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lot of referencing one-off or dated studies with no follow-up and very little in the way of technical information in the exposure levels (especially the current recommended levels and it's relation to toxicity or how current usage guidelines are related to current studies. For now, someone with a more technical explanation can come along and clean it up, but if that does not succeed in a moderate time frame, I may attempt to tackle it myself. As it stands, there's a lot of "could", "might" and "may" and given the recent inquiries into it's efficacy, I'm certain more recent studies have been done that may affirm (thus adding a secondary source) or conflict with the data currently used in the article.
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1178:"Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment" Eaton, David L.; Daroff, Robert B.; Autrup, Herman; Bridges, James; Buffler, Patricia; Costa, Lucio G.; Coyle, Joseph; McKhann, Guy; Mobley, William C.; Nadel, Lynn; et al. Critical Reviews in Toxicology (2008), 38(Suppl. 2), 1-125. Abstract: "A review. This review examines the large body of toxicol. and epidemiol. information on human exposures to chlorpyrifos, with an emphasis on the controversial potential for chlorpyrifos to induce neurodevelopmental effects at low doses..."--
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reference to an inference taken from the a J. Forensic Leg. Med. article, ref. 6 as of this date, and repeated primary source-arguments in the biological/medical main sections). For instance, in the toxicity mechanisms section, whole paragaphs and subsections stand on single primary source, including, in one case, a source that carries the expression "Preliminary
Observations" in its title. This article clearly should be tagged for violation of WP sourcing standards, whatever editors might feel about the regulatory status of the agent in their jurisdictions. Le Prof
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information listed on
Knowledge (XXG) and would be a valuable addition to the page. This includes experimental code numbers, formulations, action group, outside U.S. registration information, safety guidelines, handling/storage information, emergency guidelines, and a comprehensive list of suppliers, brand names, premix partners, and discontinued products.
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1172:"A summary of recent findings on birth outcomes and developmental effects of prenatal ETS, PAH, and pesticide exposures” Perera, F. P.; Rauh, V.; Whyatt, R. M.; Tang, D.; Tsai, W. Y.; Bernert, J. T.; Tu, Y. H.; Andrews, H.; Barr, D. B.; Camann, D. E.; et al. Neurotoxicology (2005), 26(4), 573-587. DOI: 10.1016/j.neuro.2004.07.007
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The section under "Human
Exposure" uses a secondary source when the primary source is readily available. "However as of 2016, EPA scientists had not been able to find any level of exposure to the pesticide that was safe." However, this sentence is misleading since it implies that they found that any
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This article is currently unbalanced in its content. For such a widely used insecticide that is approved by regulatory agencies worldwide, there must be a positive benefit-to-risk ratio. Currently, this article really says little about its benefits (small sections on use and application) while the
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The "Adulthood" subheading under the "Toxicity and Safety" section seems to say two different things in the second line about increased lung cancer risk. The first sentence says that an increase in lung cancer risk was observed in pesticide applicators, but the second sentence says a lower risk rate
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Came here today to find background information on a topic widely appearing in news about 2017 EPA decisions. Disappointed: The article misuses primary sources, drawing firm conclusions in the lede and in the main body based solely on primary sources, in some cases, as few as one (see e.g., see lede
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I have made a few minor changes reflecting a more unbiased tone, mostly in the lede to notate the accurate sourcing in the body of the article, which uses a lot of singular studies and as such, has quantifiers with it (may, could, possibly). I agree this article is still unbalanced, as there is a
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The synthesis states that "O,O-diethyl phosphorochloridothioate" is used, but an ethyl group has two carbons and the substance shown clearly only has one carbon per group so if anything, the substance is "O,O-dimethyl phosphorochloridothioate" As I cannot vouch for the correctness of the described
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Further the partial quote "...this assessment indicates that dietary risks from food alone are of concern..." is not a conclusion of the assessment but is part of an explanation of the methodology. Likewise the quote "chlorpyrifos may not provide a sufficiently health protective human health risk
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I am interested in adding an
External Link for this product that directs users to its product information page on the Crop Protection Database (CPD). The CPD is a fact-based, neutral listing of technical information for crop protection products. The CPD listing for this product expands upon the
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Criteria for selecting literature is potentially problematic. Chlorpyrifos has been the subject of 16,197 reports (as of 5 August, 2014). So selection of individual research papers risks being capricious or random (this is what came up when I Googled). For topics where the literature is so
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I agree. It also has a non-relavant political undertone such as inserting a comment such as: "The Dow
Chemical Company, a major producer of chlorpyrifos for use on food for human consumption, contributed $ 1 million to the Donald J. Trump inaugural committee on December 26, 2016".
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I am moving these out of the "external links" section as they're not truly external links, and because there are so many articles about this pesticide I think general papers (rather than reviews, overviews etc) should only be listed if they are cited in the article.
