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as a
Professor of Molecular Sciences in 2002. She was named Paul V Galvin Professor in 2012. In 2014, Fromme was appointed Director of the Centre for Applied Structural Discovery. The following year she was selected as a Regents' Professor. At Arizona State, she oversaw the development of two compact
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In an effort to design new drugs, Fromme has studied the structure of disease-linked enzymes in the human body including
Taspase I. The protease is involved with cell metabolism, proliferation, migration and termination, and its dysregulation is implicated in the genesis of various cancers. By
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to analyze proteins. These lasers, which produce extremely bright and ultra-short pulses of light, allow for serial femtosecond nanocrystallography. Whilst conventional high intensity X-ray pulses can damage the molecules they are interrogating, femtosecond pulses can permit the acquisition of
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She also has published and co published many scientific papers in many journals, like; Three-Dimensional structure of
Cyanobacterial photosystem I at 2.5 Ă… resolution, Crystal Structure of photosystem II from Synechococcus elongatus at 3.8 Ă… resolution, Femtosecond X-ray protein
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investigating
Taspase I with free-electron lasers, Fromme showed that there is a critical helical region which defines the protease activity, and eliminating this region can deactiviate the enzyome entirely. X-ray Free Electron Lasers also allowed for the characterisations of
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diffraction patterns before the sample degrades. Femtosecond measurements allowed Fromme to establish the structure-property relationships of crucial biological systems, including
171:. Nanocrystallography will allow for the development of more safe and effective drugs, as well as accelerating our understanding of material design for renewable energy sources.
106:. Her research considers the structure-to-function relationship of the membrane proteins involved with infectious diseases and bio-energy conversion. In 2021, she was awarded the
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Zouni A; Witt HT; Jan Kern; Fromme P; Norbert KrauĂź; Saenger W; Orth P (1 February 2001). "Crystal structure of photosystem II from
Synechococcus elongatus at 3.8 A resolution".
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P Jordan; P Fromme; H T Witt; O Klukas; W Saenger; Norbert KrauĂź (1 June 2001). "Three-dimensional structure of cyanobacterial photosystem I at 2.5 A resolution".
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is a German-American chemist who is
Director of the Biodesign Center for Applied Structural Discovery and Regents Professor at the
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Die ATP-Synthase aus
Chloroplasten biochemische Untersuchungen zur Struktur und kinetische Messungen zum Mechanismus des Enzyms
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Die ATP-Synthase aus
Chloroplasten biochemische Untersuchungen zur Struktur und kinetische Messungen zum Mechanismus des Enzyms
683:"Bright lights, big science: Revolutionary laser instrument receives $ 4.7 million boost from the National Science Foundation"
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nano-crystallography, Single mimivirus particulars intercepted and imaged with an X-Ray Laser, and so much more.
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X-ray accelerator systems, including an X-ray light source and an X-ray Free
Electron Laser.
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707:"Time-resolved Femtosecond Crystallography: Toward Molecular Movies of Molecules In Action"
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556:"ASU appoints Petra Fromme as director of new Center for Applied Structural Discovery"
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604:"Beuses' $ 10 million gift to build world's first-of-its-kind X-ray laser lab at ASU"
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402:. SĂ©bastien Boutet, Petra Fromme, Mark S. Hunter. Cham, Switzerland. 2018.
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for undergraduate studies, where she majored in biochemistry. She moved to
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827:"Research team finds possible new approach for sleeping sickness drugs"
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532:"ASU protein pioneer honored as innovator at governor's celebration"
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X-ray free electron lasers : a revolution in structural biology
950:"First detailed look at crucial enzyme advances cancer research"
779:"Photosynthesis seen in a new light by rapid X-ray pulses"
659:"The sounds of science: A quiet home for a powerful laser"
635:"Petra Fromme honored with the prestigious Anfinsen Award"
580:"Three ASU faculty members appointed Regents' Professors"
803:"X-ray study unlocks secrets of light-sensing organism"
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Fromme was amongst the first people to use high energy
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for her doctoral research, where she investigated the
1022:"ASU research makes Science's top 10 breakthroughs"
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508:"New ASU center to expand cutting-edge research"
146:Institute, part of the TU Berlin. Fromme joined
1077:Academic staff of Technische Universität Berlin
875:"X-ray pulses reveal structure of viral cocoon"
331:"Femtosecond X-ray protein nanocrystallography"
329:; Anton Barty; et al. (3 February 2011).
974:"X-ray eyes peer deeper into deadly pathogen"
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430:: CS1 maint: location missing publisher (
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923:"Finding answers to cancer in the cosmos"
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142:Fromme's academic career started at the
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1047:"Fromme garners Best of Phoenix award"
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181:, the bacterium which gives rise to
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204:Top 10 Breakthrough of the Year
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128:Technische Universität Berlin
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216:2021 Fromme was awarded the
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156:X-ray free-electron lasers
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978:Biodesign Institute | ASU
954:Biodesign Institute | ASU
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903:Biodesign Institute | ASU
879:Biodesign Institute | ASU
855:Biodesign Institute | ASU
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807:Biodesign Institute | ASU
783:Biodesign Institute | ASU
735:Biodesign Institute | ASU
711:Biodesign Institute | ASU
687:Biodesign Institute | ASU
663:Biodesign Institute | ASU
608:Biodesign Institute | ASU
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560:Biodesign Institute | ASU
536:Biodesign Institute | ASU
124:Free University of Berlin
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1097:21st-century biochemists
755:"BioXFEL - Petra Fromme"
462:Arizona State University
148:Arizona State University
114:Early life and education
104:Arizona State University
66:Arizona State University
1117:American women chemists
16:German-American chemist
487:(Thesis) (in German).
481:Fromme, Petra (1988).
178:Francisella tularensis
1107:German women chemists
434:) CS1 maint: others (
225:Selected publications
213:Best of Phoenix Award
512:The Arizona Republic
70:Max Volmer Institute
349:10.1038/NATURE09750
138:Research and career
122:. She attended the
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134:of chloroplasts.
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325:Henry N Chapman;
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639:EurekAlert!
1071:Categories
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1007:2023-04-11
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899:"Research"
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444:References
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144:Max Volmer
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426:cite book
383:Q27644346
357:1476-4687
318:Q27629975
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183:Tularemia
1026:ASU News
379:Wikidata
375:21293373
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