 6046: 6045: 6040: 6037: 6035: 6034: 6029: 6025: 6021: 6015: 6011: 5981: 5980: 5976: 5974: 5973: 5972:Pseudoviridae 5969: 5967: 5966: 5962: 5960: 5959: 5958:Belpaoviridae 5955: 5954: 5952: 5950: 5949: 5944: 5941: 5939: 5938: 5933: 5930: 5928: 5927: 5922: 5919: 5917: 5916: 5911: 5908: 5906: 5905: 5900: 5896: 5892: 5886: 5882: 5879: 5877: 5873: 5839: 5838: 5834: 5833: 5831: 5829: 5828: 5823: 5820: 5818: 5817: 5812: 5802: 5801: 5797: 5795: 5794: 5790: 5788: 5787: 5786:Rhabdoviridae 5783: 5781: 5780: 5779:Pneumoviridae 5776: 5774: 5773: 5769: 5767: 5766: 5762: 5760: 5759: 5758:Mymonaviridae 5755: 5753: 5752: 5748: 5746: 5745: 5741: 5739: 5738: 5734: 5732: 5731: 5727: 5726: 5724: 5722: 5721: 5716: 5710: 5709: 5708:Natareviridae 5705: 5703: 5702: 5698: 5696: 5695: 5691: 5689: 5688: 5684: 5682: 5681: 5677: 5676: 5674: 5672: 5671: 5666: 5663: 5661: 5660: 5655: 5645: 5644: 5640: 5639: 5637: 5635: 5634: 5629: 5626: 5624: 5623: 5618: 5608: 5607: 5603: 5601: 5600: 5599:Amnoonviridae 5596: 5595: 5593: 5591: 5590: 5585: 5582: 5580: 5579: 5574: 5564: 5563: 5562:Wupedeviridae 5559: 5557: 5556: 5552: 5550: 5549: 5548:Phenuiviridae 5545: 5543: 5542: 5541:Phasmaviridae 5538: 5536: 5535: 5531: 5529: 5528: 5524: 5522: 5521: 5517: 5515: 5514: 5510: 5508: 5507: 5503: 5501: 5500: 5496: 5494: 5493: 5489: 5487: 5486: 5482: 5481: 5479: 5477: 5476: 5471: 5468: 5466: 5465: 5460: 5450: 5449: 5445: 5444: 5442: 5440: 5439: 5434: 5431: 5429: 5428: 5423: 5420: 5418: 5417: 5412: 5409: 5407: 5406: 5405:Orthornavirae 5401: 5398: 5396: 5395: 5390: 5386: 5382: 5376: 5372: 5350: 5349: 5345: 5343: 5342: 5337: 5334: 5333: 5331: 5327: 5313: 5312: 5308: 5307: 5305: 5303: 5302: 5301:Stellavirales 5297: 5291: 5290: 5286: 5285: 5283: 5281: 5280: 5279:Patatavirales 5275: 5272: 5270: 5269: 5264: 5254: 5253: 5252:Solemoviridae 5249: 5247: 5246: 5242: 5240: 5239: 5235: 5234: 5232: 5230: 5229: 5228:Sobelivirales 5224: 5218: 5217: 5213: 5211: 5210: 5206: 5204: 5203: 5199: 5197: 5196: 5192: 5190: 5189: 5188:Caliciviridae 5185: 5183: 5182: 5178: 5176: 5175: 5171: 5169: 5168: 5164: 5163: 5161: 5159: 5158: 5153: 5147: 5146: 5145:Tobaniviridae 5142: 5140: 5139: 5135: 5133: 5132: 5128: 5126: 5125: 5121: 5119: 5118: 5114: 5112: 5111: 5110:Mononiviridae 5107: 5105: 5104: 5103:Mesoniviridae 5100: 5098: 5097: 5093: 5091: 5090: 5089:Gresnaviridae 5086: 5084: 5083: 5082:Euroniviridae 5079: 5077: 5076: 5075:Coronaviridae 5072: 5070: 5069: 5065: 5063: 5062: 5061:Arteriviridae 5058: 5056: 5055: 5054:Abyssoviridae 5051: 5050: 5048: 5046: 5045: 5040: 5037: 5035: 5034: 5029: 5026: 5024: 5023: 5018: 5004: 5003: 4999: 4998: 4996: 4994: 4993: 4988: 4985: 4983: 4982: 4977: 4967: 4966: 4962: 4961: 4959: 4957: 4956: 4955:Cryppavirales 4951: 4948: 4946: 4945: 4940: 4930: 4929: 4925: 4924: 4922: 4920: 4919: 4914: 4911: 4909: 4908: 4903: 4893: 4892: 4891:Steitzviridae 4888: 4886: 4885: 4881: 4880: 4878: 4876: 4875: 4870: 4864: 4863: 4862:Solspiviridae 4859: 4857: 4856: 4852: 4850: 4849: 4845: 4843: 4842: 4841:Atkinsviridae 4838: 4837: 4835: 