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The sections on exposure blend human and rat data in a way that is confusing. One suggestion is to separate the animal data and human results. The
Knowledge (XXG) standards for such reports differ, but we need to be clear that there are two sets of experiments.
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I've begun addressing these comments in several of the sections on the page (e.g., related to effects from exposure early in life and related to potential mechanisms other than acetylcholinesterase inhibition), but I have not completely incorporated them yet.
1128:]. I can't tell if the redirect is mistakenly pointing here because someone thought that it was just another synonym for this compound, or if this is a and attempt to have a single entry for two very similar (and related) pesticides. --
1175:"Age dependence of organophosphate and carbamate neurotoxicity in the postnatal rat: extrapolation to the human” Vidair, Charles A. Toxicology and Applied Pharmacology (2004), 196(2), 287-302. DOI: 10.1016/j.taap.2003.12.016
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I notice the comment below with heading "Either bad or unclear redirect" says that there are both ethyl & methyl forms. It sounds like there is further work needed to structure the article (or articles) accordingly.
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I can confirm that I recently bought a package of 0.5% Chlorpyrifos in the form of Hot Shot MaxAttrax Roach Bait at a local
Walmart here in Oklahoma City, OK. The issue of the ban rumor is addressed directly here:
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As creator of the file, I have to make clear that all the shown structures as well as the reaction path is correct. The reaction equation is based on the industrial synthesis method for this compound stated in
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assessment given the potential for neurodevelopmental outcomes." is not a conclusion of the assessment as implied, but is stating the concern that lead to the undertaking of the assessment in the first place.
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Of the 105 reviews published since 2004, these three are both highly cited, in
English, and focus on human-health. They might be relied on to supplant some of the primary references in the article:
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1156:. Since 2004, about 100 reviews have appeared, some of these highly cited and many of these focusing on health issues. Relying on those would possibly enhance the objectivity of the article. --
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Unlike probabilities, death rolls never seem to sum to unity, un unfortunate undercurrent that makes these blunt declarations resemble nothing so much as tabloid click-bait. —
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Salyha Y. Biological effects assessment of chlorpyrifos and some aspects of its neurotoxicity // Visnyk of Lviv
University. - Biology series. - Is. 54, Lviv. - 2010. - P.3-14.
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majority of the article is about toxicity, health effects, environmental concerns, etc. A more neutral, balanced approach to discussing this topic is needed. --
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Someday The Onion is going to run the headline: "Five Deaths from Old Age Now
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was observed. Which is it? The second source indicates that a higher rate for pesticide applicators was observed; the first source is now a dead link.
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This is still available for sale as an agricultural insecticide. Source: I sell agricultural chemicals for a large ag-chemical retailer. <ref: -->
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It is currently used in cockroach baits "HotShot Max-Attrax Roach Bait" - see any product description for details. Clearly not completely banned.
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Chlorpyrifos-methyl redirects to here - however this is a different compound from Chlorpyrifos (sometimes referred to as Chlorpyrifos-ethyl) See
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It is an effective broad spectrum pesticide with health concerns. We mention uses first and foremost. Does not look to bad to me currently.
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That clipped second sentence simply can't stand on its own in this context, and it really ought to be more specific regardless.
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It acts on the nervous system of insects by inhibiting acetylcholinesterase. Toxicity results in more than 10,000 deaths a year.
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I'm not seeing a problem. The synthesis for chlorpyrifos is correct. Chlorpyrifos methyl is a different but related chemical.
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Is the sale of Chlorpyrifos banned in the US? It is no longer available in California. It was sold under the name Dursban.
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exposure was unsafe and that is not the case. Due to poor and conflicting data they were unable to reach a conclusion.
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regulation section seems a bit lengthy and is almost solely focused on the united states. is this a concern to anyone?
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Please add in the infobox with hilight about whether it is carcinogenic or not, and how much carcinogenic it is?
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to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the
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to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the
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http://thehill.com/policy/energy-environment/401086-court-orders-trump-epa-to-ban-controversial-pesticide
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https://www.federalregister.gov/documents/2024/02/05/2024-02153/chlorpyrifos-reinstatement-of-tolerances
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If you have discovered URLs which were erroneously considered dead by the bot, you can report them with
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If you have discovered URLs which were erroneously considered dead by the bot, you can report them with
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on Knowledge (XXG). If you would like to participate, please visit the project page, where you can join
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on Knowledge (XXG). If you would like to participate, please visit the project page, where you can join
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The article also does not make it clear that the acceptable daily dose includes a 100X safety factor.
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articles on environment-related topics, as well as to ensure that environment articles are properly
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https://web.archive.org/20060421162206/http://www.panna.org:80/campaigns/docsDrift/SecondhandPs.pdf
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before doing mass systematic removals. This message is updated dynamically through the template
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before doing mass systematic removals. This message is updated dynamically through the template
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https://www.chemservice.com/oo-dimethyl-phosphorochloridothioate-n-12704-250mg-26065.html
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If you found an error with any archives or the URLs themselves, you can fix them with
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If you found an error with any archives or the URLs themselves, you can fix them with
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1509:"Chlorpyrifos Leads to Oxidative Stress-Induced Death of Hippocampal Cells in Vitro."
