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Ron Heeren

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31: 201:. In 2014, he was appointed to his current position as one of the scientific directors of M4I at Maastricht University. He was president of the Dutch Society of Mass Spectrometry between 2001–2005. He is one of the founding members of the Mass Spectrometry Imaging Society, and was elected its president in 2017. 161:
During his postdoctoral fellowship, he worked on the development of innovative ion sources, vacuums systems, data acquisition systems and novel temperature-controlled ion cyclotron resonance cells. He used the FTICR-MS instrument for the study of collisional energy transfer and internal energy
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Heeren’s academic research interests are fundamental studies of the energetics of macromolecular systems, conformational studies of non-covalently bound protein complexes, translational imaging research, high-throughput bioinformatics, and the development and validation of new mass
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As a project leader (1995–1997), Heeren led the application of high-resolution MS (FTICR-MS, FTIR imaging spectroscopy and SIMS) to the field of conservation science. He discovered and identified saponified pigment particulates in so-called protrusions in Rembrandt’s
423:Ščupáková, Klára; Soons, Zita; Ertaylan, Gökhan; Pierzchalski, Keely A.; Eijkel, Gert B.; Ellis, Shane R.; Greve, Jan W.; Driessen, Ann; Verheij, Joanne; De Kok, Theo M.; Olde Damink, Steven W. M. (17 April 2018). 72:
Hans Fisher Fellowship; Thomson Medal of IMSF; NWO-Physics Valorisation Prize; Brightlands Convention Award; Robert Feulgen lecturer, Society for Histochemistry; Distinguished Wiley Visiting Scientist award;
961:<739::aid-jms3>3.0.co;2-# "Structural analysis of synthetic homo- and copolyesters by electrospray ionization on a Fourier transform ion cyclotron resonance mass spectrometer" 315:
Ellis, Shane R.; Paine, Martin R. L.; Eijkel, Gert B.; Pauling, Josch K.; Husen, Peter; Jervelund, Mark W.; Hermansson, Martin; Ejsing, Christer S.; Heeren, Ron M. A. (2018-05-21).
525:"Use of advantageous, volatile matrices enabled by next-generation high-speed matrix-assisted laser desorption/ionization time-of-flight imaging employing a scanning laser beam" 181:
detector has been adapted to enable microscope-mode imaging mass spectrometry for biomolecules to enable combined high-throughput and high-resolution molecular imaging using
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research group on macromolecular ion physics and biomolecular imaging mass spectrometry (1995–2014). He was also professor at the chemistry faculty of
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distributions. These methods were deployed to investigate their role in the determination of dissociation pathways of biomolecular systems.
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Between 1995 and 2015, he worked on new approaches towards high spatial resolution and high-throughput molecular imaging mass spectrometry using
906:"Manipulating internal energy of protonated biomolecules in electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry" 1590: 1118: 226:
2020     Hans Fisher Senior Fellowship, Institute of Advanced Studies, Technical University of Munich Hans Fisher senior fellowship
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and the scientific director of the Multimodal Molecular Imaging Institute (M4I), where he heads the division of Imaging Mass Spectrometry.
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Guo, Xinghua; Duursma, Marc C.; Kistemaker, Piet G.; Nibbering, Nico M. M.; Vekey, Karoly; Drahos, Laszlo; Heeren, Ron M. A. (June 2003).
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Heeren and his group have pioneered the development of active pixelated detectors for mass spectrometry imaging. One such detector, the
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2010     Distinguished Wiley Visiting Scientist award, Environmental Molecular Sciences Laboratory, Department of Energy, US
1853: 1583: 366:"Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry" 1338: 476:"Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids" 229:
2020     Thomson medal, International Mass Spectrometry Foundation for distinguished contribution to international MS
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Bruinen, Anne L.; Fisher, Gregory L.; Balez, Rachelle; van der Sar, Astrid M.; Ooi, Lezanne; Heeren, Ron M. A. (2018-06-12).
1858: 1742: 1016:"Localization of intramolecular monosulfide bridges in lantibiotics determined with electron capture induced dissociation" 198: 1833: 1555: 959:
Koster, Sander; Duursma, Marc C.; Boon, Jaap J.; Nielen, Michel W. F.; de Koster, Chris G.; Heeren, Ron M. A. (2000).
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Jungmann, Julia H.; Smith, Donald F.; MacAleese, Luke; Klinkert, Ivo; Visser, Jan; Heeren, Ron M. A. (2012-07-27).
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Kleinnijenhuis, Anne J.; Duursma, Marc C.; Breukink, Eefjan; Heeren, Ron M. A.; Heck, Albert J. R. (2003-07-01).
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Heeren has coauthored over 300 peer-reviewed articles, which have been cited over 12,600 times (Google Scholar).
105: 1451: 1081:"Integrating imaging FTIR and secondary ion mass spectrometry for the analysis of embedded paint cross-sections" 1766: 1746: 121: 1848: 1500: 523:
Ogrinc PotoÄŤnik, Nina; Porta, Tiffany; Becker, Michael; Heeren, Ron M. A.; Ellis, Shane R. (2015-10-28).