4833: 4832: 4827: 4824: 4822: 4821: 4820:Leviviricetes 4816: 4813: 4811: 4810: 4809:Lenarviricota 4805: 4791: 4790: 4789:Tombusviridae 4786: 4784: 4783: 4779: 4777: 4776: 4772: 4771: 4769: 4767: 4766: 4761: 4758: 4756: 4755: 4750: 4740: 4739: 4735: 4733: 4732: 4728: 4727: 4725: 4723: 4722: 4721:Nodamuvirales 4717: 4714: 4712: 4711: 4706: 4696: 4695: 4691: 4690: 4688: 4686: 4685: 4680: 4677: 4675: 4674: 4669: 4659: 4658: 4654: 4652: 4651: 4647: 4645: 4644: 4640: 4638: 4637: 4633: 4631: 4630: 4626: 4625: 4623: 4621: 4620: 4615: 4609: 4608: 4604: 4602: 4601: 4597: 4595: 4594: 4590: 4588: 4587: 4583: 4581: 4580: 4576: 4574: 4573: 4569: 4567: 4566: 4562: 4561: 4559: 4557: 4556: 4551: 4545: 4544: 4543:Matonaviridae 4540: 4538: 4537: 4533: 4531: 4530: 4526: 4524: 4523: 4519: 4518: 4516: 4514: 4513: 4512:Hepelivirales 4508: 4505: 4503: 4502: 4501:Alsuviricetes 4497: 4494: 4492: 4491: 4486: 4483: 4481: 4480: 4479:Orthornavirae 4475: 4472: 4470: 4469: 4464: 4460: 4456: 4450: 4446: 4424: 4423: 4418: 4415: 4413: 4412: 4408: 4406: 4405: 4400: 4397: 4396: 4394: 4390: 4376: 4375: 4371: 4369: 4368: 4364: 4362: 4361: 4357: 4355: 4354: 4350: 4348: 4347: 4346:Amalgaviridae 4343: 4342: 4340: 4338: 4337: 4332: 4329: 4327: 4326: 4321: 4318: 4316: 4315: 4310: 4296: 4295: 4291: 4290: 4288: 4286: 4285: 4280: 4277: 4275: 4274: 4269: 4259: 4258: 4254: 4253: 4251: 4249: 4248: 4243: 4240: 4238: 4237: 4232: 4222: 4221: 4217: 4215: 4214: 4213:Quadriviridae 4210: 4208: 4207: 4203: 4201: 4200: 4199:Chrysoviridae 4196: 4195: 4193: 4191: 4190: 4189:Ghabrivirales 4185: 4182: 4180: 4179: 4174: 4171: 4169: 4168: 4163: 4160: 4158: 4157: 4156:Orthornavirae 4152: 4149: 4147: 4146: 4141: 4137: 4133: 4132:dsRNA viruses 4127: 4123: 4120: 4118: 4114: 4096: 4095: 4091: 4089: 4088: 4084: 4082: 4081: 4080:Anelloviridae 4076: 4073: 4072: 4070: 4066: 4044: 4043: 4039: 4038: 4036: 4034: 4033: 4032:Haloruvirales 4028: 4025: 4023: 4022: 4017: 4014: 4012: 4011: 4006: 4003: 4001: 4000: 3995: 3977: 3976: 3975:Genomoviridae 3972: 3970: 3969: 3968:Geminiviridae 3965: 3964: 3962: 3960: 3959: 3954: 3951: 3949: 3948: 3943: 3933: 3932: 3928: 3927: 3925: 3923: 3922: 3917: 3911: 3910: 3906: 3904: 3903: 3902:Metaxyviridae 3899: 3898: 3896: 3894: 3893: 3888: 3882: 3881: 3877: 3876: 3874: 3872: 3871: 3866: 3860: 3859: 3855: 3854: 3852: 3850: 3849: 3844: 3838: 3837: 3833: 3832: 3830: 3828: 3827: 3822: 3819: 3817: 3816: 3815:Arfiviricetes 3811: 3808: 3806: 3805: 3800: 3786: 3785: 3781: 3780: 3778: 3776: 3775: 3770: 3767: 3765: 3764: 3759: 3749: 3748: 3744: 3743: 3741: 3739: 3738: 3733: 3730: 3728: 3727: 3722: 3719: 3717: 3716: 3715:Cossaviricota 3711: 3708: 3706: 3705: 3700: 3682: 3681: 3677: 3676: 3674: 3672: 3671: 3666: 3663: 3661: 3660: 3655: 3652: 3650: 3649: 3644: 3641: 3639: 3638: 3633: 3615: 3614: 3610: 3608: 3607: 3603: 3601: 3600: 3596: 3595: 3593: 3591: 3590: 3589:Tubulavirales 3585: 3582: 3580: 3579: 3574: 3571: 3569: 3568: 3563: 3560: 3558: 3557: 3552: 3549: 3547: 3546: 3541: 3537: 3533: 3532:ssDNA viruses 3527: 