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Polysaccharide-K

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Mitomi T, Tsuchiya S, Iijima N, et al. (February 1992). "Randomized, controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. The Cooperative Study Group of Surgical Adjuvant Immunochemotherapy for Cancer of Colon and Rectum (Kanagawa)".
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Hayakawa K, Mitsuhashi N, Saito Y, et al. (1997). "Effect of Krestin as adjuvant treatment following radical radiotherapy in non-small cell lung cancer patients".
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Iino Y, Yokoe T, Maemura M, et al. (1995). "Immunochemotherapies versus chemotherapy as adjuvant treatment after curative resection of operable breast cancer".
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PSK is one of the most commonly used medicinal mushroom extracts with a long history as an additive in cancer therapy in Asia, especially in Japan. PSK has
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Suto T, Fukuda S, Moriya N, et al. (1994). "Clinical study of biological response modifiers as maintenance therapy for hepatocellular carcinoma".
480:"A randomized trial of chemoimmunotherapy of acute nonlymphocytic leukemia in adults using a protein-bound polysaccharide preparation" 165: 566:
Fisher M, Yang LX (2002). "Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy".
286:"Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curative resections of gastric cancer" 537:"Antimetastatic effects of PSK (Krestin), a protein-bound polysaccharide obtained from basidiomycetes: an overview" 645: 93:, and the protein component is reported at the β-1,6 side chain. PSK is isolated from the "CM-101" strain of 135: 98: 536: 190:"Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy" 70:
in various types of cancers, including colorectal, gastric, breast, liver, pancreatic, and lung cancer.
155: 89:β-1,4 main chain with β-1,3 and β-1,6 side chains. The approximate molecular weight of PSK is 100,000 160:. Chapter Eight - An overview of fungal glycan-based therapeutics: Academic Press. pp. 135–163. 241:"Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy" 130: 48: 517: 460: 367: 323: 77:
for colorectal cancer, non-small cell lung carcinoma, breast cancer, liver cancer, and leukemia.
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Oba K, Teramukai S, Kobayashi M, Matsui T, Kodera Y, Sakamoto J (June 2007).
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Preliminary studies examining PSK include its use in conjunction with
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Progress in Molecular Biology and Translational Science
605:Memorial Sloan-Kettering Cancer Center's page for 154:Yang, Dandan; Zhou, Zijing; Zhang, Lijuan (2019). 478:Ohno R, Yamada K, Masaoka T, et al. (1984). 541:Cancer Epidemiology, Biomarkers & Prevention 85:PSK is a protein polysaccharide consisting of a 8: 535:Kobayashi H, Matsunaga K, Oguchi Y (1995). 23:, the mushroom from which PSK was isolated. 503: 309: 215: 205: 101:, is derived from the "COV-1" strain of 146: 7: 441:Cancer Chemotherapy and Pharmacology 595:American Cancer Society's page for 14: 623:by the MD Anderson Cancer Center. 484:Cancer Immunology, Immunotherapy 344:Diseases of the Colon and Rectum 290:Cancer Immunology, Immunotherapy 115: 617:"Detailed Scientific Review of 387:Cancer Detection and Prevention 46:isolated from the mycelium of 1: 188:Habtemariam, Solomon (2020). 632:information from Drugs.com. 207:10.3390/biomedicines8050135 662: 302:10.1007/s00262-006-0248-1 97:. The analogous compound 136:Polysaccharide peptide 24: 621:and Polysaccharide-K" 251:(3). Anticancer Res. 239:M, Fisher; LX, Yang. 19: 630:and Polysaccharide-K 610:and Polysaccharide-K 600:and Polysaccharide-K 443:. 33 Suppl: S145–8. 