235:
342:
223:
173:
48:
163:
There are three parts of the small intestine. The duodenum is the 1st section of small intestine and only about a foot long. The jejunum and ileum make up most of the small intestine. Most of the nutrients in food are absorbed into the bloodstream in these two parts. (American Cancer
Society, 2023)
109:
Small intestine cancer starts when cells in the small intestine start to grow out of control. The small intestine is the largest part of the gastrointestinal tract (GI tract), which processes food for energy and rids the body of solid waste. The small intestine is not as common as other cancers of
159:
The small intestine works by mixing food and gastric juices into a thick fluid in the stomach and then emptied into the small intestine. It then continues to break down and absorb the nutrients. Although it is referred to as the small intestine, it is the longest section of the GI tract being
251:
602:
587:
282:
Diet: Various research has suggested that diets high in red meat and salted or smoked foods may raise the risk of small intestine cancer.(Cleveland Clinic, 2022). A human prospective study observed a markedly elevated risk for
140:
Experts believe that small intestine cancer develops much like colorectal cancer. It first begins as a small growth on the inner lining of the intestine (polyp), which over time becomes cancer. (American Cancer
Society, 2023)
110:
the GI tract such as colon, rectal, stomach, and esophageal cancers in the United States. They account for fewer than 1 in 10 cancers in the GI tract, and fewer than 1 in 100 cancers overall. (American Cancer
Society, 2023)
275:
HIV/AIDS- treatments like radiation therapy may weaken your immune system and make you more susceptible to small intestine cancer. Drugs that suppress your immune system may also increase your risk.(Cleveland Clinic,
272:
Race: In the U.S., small intestine cancer is slightly more common among people who identify as
African Americans. Although lymphoma is more common among people who identify as white.(Cleveland Clinic, 2022)
341:
216:
Most small intestine cancers (especially adenocarcinomas) develop in the duodenum. Cancers developed in the duodenum are often found at the ampulla of Vater. (American Cancer
Society, 2023)
329:, which alters the flow of bile to the small intestine, increases the risk of small intestinal adenocarcinomas, and this risk declines with increasing distance from the common bile duct.
521:
Cross AJ, Leitzmann MF, Subar AF, Thompson FE, Hollenbeck AR, Schatzkin A. A prospective study of meat and fat intake in relation to small intestinal cancer. Cancer Res 2008;68:9274–9
234:
656:
212:
of the midgut-This is a type of neuroendocrine tumor (NET). They tend to be slow growing and are the most common type of small intestine tumor. (American Cancer
Society, 2023)
156:, the outlet of the common bile duct from which bile acids are released. This area is also closely associated with the pancreas, so they are treated as pancreatic cancer.
404:
Ross RK, Hartnett NM, Bernstein L, Henderson BE. Epidemiology of adenocarcinomas of the small intestine: is bile a small bowel carcinogen. Br J Cancer 1991;63:143–5
482:
Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C (March 2005). "Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling?".
887:
912:
317:
222:
649:
1137:
541:. American Cancer Society. Retrieved April 3, 2023, from https://www.cancer.org/cancer/small-intestine-cancer/about/what-is-key-statistics.html
997:
191:-This cancer begins in the gland cells that line the inside of the intestine. Adenocarcinomas account for about 1 in 3 small intestine cancers.
1186:
1142:
642:
530:
Lagergren J, Ye W, Ekbom A. Intestinal cancer after cholecystectomy: is bile involved in carcinogenesis. Gastroenterology 2001;121:542–7
199:
This type of cancer starts in connective tissues. The most common sarcoma in the intestine are gastrointestinal stromal tumors (GISTs)
749:
555:. Cancer Treatment Centers of America. Retrieved April 4, 2023, from https://www.cancercenter.com/cancer-types/intestinal-cancer
1207:
1045:
160:
approximately 20 feet long. The length of the small intestine comprises 75% of the length of the entire gastrointestinal tract
548:. Cleveland Clinic. Retrieved April 4, 2023, from https://my.clevelandclinic.org/health/articles/6225-small-intestine-cancer
172:
1147:
950:
907:
878:
313:
198:
194:
858:
152:
even though this location comprises only 4% of the length of the small intestine. These adenomas occur mainly close to the
425:"Small Intestinal Cancer: a Population-Based Study of Incidence and Survival Patterns in the United States, 1992 to 2006"
1176:
850:
763:
673:
47:
1116:
892:
868:
562:
MedicineNet. Retrieved April 4, 2023, from https://www.medicinenet.com/is_small_intestine_cancer_curable/article.htm
854:
413:
Maguire A, Sheahan K. Primary small bowel adenomas and adenocarcinomas-recent advances. Virchows Arch 2018;473:265–73
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665:
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134:
1181:
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1022:
810:
682:
97:
354:
882:
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606:
1087:
1069:
1009:
838:
834:
303:
92:
293:
1154:
1106:
1097:
820:
722:
691:
491:
464:
446:
130:
72:
64:
269:
Age: Cancer risk increases with age. The average age diagnosis is 65.(Cleveland Clinic, 2022)
955:
829:
744:
732:
454:
436:
153:
77:
56:
797:
780:
351:
326:
309:
209:
114:
81:
250:
1111:
1074:
1004:
902:
842:
785:
714:
704:
459:
424:
298:
258:
188:
126:
125:(the latter two parts of the small intestine). Duodenal cancer has more in common with
1201:
1055:
737:
288:
611:
508:
Chen AC, Neugut AI. Malignant
Neoplasms of the Small Intestine. eMedicine.com. URL:
380:
1017:
101:
441:
358:
622:
1082:
1035:
978:
922:
60:
17:
1168:
423:
Qubaiah, O.; Devesa, S. S.; Platz, C. E.; Huycke, M. M.; Dores, G. M. (2010).