3523: 3505: 3504: 3503:Rhizidiovirus 3500: 3498: 3497: 3492: 3489: 3487: 3486: 3485:Thaspiviridae 3482: 3480: 3479: 3475: 3473: 3472: 3468: 3466: 3465: 3464:Plasmaviridae 3461: 3459: 3458: 3454: 3452: 3451: 3450:Halspiviridae 3447: 3445: 3444: 3440: 3438: 3437: 3433: 3431: 3430: 3426: 3424: 3423: 3419: 3417: 3416: 3412: 3410: 3409: 3404: 3401: 3400: 3398: 3394: 3384: 3383: 3379: 3378: 3376: 3372: 3366: 3365: 3361: 3359: 3358: 3354: 3352: 3351: 3350:Baculoviridae 3347: 3346: 3344: 3342: 3341: 3336: 3333: 3331: 3330: 3325: 3322: 3318: 3296: 3295: 3291: 3289: 3288: 3287:Simuloviridae 3284: 3282: 3281: 3277: 3276: 3274: 3272: 3271: 3266: 3263: 3261: 3260: 3255: 3252: 3250: 3249: 3244: 3241: 3239: 3238: 3237:Helvetiavirae 3233: 3215: 3214: 3210: 3209: 3207: 3205: 3204: 3199: 3193: 3192: 3188: 3187: 3185: 3183: 3182: 3177: 3171: 3170: 3166: 3165: 3163: 3161: 3160: 3159:Kalamavirales 3155: 3149: 3148: 3144: 3143: 3141: 3139: 3138: 3137:Belfryvirales 3133: 3130: 3128: 3127: 3122: 3112: 3111: 3110:Adintoviridae 3107: 3106: 3104: 3102: 3101: 3096: 3093: 3091: 3090: 3085: 3075: 3074: 3073:Lavidaviridae 3070: 3069: 3067: 3065: 3064: 3059: 3056: 3054: 3053: 3048: 3045: 3043: 3042: 3037: 3023: 3022: 3018: 3016: 3015: 3011: 3009: 3008: 3004: 3003: 3001: 2999: 2998: 2993: 2987: 2986: 2982: 2981: 2979: 2977: 2976: 2975:Imitervirales 2971: 2965: 2964: 2960: 2959: 2957: 2955: 2954: 2949: 2946: 2944: 2943: 2942:Megaviricetes 2938: 2928: 2927: 2923: 2922: 2920: 2918: 2917: 2912: 2906: 2905: 2901: 2900: 2898: 2896: 2895: 2890: 2887: 2885: 2884: 2879: 2876: 2874: 2873: 2868: 2865: 2863: 2862: 2857: 2854: 2852: 2851: 2846: 2824: 2823: 2819: 2818: 2816: 2814: 2813: 2808: 2802: 2801: 2797: 2796: 2794: 2792: 2791: 2790:Sepolyvirales 2786: 2783: 2781: 2780: 2775: 2772: 2770: 2769: 2768:Cossaviricota 2764: 2761: 2759: 2758: 2753: 2750: 2748: 2747: 2742: 2720: 2719: 2718:Zobellviridae 2715: 2713: 2712: 2708: 2706: 2705: 2704:Schitoviridae 2701: 2699: 2698: 2694: 2692: 2691: 2687: 2685: 2684: 2680: 2678: 2677: 2673: 2671: 2670: 2666: 2664: 2663: 2662:Guelinviridae 2659: 2657: 2656: 2652: 2650: 2649: 2645: 2643: 2642: 2638: 2636: 2635: 2631: 2629: 2628: 2624: 2623: 2621: 2619: 2618: 2613: 2610: 2608: 2607: 2602: 2599: 2597: 2596: 2591: 2577: 2576: 2572: 2570: 2569: 2568:Herpesviridae 2565: 2563: 2562: 2558: 2557: 2555: 2553: 2552: 2551:Herpesvirales 2547: 2544: 2542: 2541: 2536: 2533: 2531: 2530: 2529:Peploviricota 2525: 2522: 2520: 2519: 2514: 2511: 2509: 2508: 2507:Duplodnaviria 2503: 2481: 2480: 2476: 2475: 2473: 2471: 2470: 2465: 2459: 2458: 2454: 2452: 2451: 2447: 2446: 2444: 2442: 2441: 2436: 2433: 2431: 2430: 2429:Tokiviricetes 2425: 2422: 2420: 2419: 2418:Taleaviricota 2414: 2411: 2409: 2408: 2403: 2400: 2398: 2397: 2392: 2388: 2384: 2383:dsDNA viruses 2378: 2374: 2371: 2369: 2365: 2360: 2356: 2349: 2344: 2342: 2337: 2335: 2330: 2329: 2326: 2310: 2306: 2302: 2296: 2292: 2288: 2284: 2280: 2275: 2264: 2260: 2256: 2250: 2246: 2242: 2238: 2234: 2229: 2225: 2219: 2215: 2210: 2199: 2193: 