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Polysaccharide krestin (PSK) was first isolated in Japan in the late 1960s while PSP was isolated about 1983 in China. Each compound has shown remarkable anticancer properties with few side effects. By 1987 PSK accounted for more than 25% of total national expenditure for anticancer agents in Japan.
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Ng TB (1998). "A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom
Coriolus versicolor (Basidiomycetes: Polyporaceae)".
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