67:. Regions of heterochromatin can spread and influence transcription, which may result in the cessation of gene expression and subsequently, white eye sectors.
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that regulate neighboring genes. These local enhancers can also affect the expression pattern of the transgene. Since each
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has the transgene in a different location each transgenic organism has the potential for a unique expression pattern.
63:. These phenotypes are often due to a chromosomal translocation such that the color gene is now close to a region of
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is well characterised by unstable expression of a gene that results in the red eye coloration. In the
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145:"Figure 4-45. Position effects on gene expression in two different eucaryotic organisms"
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Weiler K, Wakimoto B (1995). "Heterochromatin and gene expression in
Drosophila".
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Effect on the expression of a gene when its location in a chromosome is changed
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is also used to describe the variation of expression exhibited by identical
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flies the eyes typically have a mottled appearance of white and red
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81:. In this case the difference in expression is often due to
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153:(4th ed.). New York: Garland Science.
44:with respect to eye color and is known as
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119:10.1146/annurev.ge.29.120195.003045
38:. This has been well described in
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150:Molecular biology of the cell
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