2189: 2188: 2182: 2181: 2176: 2167: 2163: 2158: 2153: 2148: 2143: 2139: 2135: 2131: 2124: 2121: 2109: 2105: 2099: 2096: 2091: 2087: 2082: 2077: 2073: 2069: 2065: 2061: 2057: 2050: 2048: 2044: 2039: 2035: 2031: 2027: 2023: 2019: 2015: 2011: 2007: 2003: 1995: 1992: 1987: 1983: 1978: 1973: 1969: 1965: 1961: 1957: 1953: 1946: 1943: 1930: 1926: 1920: 1917: 1904: 1900: 1894: 1891: 1886: 1882: 1877: 1872: 1868: 1864: 1860: 1856: 1852: 1848: 1844: 1837: 1834: 1822: 1815: 1808: 1806: 1804: 1802: 1800: 1798: 1794: 1789: 1785: 1780: 1775: 1771: 1767: 1763: 1759: 1755: 1748: 1745: 1740: 1736: 1731: 1726: 1722: 1718: 1714: 1710: 1706: 1699: 1696: 1691: 1687: 1683: 1679: 1675: 1671: 1667: 1663: 1656: 1653: 1648: 1644: 1639: 1634: 1630: 1626: 1622: 1618: 1614: 1607: 1604: 1599: 1595: 1590: 1585: 1581: 1577: 1573: 1566: 1563: 1558: 1554: 1549: 1544: 1540: 1536: 1532: 1528: 1524: 1520: 1516: 1509: 1506: 1493: 1489: 1483: 1480: 1475: 1471: 1466: 1461: 1456: 1451: 1447: 1443: 1439: 1432: 1429: 1413: 1409: 1405: 1401: 1397: 1393: 1389: 1385: 1381: 1374: 1367: 1365: 1361: 1356: 1352: 1347: 1342: 1337: 1332: 1328: 1324: 1320: 1316: 1312: 1305: 1303: 1299: 1294: 1290: 1285: 1280: 1276: 1272: 1268: 1264: 1263:Nat Microbiol 1260: 1253: 1250: 1237: 1233: 1227: 1224: 1219: 1217:9781444114782 1213: 1209: 1202: 1199: 1195: 1190: 1188: 1184: 1180: 1175: 1173: 1171: 1167: 1154: 1150: 1144: 1142: 1138: 1125: 1121: 1115: 1113: 1109: 1097: 1090: 1083: 1081: 1079: 1077: 1075: 1073: 1069: 1057: 1050: 1043: 1041: 1039: 1037: 1033: 1029: 1024: 1022: 1018: 1005: 1001: 995: 992: 979: 975: 969: 966: 961: 957: 953: 949: 945: 941: 934: 931: 918: 914: 908: 905: 892: 888: 882: 879: 875: 870: 867: 863: 858: 855: 842: 838: 832: 829: 825: 820: 817: 810: 805: 801: 797: 796: 791: 788: 787: 782: 781: 780:Anelloviridae 776: 773: 769: 765: 764: 763: 756: 755: 754:Rhizidiovirus 750: 749: 744: 742: 741: 736: 735: 734:Thaspiviridae 730: 729: 724: 723: 718: 717: 716:Plasmaviridae 712: 711: 706: 705: 700: 699: 694: 693: 688: 687: 686:Halspiviridae 682: 681: 676: 675: 670: 669: 664: 663: 658: 657: 652: 651: 650:Baculoviridae 646: 645: 640: 638: 637: 632: 631: 629: 626: 622: 619: 618: 613: 609: 606: 605:Duplodnaviria 602: 601: 600: 594: 592: 590: 589:giant viruses 586: 582: 578: 577:Variola virus 574: 570: 566: 562: 558: 553: 551: 547: 543: 542:Helvetiavirae 539: 535: 534:Helvetiavirae 531: 526: 524: 523: 518: 517: 516:Helvetiavirae 512: 507: 503: 502: 494: 493: 488: 483: 477: 474: 472: 470: 469:geminiviruses 466: 462: 458: 454: 453: 448: 447: 442: 441: 436: 435: 429: 427: 423: 419: 414: 411: 407: 403: 402: 395: 392: 390: 388: 384: 380: 376: 372: 367: 365: 361: 357: 356:Duplodnaviria 353: 351: 350: 349:Herpesvirales 345: 344: 338: 337: 336:Duplodnaviria 329: 328:Duplodnaviria 324: 318: 317:Duplodnaviria 315: 313: 311: 307: 303: 302:Duplodnaviria 299: 295: 291: 287: 279: 277: 275: 270: 269: 268:Anelloviridae 263: 261: 256: 255:hairpin loops 252: 248: 244: 242: 237: 232: 229: 220: 215: 208: 206: 204: 200: 196: 195:Duplodnaviria 