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tolerances in the US likely to be reinstated as a rollback on the 2021 regulations.
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That link doesn't work at the moment. I guess give it some time and see if it does.
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in recent months. Which "benefits" does it have in comparison to other pesticides?
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The substance contains two ethyl (not methyl) groups. Hence, everything is fine. —
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https://web.archive.org/20090824081746/http://www.cdms.net:80/ldat/ld0AT004.pdf
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1434:. No special action is required regarding these talk page notices, other than
1282:. No special action is required regarding these talk page notices, other than
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Please strongly consider approving my request. For more information, visit:
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after the link to keep me from modifying it. Alternatively, you can add
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after the link to keep me from modifying it. Alternatively, you can add
373:, a collaborative effort to improve the coverage of articles related to
905:. Furthermore, a quick SciFinder search resulted in the same equation.
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I would have guessed billions and billions, or no-one would buy it.
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http://www.farmoz.com.au/label/farmoz/STRIKE_OUT_500WP_16103844.pdf
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to keep me off the page altogether. I made the following changes:
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to keep me off the page altogether. I made the following changes:
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Is chlorpyriphos carcinogenic? Please add and hilight in infobox.
720:. Please visit the project page for details or ask questions at
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http://www.farmchemicalsinternational.com/cropprotection/cpd/
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When you have finished reviewing my changes, please set the
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When you have finished reviewing my changes, please set the
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http://www.chlorpyrifos.com/myths-vs-facts.htm#BannedInTheUS
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Unknown-importance Occupational Safety and Health articles
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Knowledge (XXG):WikiProject Occupational Safety and Health
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Misuse of secondary sources and misleading partial quote.
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http://www.panna.org/campaigns/docsDrift/SecondhandPs.pdf
291:. To participate, help improve this article or visit the
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I have just added archive links to one external link on
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I have just added archive links to 2 external links on
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synthesis, I have, however, not changed the article
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WikiProject Occupational Safety and Health articles
1438:using the archive tool instructions below. Editors
1286:using the archive tool instructions below. Editors
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Template:WikiProject Occupational Safety and Health
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838:http://www.cdms.net/LDat/ld73D000.pdf</ref: -->
407:This article has not yet received a rating on the
1867:soon, another update for the regulation section.
1511:Neurophysiology, Vol. 45, No. 3, 2013.P.193-199.
33:for general discussion of the article's subject.
1911:C-Class Occupational Safety and Health articles
1574:The possible safety risks of chlorpyrifos have
903:Pesticide Synthesis Handbook by Thomas A. Unger
716:and that biomedical information in any article
1424:This message was posted before February 2018.
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714:Manual of Style for medicine-related articles
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1368:. Please take a moment to review
1226:. Please take a moment to review
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1495:more sources
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19:This is the
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612:Environment
597:categorized
585:environment
537:Environment
485:Agriculture
476:agriculture
432:Agriculture
31:not a forum
1895:Categories
1543:Unbalanced
1107:Sbergman27
1099:Sbergman27
961:References
929:Yilloslime
808:cyclosarin
669:Toxicology
1707:Doc James
1629:Doc James
1470:this tool
1463:this tool
1318:this tool
1311:this tool
1199:E.Thorsos
1180:Smokefoot
1158:Smokefoot
1000:Regards,
298:Chemicals
288:chemicals
251:Chemicals
88:if needed
71:Be polite
21:talk page
1834:unsigned
1757:unsigned
1717:contribs
1639:contribs
1599:Edgar181
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1525:unsigned
1476:Cheers.—
1376:cbignore
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1324:Cheers.—
1234:cbignore
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1060:WP:MEDRS
1048:contribs
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1023:. (See:
888:Gould363
841:Patahorn
819:unsigned
799:Untitled
729:Medicine
664:Medicine
178:Springer
143:Cochrane
56:get help
29:This is
27:article.
1651:Concur
1486::Online
1415:checked
1370:my edit
1334::Online
1263:checked
1228:my edit
858:Saittam
756:on the
639:on the
589:neutral
512:on the
325:on the
222:C-class
1693:MaxEnt
1653:DocTox
1606:Jarble
1580:Jarble
1384:nobots
1242:nobots
1002:Judygt
228:scale.
166:OpenMD
136:PubMed
1721:email
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1613:Seola
1069:cont.
601:Read
573:This
192:Wiley
84:Seek
1883:talk
1858:Leyo
1856:. --
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591:and
504:High
317:High
185:Trip
159:Gale
151:DOAJ
73:and
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1444:RfC
1406:to
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1064:2/0
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748:Low
631:Mid
403:???
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