64:anti-tumor activity 628:Trametes versicolor 619:Trametes versicolor 608:Trametes versicolor 598:Trametes versicolor 568:Anticancer Research 414:Anticancer Research 245:Anticancer Research 131:Medicinal mushrooms 103:Trametes versicolor 95:Trametes versicolor 49:Trametes versicolor 21:Trametes versicolor 496:10.1007/BF00205503 449:10.1007/BF00686688 356:10.1007/BF02050666 25: 653: 584: 583: 563: 557: 556: 532: 526: 525: 507: 475: 469: 468: 436: 430: 429: 409: 403: 402: 382: 376: 375: 338: 332: 331: 313: 281: 275: 274: 272: 271: 236: 230: 229: 219: 209: 185: 179: 178: 176: 174: 151: 125: 120: 119: 118: 28:Polysaccharide-K 661: 660: 656: 655: 654: 652: 651: 650: 646:Medicinal fungi 636: 635: 592: 587: 565: 564: 560: 534: 533: 529: 477: 476: 472: 438: 437: 433: 420:(6B): 2907–11. 411: 410: 406: 384: 383: 379: 340: 339: 335: 283: 282: 278: 269: 267: 238: 237: 233: 187: 186: 182: 172: 170: 168: 153: 152: 148: 144: 121: 116: 114: 111: 83: 58: 12: 11: 5: 659: 657: 649: 648: 638: 637: 634: 633: 624: 613: 603: 591: 590:External links 588: 586: 585: 574:(3): 1737–54. 558: 527: 470: 431: 404: 377: 333: 276: 231: 180: 166: 145: 143: 140: 139: 138: 133: 127: 126: 110: 107: 82: 79: 57: 54: 44:polysaccharide 13: 10: 9: 6: 4: 3: 2: 658: 647: 644: 643: 641: 631: 629: 625: 622: 620: 614: 611: 609: 604: 601: 599: 594: 593: 589: 581: 577: 573: 569: 562: 559: 554: 550: 547:(3): 275–81. 546: 542: 538: 531: 528: 523: 519: 515: 511: 506: 501: 497: 493: 490:(3): 149–54. 489: 485: 481: 474: 471: 466: 462: 458: 454: 450: 446: 442: 435: 432: 427: 423: 419: 415: 408: 405: 400: 396: 392: 388: 381: 378: 373: 369: 365: 361: 357: 353: 350:(2): 123–30. 349: 345: 337: 334: 329: 325: 321: 317: 312: 307: 303: 299: 296:(6): 905–11. 295: 291: 287: 280: 277: 266: 262: 258: 254: 250: 246: 242: 235: 232: 227: 223: 218: 213: 208: 203: 199: 195: 191: 184: 181: 169: 167:9780128177402 163: 159: 158: 150: 147: 141: 137: 134: 132: 129: 128: 124: 113: 108: 106: 104: 100: 96: 92: 88: 80: 78: 76: 71: 69: 68: 63: 55: 53: 51: 50: 45: 41: 37: 33: 29: 22: 18: 627: 618: 607: 597: 571: 567: 561: 544: 540: 530: 487: 483: 473: 440: 434: 417: 413: 407: 390: 386: 380: 347: 343: 336: 293: 289: 279: 268:. Retrieved 248: 244: 234: 197: 194:Biomedicines 193: 183: 171:. Retrieved 156: 149: 123:Fungi portal 102: 94: 84: 75:chemotherapy 72: 65: 59: 47: 35: 31: 27: 26: 20: 393:(1): 71–7. 87:beta-glucan 270:2023-12-22 200:(5): 135. 173:24 January 142:References 257:0250-7005 81:Chemistry 640:Category 580:12168863 522:24000083 505:11039289 465:25538345 372:68080825 320:17106715 311:11030720 265:12168863 226:32466253 109:See also 67:in vitro 62:adjuvant 56:Research 553:7606203 514:6391658 457:8137477 426:8669887 399:9043766 364:1735313 217:7277906 42:-bound 40:protein 38:) is a 32:Krestin 578:  551:  520:  512:  502:  463:  455:  424:  397:  370:  362:  328:161680 326:  318:  308:  263:  255:  224:  214:  164:  518:S2CID 461:S2CID 368:S2CID 324:S2CID 576:PMID 549:PMID 510:PMID 453:PMID 422:PMID 395:PMID 360:PMID 316:PMID 261:PMID 253:ISSN 222:PMID 175:2023 162:ISBN 52:. 500:PMC 492:doi 445:doi 352:doi 306:PMC 298:doi 212:PMC 202:doi 99:PSP 36:PSK 642:: 615:A 572:22 570:. 543:. 539:. 516:. 508:. 498:. 488:18 486:. 482:. 459:. 451:. 418:15 416:. 391:21 389:. 366:. 358:. 348:35 346:. 322:. 314:. 304:. 294:56 292:. 288:. 259:. 249:22 247:. 243:. 220:. 210:. 196:. 192:. 105:. 91:Da 34:, 612:. 602:. 582:. 555:. 545:4 524:. 494:: 467:. 447:: 428:. 401:. 374:. 354:: 330:. 300:: 273:. 228:. 204:: 198:8 177:. 30:(

Index


protein
polysaccharide
Trametes versicolor
adjuvant
in vitro
chemotherapy
beta-glucan
Da
PSP
Fungi portal
Medicinal mushrooms
Polysaccharide peptide
Progress in Molecular Biology and Translational Science
ISBN
9780128177402
"Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy"
doi
10.3390/biomedicines8050135
PMC
7277906
PMID
32466253
"Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy"
ISSN
0250-7005
PMID
12168863
"Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curative resections of gastric cancer"
doi

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