192: 188: 183: 181: 175: 173: 169: 165: 157: 155: 153: 152:transcription 149: 148:messenger RNA 145: 137: 135: 133: 129: 125: 124:herpesviruses 120: 118: 114: 113:Duplodnaviria 110: 106: 102: 98: 93: 91: 90: 86:in the realm 85: 84: 79: 75: 74: 69: 68: 63: 62: 61:Duplodnaviria 57: 53: 49: 45: 41: 37: 29: 28: 27:Orthopoxvirus 23: 19: 6927:Viral vector 6770:Gerontoplast 6697:Transpoviron 6469:Nucleic acid 6455:Fungal prion 6353:Helper-virus 6340: 6333: 6240: 6233: 6107: 6099:Ortervirales 6097: 6085: 6075: 6064: 6053: 6044:Pararnavirae 6042: 6031: 5979:Retroviridae 5977: 5970: 5963: 5956: 5948:Ortervirales 5946: 5935: 5924: 5915:Pararnavirae 5913: 5902: 5835: 5825: 5814: 5800:Xinmoviridae 5798: 5791: 5784: 5777: 5770: 5765:Nyamiviridae 5763: 5756: 5751:Lispiviridae 5749: 5742: 5737:Bornaviridae 5735: 5728: 5718: 5706: 5701:Myriaviridae 5699: 5692: 5685: 5680:Aliusviridae 5678: 5668: 5657: 5641: 5631: 5620: 5604: 5597: 5587: 5576: 5560: 5555:Tospoviridae 5553: 5546: 5539: 5532: 5527:Nairoviridae 5525: 5518: 5511: 5506:Hantaviridae 5504: 5497: 5492:Arenaviridae 5490: 5485:Cruliviridae 5483: 5475:Bunyavirales 5473: 5462: 5446: 5436: 5425: 5414: 5403: 5392: 5346: 5339: 5335: 5311:Astroviridae 5309: 5299: 5287: 5277: 5266: 5250: 5245:Barnaviridae 5243: 5236: 5226: 5214: 5207: 5200: 5193: 5186: 5179: 5174:Marnaviridae 5172: 5165: 5155: 5143: 5136: 5131:Olifoviridae 5129: 5122: 5115: 5108: 5101: 5094: 5087: 5080: 5073: 5066: 5059: 5052: 5042: 5031: 5022:Pisuviricota 5020: 5000: 4992:Ourlivirales 4990: 4981:Miaviricetes 4979: 4963: 4953: 4942: 4928:Narnaviridae 4926: 4916: 4905: 4889: 4884:Blumeviridae 4882: 4874:Timlovirales 4872: 4860: 4855:Fiersviridae 4853: 4846: 4839: 4831:Norzivirales 4829: 4818: 4807: 4787: 4782:Luteoviridae 4780: 4773: 4763: 4752: 4736: 4729: 4719: 4708: 4694:Flaviviridae 4692: 4682: 4671: 4655: 4648: 4641: 4634: 4627: 4617: 4607:Virgaviridae 4605: 4598: 4591: 4584: 4577: 4570: 4565:Bromoviridae 4563: 4553: 4541: 4534: 4527: 4520: 4510: 4499: 4488: 4477: 4466: 4420: 4416: 4409: 4404:Birnaviridae 4402: 4398: 4372: 4365: 4358: 4351: 4344: 4336:Durnavirales 4334: 4323: 4314:Pisuviricota 4312: 4294:Cystoviridae 4292: 4284:Mindivirales 4282: 4271: 4255: 4245: 4234: 4218: 4211: 4204: 4197: 4187: 4176: 4165: 4154: 4143: 4094:Spiraviridae 4092: 4085: 4078: 4074: 4040: 4030: 4019: 4010:Saleviricota 4008: 3997: 3973: 3966: 3956: 3945: 3929: 3921:Recrevirales 3919: 3907: 3900: 3892:Mulpavirales 3890: 3880:Smacoviridae 3878: 3870:Cremevirales 3868: 3858:Circoviridae 3856: 3848:Cirlivirales 3846: 3834: 3826:Baphyvirales 3824: 3813: 3802: 3784:Parvoviridae 3782: 3774:Piccovirales 3772: 3761: 3747:Bidnaviridae 3745: 3735: 3726:Mouviricetes 3724: 3713: 3704:Shotokuvirae 3702: 3680:Microviridae 3678: 3670:Petitvirales 3668: 3657: 3648:Phixviricota 3646: 3635: 3611: 3604: 3597: 3587: 3576: 3565: 3554: 3545:Monodnaviria 3543: 3501: 3496:Dinodnavirus 3494: 3490: 3483: 3476: 3469: 3462: 3457:Ovaliviridae 3455: 3448: 3443:Guttaviridae 3441: 3434: 3427: 3422:Clavaviridae 