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Dogs typically undergo antibiotic treatment to eliminate infectious pathogens or parasites and to prevent secondary infections. However, the treatment with antibiotics can also disrupt the ecosystems of beneficial microorganisms in dog's gastrointestinal (GI) tract. When dogs with digestive disorders
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has a wide range of potential benefits which are still being studied. Though it is being used as probiotic supplements in treating constipation, diarrhea, relieving stress, and enhancing immune response among birds and small animals, human trials are still limited.
272:, the dogs diagnosed with parvovirus infection were shown to exhibit severe gastrointestinal distress such as vomiting and bloody diarrhea. After the treatment for three days, the bloody diarrhea ceased and the dogs had solid stools.
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species are sensitive to acidic exposure and have difficulty surviving environments with low pH, such as stomach acid. Therefore, obtaining consistent and reproducible results becomes the major challenge for the commercial products
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Lee SH, Lillehoj HS, Park DW, Hong YH, and Lin JJ. 2007. Effects of
Pediococcus –and Saccharomyces -based probiotic (MitoMax) on coccidiosis in broiler chickens. Comparative Immuno Microbiol & Infectious disease.
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is a facultative anaerobe with lesser sensitivity to oxygen. Pediococci exert antagonism against other microorganisms, including enteric pathogens, primarily through the production of lactic acid and secretion of
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probiotic products, the surviving millions of bacteria are able to alleviate the disrupted balance of microorganisms in dogs’ GI tracts caused by antibiotics treatment and to normalize the intestinal microflora.
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Barros R.R., Carvalho G.S., Peralta J.M., Facklam R.R., Teixeira L.M. 2001. Phenotypic and genotypic characterization of
Pediococcus strains isolated from human clinical sources. J. Clin Microbiol. April;39(4):
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Dalloul R.A., Lillehoj H.S, Lee J.S., Lee S.H., Chung K.S. 2006. Immunopotentiating effect of a
Fomitella fraxinea – derived lectin on chicken immunity and resistance to coccidiosis. Poult. Sci. 85: 446S-451S
301:-specific antibody levels while also reducing the number of oocysts shed by possible competitive inhibition and pediocin production, which inhibit pathogenic bacteria and other Gram-positive spoilage.
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has not been stated in any literature to have toxic effects. Another potential benefit of using them as probiotics is their use as alternative medicines against infectious parasitic pathogens such as
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that has shown promising results in animal and human experiments, though some of the results are limited. They are commonly found in fermented vegetables, fermented dairy products, and meat.
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is a homofermentative bacterium that can grow in a wide range of pH, temperature, and osmotic pressure, therefore being able to colonize the digestive tract. It has emerged as a potential
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of an optimum pH of 6.2, with an overnight incubation at 37 and 45 °C (99 and 113 °F). It is also viable at higher temperatures up to 65 °C (149 °F).
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Lee SH, Lillehoj HS, Dalloul RA, Park DW, Hong YH, and Lin JJ. 2007. Influence of
Pediococcus –based probiotic on coccidiosis in broiler chickens. Poultry Sci. 86:63-66
528:"Probiotics (Direct-Fed Microbials) in Poultry Nutrition and Their Effects on Nutrient Utilization, Growth and Laying Performance, and Gut Health: A Systematic Review"
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Lin J.J. 2006. Probiotics as alternative
Biomedicines for pets with digestive disorders. Proceeding of 8th Annual meeting of JBVP. 3-288-292.
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are sensitive to room temperature, which raises concerns for storage conditions and maintenance of cell viability. In addition, most
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product can have better beneficial effects in dogs and cats' GI tracts when administered with antibiotics.
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Ennahar S., Deschamps N. 2000. Anti-Listeria effect of enoterocin A, produced by cheese-isolated
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EFM01, relative to other bacteriocins from lactic acid bacteria. J.Appl. Microbiol. 88:449S-457S
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has been used to treat dogs with digestive disorders and also those dogs which were infected by
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440:"Structural Basis of Pore Formation in the Mannose Phosphotransferase System by Pediocin PA-1"
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605:] unique probiotics we use as a novel GI supplement. Annual Meeting of JBVP. 3-269-3-272
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Lin J.J. 2006. Probiotics as alternative
Biomedicines for pets with digestive disorders
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Mizutani W., Yamasaki R, Lin, JJ, Kuki M, and Kato G. 2007. Pediococcus-an [
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Daeschel M.A., Klaenhaemmer T.R. 1985. Association of a 13.6-megadalton plasmid in
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is also known to prevent colonization of the small intestine by pathogens such as
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Moreover, since antibiotics kill many of competitive pathogenic microorganisms,
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have shown enhanced immune responses against infectious coccidioidal diseases.
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This species is also acidophilic, viable at very low pH. The probiotic
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with bacteriocin activity. Appl. Environ. Microbiol. 50: 1538S-1541S
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Zhu, Liyan; Zeng, Jianwei; Wang, Chang; Wang, Jiawei (2022-02-08).
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Jha, Rajesh; Das, Razib; Oak, Sophia; Mishra, Pravin (2020).
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Klaenhammer T.R. 1993. Genetics of bacteriocins produced by
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can function as an immune modulator. Animals fed with
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stimulates humoral immune response to produce higher
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177:cocci that is often found in pairs or tetrads.
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630:- the Bacterial Diversity Metadatabase
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344:Difference from other probiotic strains
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393:. FEMS Microbiol. Rev. 12 :39S-85S
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193:de Man, Rogosa, Sharpe agar
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823:Bacteria described in 1887
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53:Scientific classification
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769:pediococcus-acidilactici
649:Pediococcus acidilactici
624:Pediococcus acidilactici
189:Pediococcus acidilactici
170:Pediococcus acidilactici
155:Pediococcus acidilactici
41:Pediococcus acidilactici
25:Pediococcus acidilactici
426:Pediococcus pentosaceus
269:Saccharomyces boulardii
305:Immune health benefits
289:in broiler chickens.
247:among small animals.
238:Clostridium difficile
505:Enterococcus faecium
456:10.1128/AEM.01992-21
391:lactic acid bacteria
323:Antibiotic treatment
293:in conjunction with
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207:known as pediocins.
138:P. acidilactici
16:Species of bacterium
545:10.3390/ani10101863
251:Digestive disorders
211:Potential benefits
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725:iNaturalist
338:Pediococcus
125:Pediococcus
812:Categories
577:30:261-268
403:1241–1246.
377:References
260:parvovirus
232:Salmonella
464:1098-5336
183:probiotic
133:Species:
76:Bacillota
743:11070775
664:Q7159284
658:Wikidata
564:33066185
482:34851716
226:Shigella
107:Family:
71:Phylum:
64:Bacteria
59:Domain:
45:MRS agar
717:3227360
673:BacDive
555:7602066
532:Animals
473:8824269
299:Eimeria
286:Eimeria
235:spp.,
119:Genus:
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88:Bacilli
83:Class:
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756:964697
730:559566
704:975457
626:at Bac
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241:, and
229:spp.,
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738:IRMNG
691:769TB
782:1254
777:NCBI
764:LPSN
751:ITIS
712:GBIF
678:6381
628:Dive
560:PMID
478:PMID
460:ISSN
369:and
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699:EoL
686:CoL
603:sic
550:PMC
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