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105:– a tumor involving subcutaneous long bones – stating the common cause to be fibrovascular defect. However, the latter is distinguished from an osteofibrous dysplasia by the presence of soft tissue extension, intramedullary extension, periosteal reaction and presence of hyperchromic epithelial cells under the microscope.
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Osteofibrous dysplasia is treated with marginal resection with or without bone grafting, depending on the size of the lesion and the extent of bony involvement. However, due to the high rate of recurrence in skeletally immature individuals, this procedure is usually postponed until skeletal maturity.
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The tibia is the most commonly involved bone, accounting for 85% of cases. It is usually painless, although there may be localized pain or fracture, and presents as a localized firm swelling of the tibia in children less than two decades old (median age for males 10, females 13). Several authors
275:"A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the literature"
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condition with no known cause. It is considered a fibrovascular defect. Campanacci described this condition in two leg bones, the
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Campanacci M (August 1976). "Osteofibrous dysplasia of long bones a new clinical entity".
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Hatori M, Watanabe M, Hosaka M, Sasano H, Narita M, Kokubun S (2006).
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MRI of bone and soft tissue tumors and tumorlike lesions
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173:Juvenile active ossifying fibroma
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246:Steven P. Meyers (2008).
110:fibrous dysplasia of bone
90:fibrous dysplasia of bone
202:Ital J Orthop Traumatol
230:Osteofibrous Dysplasia
70:Osteofibrous dysplasia
33:Osteofibrous dysplasia
86:nonossifying fibroma
318:E-medicine overview
292:10.1620/tjem.209.53
114:immunohistochemical
397:Skeletal disorders
356:External resources
151:. You can help by
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18:Fibroma, ossifying
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118:osteonectin
38:Other names
386:Categories
252:. Thieme.
187:References
171:See also:
160:March 2023
365:eMedicine
178:Treatment
132:Diagnosis
49:Specialty
301:16636523
54:Oncology
346:D018214
214:1024109
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341:MeSH
297:PMID
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