3420: 3413: 3406: 3402: 3380: 3362: 3355: 3348: 3338: 3327: 3292: 3285: 3278: 3268: 3257: 3246: 3235: 3211: 3201: 3191:Adenoviridae 3189: 3179: 3169:Tectiviridae 3167: 3157: 3147:Turriviridae 3145: 3135: 3124: 3108: 3098: 3087: 3071: 3061: 3050: 3039: 3019: 3014:Iridoviridae 3012: 3005: 2995: 2983: 2973: 2961: 2951: 2940: 2924: 2916:Chitovirales 2914: 2904:Asfarviridae 2902: 2892: 2881: 2870: 2861:Bamfordvirae 2859: 2850:Varidnaviria 2848: 2820: 2810: 2798: 2788: 2777: 2766: 2757:Shotokuvirae 2755: 2746:Monodnaviria 2744: 2716: 2711:Siphoviridae 2709: 2702: 2695: 2688: 2681: 2674: 2667: 2660: 2653: 2646: 2641:Chaseviridae 2639: 2632: 2625: 2617:Caudovirales 2615: 2604: 2593: 2573: 2566: 2559: 2549: 2538: 2527: 2516: 2505: 2477: 2469:Primavirales 2467: 2455: 2448: 2438: 2427: 2416: 2405: 2394: 2367: 2312:. 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Retrieved 840: 831: 824:Lostroh 2019 819: 804:Varidnaviria 803: 799: 793: 786:Spiraviridae 784: 778: 771: 768:Monodnaviria 767: 761: 752: 748:Dinodnavirus 746: 738: 732: 726: 720: 714: 710:Ovaliviridae 708: 702: 696: 690: 684: 680:Guttaviridae 678: 672: 666: 662:Clavaviridae 660: 654: 648: 642: 634: 625:Varidnaviria 624: 615: 612:Monodnaviria 611: 604: 598: 576: 565:adenoviruses 561:Varidnaviria 560: 557:Varidnaviria 556: 554: 541: 533: 530:Bamfordvirae 529: 527: 522:Bamfordvirae 520: 514: 501:Varidnaviria 499: 498: 490: 476:Varidnaviria 475: 457:Monodnaviria 456: 452:Shotokuvirae 450: 444: 438: 432: 430: 426:Shotokuvirae 425: 418:Monodnaviria 417: 415: 406:endonuclease 401:Monodnaviria 399: 398: 394:Monodnaviria 393: 371:Caudovirales 370: 368: 355: 354: 347: 343:Caudovirales 341: 334: 333: 327: 316: 310:Varidnaviria 309: 306:Monodnaviria 305: 301: 283: 274:bidnaviruses 266: 264: 247:Parvoviruses 245: 236:endonuclease 233: 224: 203:Varidnaviria 202: 199:Caudovirales 198: 194: 187:cell nucleus 184: 176: 161: 141: 121: 117:Varidnaviria 116: 112: 105:Monodnaviria 104: 94: 87: 83:Pararnavirae 81: 73:Monodnaviria 71: 67:Varidnaviria 65: 59: 35: 33: 25: 18: 7011:DNA viruses 6951:Cancer cell 6817:Abiogenesis 6765:Chromoplast 6760:Chloroplast 6543:Degradative 6285:dsRNA virus 6280:ssDNA virus 6273:Giant virus 6268:dsDNA virus 5965:Metaviridae 5744:Filoviridae 5730:Artoviridae 5643:Aspiviridae 5520:Mypoviridae 5499:Fimoviridae 5289:Potyviridae 5202:Secoviridae 5195:Iflaviridae 5138:Roniviridae 5044:Nidovirales 4965:Mitoviridae 4848:Duinviridae 4765:Tolivirales 4731:Nodaviridae 4657:Tymoviridae 4619:Tymovirales 4600:Togaviridae 4593:Mayoviridae 4586:Kitaviridae 4536:Hepeviridae 4529:Benyviridae 4360:Hypoviridae 4220:Totiviridae 3909:Nanoviridae 3737:Polivirales 3637:Sangervirae 3382:Nimaviridae 3364:Nudiviridae 3340:Lefavirales 3203:Vinavirales 3181:Rowavirales 3007:Ascoviridae 2985:Mimiviridae 2953:Algavirales 2894:Asfuvirales 2683:Podoviridae 2595:Uroviricota 2457:Rudiviridae 2407:Zilligvirae 1962:(1): 3–12. 1853:(1): 3425. 