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Jungmann, Julia H.; MacAleese, Luke; Visser, Jan; Vrakking, Marc J. J.; Heeren, Ron M. A. (2011-10-15).
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Jungmann, Julia H.; MacAleese, Luke; Visser, Jan; Vrakking, Marc J. J.; Heeren, Ron M. A. (2011-10-15).
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Ellis, Shane R.; Jungmann, Julia H.; Smith, Donald F.; Soltwisch, Jens; Heeren, Ron M. A. (2013-10-18).
109: 1541: 1732: 264:Ščupáková, Klára; Dewez, Frédéric; Walch, Axel K.; Heeren, Ron M. A.; Balluff, Benjamin (2020-08-17). 1828: 1802: 1676: 1648: 1152: 972: 917: 862: 636: 536: 377: 1672: 1710: 244:
2012     Award, Exploratory Measurement Science Group (EMSG), University of Edinburgh, UK
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Drahos, null; Heeren, null; Collette, null; De Pauw E, null; Vekey, null (December 1999).
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Ellis, S. R.; Soltwisch, J.; Paine, M. R. L.; Dreisewerd, K.; Heeren, R. M. A. (2017).
457: 424: 406: 365: 317:"Automated, parallel mass spectrometry imaging and structural identification of lipids" 298: 265: 1822: 1792: 1772: 1756: 1718: 1658: 1640: 197:
From 2008 to 2013, Heeren was the research director for emerging technologies at the
1339:"NWO Physics Valorisation Prize goes to Ron Heeren from Maastricht University | NWO" 1180: 1065: 672: 356: 1806: 1141:"Fourier Transform Infrared Microscopic Imaging of an Embedded Paint Cross-Section" 960: 515: 425:"Spatial Systems Lipidomics Reveals Nonalcoholic Fatty Liver Disease Heterogeneity" 253:
2002     Bert L. Schram Award, Dutch Society for Mass Spectrometry (NVMS)
266:"Morphometric Cell Classification for Single-Cell MALDI-Mass Spectrometry Imaging" 241:
2013     Winner, 10th Venture Challenge, Netherlands Genomics Initiative
615:"Biological Tissue Imaging with a Position and Time Sensitive Pixelated Detector" 440: 171: 614: 316: 1796: 1517: 1314: 1140: 1085:
ICOM-CC Triennial Meeting (12th), Lyon, 29 August-3 September 1999: Preprints.
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10.1002/(sici)1097-0231(19980915)12:17<1175::aid-rcm305>3.0.co;2-l
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2008     RCM Beynon Prize, Rapid Communications in Mass Spectrometry
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Van Der Weerd, J.; Brammer, H.; Boon, J. J.; Heeren, R. M. A. (March 2002).
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10.1002/(SICI)1096-9888(199912)34:12<1373::AID-JMS907>3.0.CO;2-#
850: 574:"Enhanced detection of high-mass proteins by using an active pixel detector" 573: 1227: 1196:"High Dynamic Range Bio-Molecular Ion Microscopy with the Timepix Detector" 1110: 1057: 1000: 945: 890: 764: 713: 682:"High Dynamic Range Bio-Molecular Ion Microscopy with the Timepix Detector" 664: 605: 589: 564: 507: 466: 415: 348: 307: 281: 1266: 1099:"Recitative after Rembrandt's "The Anatomy Lesson of Dr. Nicolaes Tulp"" 475: 1195: 1079:
Heeren, Ron M. A.; Boon, Jaap J.; Noble, Petria; Wadum, Jørgen (1999).
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spectrometry–based proteomic imaging techniques for the life sciences.
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2014     Robert Feulgen lecturer, Society for Histochemistry
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Heeren holds 7 patents and has established two spin-off companies,
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10.1002/1096-9888(200006)35:6<739::aid-jms3>3.0.co;2-#
631: 128: 851:"Thermal energy distribution observed in electrospray ionization" 217:. In 2019, he was awarded the NWO Valorisation Prize in Physics. 214: 1579: 1501:"Press release: Omics2Image wins Venture Challenge Spring 2013" 1105:, University of Pittsburgh Press, pp. 78–79, 2005-03-23, 232:
2019     NWO-Physics Valorisation prize (see above)
1315:"NWO Physics Valorisation Prize 2019 - Ron Heeren - YouTube" 723:"Mass Spectrometric Imaging for Biomedical Tissue Analysis" 210: 1387:
Maastricht, Minderbroedersberg 4-6 6211 LK (25 May 2020).