347:
279:
Sex: Males are 25% more likely to develop the disease.(Cleveland Clinic, 2022)
634:
509:
450:
1064:
987:
805:
596:
284:
495:
468:
1127:
203:
180:
of histopathologic types of small intestine cancers, and their prognoses.
149:
85:
579:
145:
118:
591:
546:
Small intestine cancer: Symptoms, causes, Prognosis & Treatment
249:
122:
129:, while cancer of the jejunum and ileum have more in common with
1124:
287:
tumors of the small intestine associated with dietary intake of
638:
117:(the first part of the small intestine) and cancer of the
569:
553:
Intestinal cancer: Causes, symptoms & treatments
1167:
1096:
1054:
977:
968:
943:
921:
819:
796:
771:
762:
713:
690:
681:
672:
573:
91:
71:
37:
32:
265:Risk factors for small intestine cancer include:
429:Cancer Epidemiology, Biomarkers & Prevention
381:"SEER Stat Fact Sheets: Small Intestine Cancer"
113:Small intestine cancer can be subdivided into
63:. Pathology specimen. The prominent folds are
650:
261:of duodenum seen in the post-bulbar duodenum.
41:Small bowel cancer, cancer of the small bowel
8:
184:Subtypes of small intestine cancer include:
974:
768:
687:
678:
657:
643:
635:
570:
510:http://www.emedicine.com/MED/topic2651.htm
46:
29:
913:Hereditary nonpolyposis colorectal cancer
539:Key statistics for small intestine cancer
458:
440:
318:hereditary nonpolyposis colorectal cancer
171:
1138:Intraductal papillary mucinous neoplasm
372:
337:
218:
7:
206:-These cancers start in lymphocytes.
148:of the small intestine arise in the
1187:Desmoplastic small round cell tumor
888:Polymerase proofreading-associated
560:Is small intestine cancer curable?
67:, a characteristic of small bowel.
59:that encroaches into lumen of the
25:
750:Hereditary diffuse gastric cancer
558:Radhakrishnan, R. (2021, May 6).
537:American Cancer Society. (2023).
1046:Nodular regenerative hyperplasia
340:
233:
221:
1148:Solid pseudopapillary neoplasm
951:Gastrointestinal stromal tumor
908:Familial adenomatous polyposis
314:familial adenomatous polyposis
195:Gastrointestinal stromal tumor
1:
956:Krukenberg tumor (metastatic)
551:Markman, M. (2022, July 20).
442:10.1158/1055-9965.EPI-10-0328
1177:Primary peritoneal carcinoma
851:traditional serrated adenoma
512:. Accessed on: June 2, 2006.
308:Hereditary gastrointestinal
1117:Pancreatic ductal carcinoma
1224:
1133:Serous microcystic adenoma
728:Signet ring cell carcinoma
666:Digestive system neoplasia
544:Cleveland Clinic. (2022).
1041:Focal nodular hyperplasia
54:
45:
1143:Mucinous cystic neoplasm
993:Hepatocellular carcinoma
847:sessile serrated adenoma
135:Five-year survival rates
1208:Gastrointestinal cancer
1182:Peritoneal mesothelioma
931:Squamous cell carcinoma
700:Squamous cell carcinoma
1023:Hepatocellular adenoma
811:Pseudomyxoma peritonei
322:Peutz–Jeghers syndrome
262:
181:
33:Small intestine cancer
355:neuroendocrine tumour
253:
175:
168:Histopathologic types
144:Approximately 50% of
1028:Cavernous hemangioma
879:Familial adenomatous
866:Polyposis syndromes:
484:Am. J. Gastroenterol
1088:Gallbladder cancer
1070:Cholangiocarcinoma
1010:Liver angiosarcoma
944:Upper and/or lower
893:Serrated polyposis
304:Radiation exposure
263:
182:
102:blood in the stool
1195:
1194:
1163:
1162:
1155:Pancreatoblastoma
1107:exocrine pancreas
964:
963:
939:
938:
758:
757:
723:Gastric carcinoma
632:
631:
334:Additional images
131:colorectal cancer
107:
106:
65:plicae circulares
27:Medical condition
16:(Redirected from
1215:
975:
874:MUTYH-associated
859:Cronkhite–Canada
830:Colorectal polyp
769:
745:Linitis plastica
733:Gastric lymphoma
688:
679:
659:
652:
645:
636:
571:
531:
528:
522:
519:
513:
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500:
499:
479:
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444:
435:(8): 1908–1918.