1179:Fermin 2018 874:Fermin 2018 704:Nudiviridae 698:Nimaviridae 440:Sangervirae 416:Viruses in 364:encapsulins 97:prokaryotes 42:that has a 7005:Categories 6859:Proteinoid 6854:Coacervate 6807:Nitroplast 6800:Trophosome 6795:Bacteriome 6780:Apicoplast 6775:Leucoplast 6616:Chromosome 6534:Resistance 6242:Parakaryon 5837:Yueviridae 5793:Sunviridae 5687:Chuviridae 5448:Qinviridae 5329:Unassigned 4392:Unassigned 4257:Reoviridae 4247:Reovirales 4068:Unassigned 3999:Trapavirae 3599:Inoviridae 3396:Unassigned 3374:Unassigned 3320:Unassigned 2926:Poxviridae 2676:Myoviridae 2314:8 December 2268:8 December 2140:(2): 138. 1847:Nat Commun 1764:(1): 4–8. 1758:Mol Pathol 1623:(1): 6–9. 1576:BioScience 1448:(2): 125. 940:J Mol Biol 811:References 641:Families: 585:virophages 571:, and the 569:poxviruses 446:Trapavirae 379:chickenpox 132:poxviruses 101:eukaryotes 6868:Research 6849:Protocell 6588:Retrozyme 6547:Virulence 6529:Fertility 6376:Virophage 6364:Satellite 6355:dependent 6207:Eukaryota 6033:Riboviria 5904:Riboviria 5438:Muvirales 5394:Riboviria 4468:Riboviria 4145:Riboviria 3556:Loebvirae 2396:Adnaviria 2355:Baltimore 1929:ViralZone 1903:ViralZone 1715:: 15016. 1617:BioEssays 1492:ViralZone 1442:Pathogens 1408:220516514 1236:ViralZone 1153:ViralZone 1124:ViralZone 1028:Cann 2015 1004:ViralZone 978:ViralZone 917:ViralZone 891:ViralZone 841:ViralZone 434:Loebvirae 413:viruses. 191:cytoplasm 89:Riboviria 36:DNA virus 30:particles 6895:Organism 6888:See also 6864:Sulphobe 6841:Ribozyme 6836:RNA life 6743:Mitosome 6687:Prophage 6682:Provirus 6670:Replicon 6626:Circular 6573:Phagemid 6490:Mobilome 6482:elements 6392:Virusoid 6315:Subviral 6227:Protista 6212:Animalia 6197:Bacteria 5336:Families 4399:Families 4075:Families 3403:Families 2309:90170103 2263:89706800 2166:31991671 2090:25534808 2030:29364876 1986:31143827 1885:31366885 1739:27188665 1682:25749169 1647:25521633 1557:31383901 1474:32075270 1412:Archived 1400:32665595 1355:28265094 1293:32341570 745:Genera: 633:Orders: 581:smallpox 563:include 422:plasmids 383:shingles 109:plasmids 46:made of 6995:Viruses 6877:Jeewanu 6791:Organs 6755:Plastid 6555:Cryptic 6524:Plasmid 6222:Plantae 6202:Archaea 2157:7077202 2134:Viruses 2081:5898198 2038:4462007 2010:Bibcode 1977:6517461 1876:6668415 1855:Bibcode 1788:9208806 1730:5381807 1690:7414402 1638:4418462 1598:1313569 1548:6683198 1527:Bibcode 1519:Sci Rep 1465:7167855 1346:5373398 1323:Bibcode 1284:7186216 960:4580243 330:virions 241:ligated 6981:Portal 6968:Virome 6946:Nanobe 6643:Genome 6621:Linear 6566:Fosmid 6561:Cosmid 6326:Viroid 6317:agents 4417:Genera 3491:Genera 2307:  2297:  2261:  2251:  2220:  2194:  2164:  2154:  2088:  2078:  2036:  2028:  2002:Nature 1984:  1974:  1883:  1873:  1817:(docx) 1786:  1779:379571 1776:  1737:  1727:  1688:  1680:  1645:  1635:  1596:  1555:  1545:  1472:  1462:  1406:  1398:  1353:  1343:  1291:  1281:  1214:  1092:(docx) 1052:(docx) 958:  538:fusion 443:, and 385:, and 308:, and 290:domain 174:site. 130:, and 56:realms 44:genome 6442:Prion 6413:Other 6260:Virus 6217:Fungi 6018:VII: 4130:III: 2305:S2CID 2259:S2CID 