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Heeren obtained a PhD degree in Technical Physics at the
1363:"Heeren, Ron M.A. - Institute for Advanced Study (IAS)" 619:
Journal of the American Society for Mass Spectrometry
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Journal of the American Society for Mass Spectrometry
83: 68: 60: 52: 40: 21: 721:Chughtai, Kamila; Heeren, Ron M. A. (2010-05-12). 578:Angewandte Chemie International Edition in English 1291:"Mass Spectrometry Imaging Society – MS Imaging" 1518:"iDirector interview with Ron Heeren - YouTube" 810:Heeren, Ron M. A.; VĂ©key, Károly (1998-09-15). 235:2019     Brightlands Convention Award 144:matrix-assisted laser desorption and ionization 108:. He is currently a distinguished professor at 1452:"Uitreiking Brightlands Convention Award 2018" 1591: 1242:"Maastricht University Magazine October 2014" 124:in 1992 under the supervision of Aart Kleyn. 8: 1556:"Rapid Communications in Mass Spectrometry" 1427:"International Mass Spectronomy Foundation" 1411:: CS1 maint: numeric names: authors list ( 1598: 1584: 1576: 1389:"Thomson Medal 2020 awarded to Ron Heeren" 29: 18: 1039: 816:Rapid Communications in Mass Spectrometry 754: 630: 529:Rapid Communications in Mass Spectrometry 456: 405: 297: 1844:Academic staff of Maastricht University 778: 270:Angewandte Chemie International Edition 168:The Anatomy Lesson of Dr. Nicolaes Tulp 1404: 7: 1542:"New EMSL Visiting Scientists Named" 16:Dutch mass spectrometry researcher 14: 140:secondary ion mass spectrometry 1864:University of Amsterdam alumni 1: 199:Netherlands Proteomics Centre 1477:"Society for Histochemistry" 965:Journal of Mass Spectrometry 910:Journal of Mass Spectrometry 855:Journal of Mass Spectrometry 441:10.1021/acs.analchem.7b05215 170:” in collaboration with the 1839:21st-century Dutch chemists 1393:www.maastrichtuniversity.nl 1880: 104:) is a Dutch scientist in 1729:Catherine Clarke Fenselau 1614: 649:10.1007/s13361-012-0444-5 390:10.1007/s13361-018-1979-x 333:10.1038/s41592-018-0010-6 106:mass spectrometry imaging 91: 87:Imaging Mass Spectrometry 76: 28: 1854:Thomson Medal recipients 1165:10.1366/0003702021954683 1767:Marcos Nogueira Eberlin 1450:Redactie (2019-03-27). 480:Chemical Communications 258:Most cited publications 193:Professional activities 122:University of Amsterdam 64:University of Amsterdam 1111:10.2307/j.ctvthhc5r.38 590:10.1002/anie.201305501 282:10.1002/anie.202007315 1725:Catherine E. Costello 1481:www.histochemistry.eu 215:Dutch Screening Group 174:museum in The Hague. 110:Maastricht University 1859:Mass spectrometrists 1803:Jennifer S. Brodbelt 1649:Nico M. M. Nibbering 1560:Wiley Online Library 1200:Analytical Chemistry 1145:Applied Spectroscopy 1020:Analytical Chemistry 686:Analytical Chemistry 429:Analytical Chemistry 47:Tilburg, Netherlands 1834:People from Tilburg 1697:Richard M. Caprioli 1608:Thomson Medal Award 1157:2002ApSpe..56Q.275V 977:2000JMSp...35..739K 922:2003JMSp...38..597G 867:1999JMSp...34.1373D 641:2012JASMS..23.1679J 584:(43): 11261–11264. 541:2015RCMS...29.2195O 382:2018JASMS..29.1571B 276:(40): 17447–17450. 1606:Recipients of the 1456:Conference Matters 492:10.1039/c7cc02325a 133:Utrecht University 35:Ron Heeren in 2017 1816: 1815: 1777:Albert J. R. Heck 1763:Scott A. McLuckey 1753:Carol V. Robinson 1747:František TureÄŤek 1743:Alexander Makarov 1683:John Bennett Fenn 1669:Michael T. Bowers 1635:Alfred O. C. Nier 1627:Keith R. Jennings 1248:. 14 October 2014 1212:10.1021/ac2017629 1206:(20): 7888–7894. 1120:978-0-8229-8033-9 1032:10.1021/ac0263770 1026:(13): 3219–3225. 861:(12): 1373–1379. 822:(17): 1175–1181. 791:scholar.google.nl 787:"Ron M.A. Heeren" 739:10.1021/cr100012c 698:10.1021/ac2017629 692:(20): 7888–7894. 625:(10): 1679–1688. 535:(23): 2195–2203. 486:(53): 7246–7249. 205:Commercialization 116:Scientific career 95: 94: 78:Scientific career 1871: 1733:Peter Roepstorff 1715:Michael L. Gross 1701:Franz Hillenkamp 1691:Alan G. 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Index


Tilburg
mass spectrometry imaging
Maastricht University
University of Amsterdam
FOM-AMOLF
Utrecht University
secondary ion mass spectrometry
matrix-assisted laser desorption and ionization
The Anatomy Lesson of Dr. Nicolaes Tulp
Mauritshuis
Medipix
MALDI
SIMS
Netherlands Proteomics Centre
Omics2Image/ASI
Dutch Screening Group
"Morphometric Cell Classification for Single-Cell MALDI-Mass Spectrometry Imaging"
doi
10.1002/anie.202007315
ISSN
1433-7851
PMC
7540554
PMID
32668069
"Automated, parallel mass spectrometry imaging and structural identification of lipids"
doi
10.1038/s41592-018-0010-6
ISSN

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