420:
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405:
402:
396:
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393:
391:
377:
344:
310:cancer syndromes
237:
225:
210:Carcinoid tumors
154:ampulla of Vater
78:Gastroenterology
57:carcinoid tumour
50:
30:
21:
1223:
1222:
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1198:
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1191:
1159:
1092:
1050:
960:
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917:
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781:Duodenal cancer
773:Small intestine
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352:small intestine
345:
336:
327:Cholecystectomy
294:Crohn's disease
248:
241:
238:
229:
226:
170:
115:duodenal cancer
82:general surgery
28:
23:
22:
18:Ileal neoplasms
15:
12:
11:
5:
1221:
1219:
1211:
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1200:
1199:
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1190:
1189:
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1160:
1158:
1157:
1151:
1150:
1145:
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1135:
1120:
1119:
1114:
1112:Adenocarcinoma
1102:
1100:
1094:
1093:
1091:
1090:
1078:
1077:
1075:Klatskin tumor
1072:
1060:
1058:
1052:
1051:
1049:
1048:
1043:
1031:
1030:
1025:
1013:
1012:
1007:
1005:Hepatoblastoma
1002:
1001:
1000:
983:
981:
972:
966:
965:
962:
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958:
953:
947:
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937:
936:
934:
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927:
925:
919:
918:
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910:
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903:Adenocarcinoma
896:
895:
890:
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876:
871:
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861:
825:
823:
817:
816:
814:
813:
808:
802:
800:
794:
793:
791:
790:
789:
788:
786:Adenocarcinoma
777:
775:
766:
760:
759:
756:
755:
753:
752:
747:
742:
741:
740:
730:
725:
719:
717:
711:
710:
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705:Adenocarcinoma
702:
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574:Classification
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566:External links
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299:Celiac disease
296:
291:
280:
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259:adenocarcinoma
247:
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228:Adenocarcinoma
227:
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214:
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207:
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189:Adenocarcinoma
169:
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127:stomach cancer
105:
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98:vomiting blood
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1056:Biliary tract
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998:Fibrolamellar
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855:Peutz–Jeghers
852:
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833:
831:
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826:
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751:
748:
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739:
738:MALT lymphoma
736:
735:
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731:
729:
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490:(3): 703–10.
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359:H&E stain
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289:saturated fat
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55:Picture of a
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1123:
1105:
1081:
1063:
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1016:
986:
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839:hyperplastic
828:
821:Colon/rectum
772:
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483:
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388:. Retrieved
384:
375:
264:
246:Risk factors
215:
183:
162:
158:
143:
139:
112:
108:
1083:gallbladder
1036:hyperplasia
61:small bowel
38:Other names
1169:Peritoneum
367:References
348:Micrograph
255:Endoscopic
1128:neoplasms
1065:bile duct
988:malignant
970:Accessory
900:Neoplasm:
883:Gardner's
806:Carcinoid
692:Esophagus
451:1055-9965
285:carcinoid
257:image of
240:Carcinoid
178:incidence
176:Relative
137:are 65%.
73:Specialty
1202:Category
1098:Pancreas
869:Juvenile
843:juvenile
798:Appendix
674:GI tract
496:15743371
469:20647399
204:Lymphoma
150:duodenum
146:adenomas
93:Symptoms
86:oncology
835:adenoma
715:Stomach
623:D007414
460:2919612
390:18 June
119:jejunum
1125:cystic
1018:benign
494:
467:
457:
449:
979:Liver
764:Lower
683:Upper
350:of a
276:2022)
123:ileum
923:Anus
618:MeSH
607:9-CM
492:PMID
465:PMID
447:ISSN
392:2014
121:and
612:152
603:ICD
597:C17
588:ICD
488:100
455:PMC
437:doi
385:NCI
1204::
1131::
857:,
853:,
849:,
845:,
841:,
837:,
621::
610::
595::
592:10
486:.
463:.
453:.
445:.
433:19
431:.
427:.
383:.
357:.
320:,
316:,
312::
133:.
100:,
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80:,
1109::
1085::
1067::
1038::
1020::
990::
881:/
832::
658:e
651:t
644:v
605:-
590:-
580:D
498:.
471:.
439::
394:.
361:.
197:-
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