2034:S2CID 1686:S2CID 1594:JSTOR 1415:(PDF) 1404:S2CID 1376:(PDF) 40:virus 38:is a 6956:HeLa 6900:Cell 6648:Gene 5889:VI: 4453:IV: 3530:II: 2316:2020 2295:ISBN 2270:2020 2249:ISBN 2218:ISBN 2205:2020 2192:ISBN 2162:PMID 2115:2020 2086:PMID 2026:PMID 1982:PMID 1937:2020 1911:2020 1881:PMID 1828:2020 1784:PMID 1735:PMID 1678:PMID 1643:PMID 1553:PMID 1500:2020 1470:PMID 1423:2020 1396:PMID 1351:PMID 1289:PMID 1244:2020 1212:ISBN 1161:2020 1132:2020 1103:2020 1063:2020 1012:2020 986:2020 956:PMID 925:2020 899:2020 849:2020 783:and 548:and 536:via 463:and 381:and 284:The 217:The 142:The 115:and 99:and 64:and 7016:DNA 6539:Col 6427:DNA 6424:RNA 6403:DNA 6400:RNA 5379:V: 4117:RNA 2381:I: 2368:DNA 2287:doi 2241:doi 2152:PMC 2142:doi 2076:PMC 2068:doi 2018:doi 2006:554 1972:PMC 1964:doi 1871:PMC 1863:doi 1774:PMC 1766:doi 1725:PMC 1717:doi 1670:doi 1633:PMC 1625:doi 1584:doi 1543:PMC 1535:doi 1460:PMC 1450:doi 1388:doi 1341:PMC 1331:doi 1319:114 1279:PMC 1271:doi 948:doi 766:In 610:In 7007:: 6551:Ti 5876:RT 5338:: 4419:: 4401:: 4077:: 3493:: 3405:: 2303:. 2293:. 2257:. 2247:. 2160:. 2150:. 2138:12 2136:. 2132:. 2106:. 2084:. 2074:. 2064:13 2062:. 2058:. 2046:^ 2032:. 2024:. 2016:. 2004:. 1980:. 1970:. 1960:30 1958:. 1954:. 1927:. 1901:. 1879:. 1869:. 1861:. 1851:10 1849:. 1845:. 1819:. 1796:^ 1782:. 1772:. 1762:50 1760:. 1756:. 1733:. 1723:. 1711:. 1707:. 1684:. 1676:. 1666:79 1664:. 1641:. 1631:. 1621:37 1619:. 1615:. 1592:. 1580:49 1578:. 1574:. 1551:. 1541:. 1533:. 1521:. 1517:. 1490:. 1468:. 1458:. 1444:. 1440:. 1410:. 1402:. 1394:. 1384:18 1382:. 1378:. 1363:^ 1349:. 1339:. 1329:. 1317:. 1313:. 1301:^ 1287:. 1277:. 1265:. 1261:. 1234:. 1186:^ 1169:^ 1151:. 1140:^ 1122:. 1111:^ 1094:. 1071:^ 1054:. 1035:^ 1020:^ 1002:. 976:. 954:. 944:77 942:. 915:. 889:. 839:. 751:, 737:, 731:, 725:, 719:, 713:, 707:, 701:, 695:, 689:, 683:, 677:, 671:, 665:, 659:, 653:, 647:, 591:. 567:, 552:. 485:A 437:, 389:. 377:, 352:. 312:. 304:, 205:. 134:. 126:, 92:. 58:: 34:A 6983:: 6944:? 6938:? 6847:† 6834:? 6549:/ 6394:) 6378:) 6172:e 6165:t 6158:v 2361:) 2357:( 2347:e 2340:t 2333:v 2318:. 2289:: 2272:. 2243:: 2226:. 2207:. 2168:. 2144:: 2117:. 2092:. 2070:: 2040:. 2020:: 2012:: 1988:. 1966:: 1939:. 1913:. 1887:. 1865:: 1857:: 1830:. 1790:. 1768:: 1741:. 1719:: 1713:1 1692:. 1672:: 1649:. 1627:: 1600:. 1586:: 1559:. 1537:: 1529:: 1523:9 1502:. 1476:. 1452:: 1446:9 1425:. 1390:: 1357:. 1333:: 1325:: 1295:. 1273:: 1267:5 1246:. 1220:. 1163:. 1134:. 1105:. 1065:. 1014:. 988:. 962:. 950:: 927:. 901:. 851:. 806:.

Index


Orthopoxvirus
virus
genome
deoxyribonucleic acid
DNA polymerase
realms
Duplodnaviria
Varidnaviria
Monodnaviria
reverse transcriptase
Pararnavirae
Riboviria
prokaryotes
eukaryotes
plasmids
herpesviruses
papillomaviruses
poxviruses
Baltimore classification
messenger RNA
transcription
transcription preinitiation complex
RNA polymerase
polyadenylation
replicative transposition
cell nucleus
cytoplasm

canine parvovirus

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