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inhibitors (INSTIs), a fusion inhibitor, a CCR5 antagonist, a CD4 T lymphocyte (CD4) post-attachment inhibitor, and a gp120 attachment inhibitor. There are also two drugs, ritonavir (RTV) and cobicistat (COBI) which can be used as pharmacokinetic (PK) enhancers (or boosters) to improve the PK profiles of PIs and the INSTI elvitegravir (EVG)."
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Hi,TB and Hiv and Aids did not yet kiss me goodbye all in one but diffreciate at treatment levels and why others pro-long lives and why mpox sex related matters and why vaccine is needed and why Hiv and Aids vaccination is no where to found and how much it will cost ours all to pay for it??.Amooketsi
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I don't know if that's also the case with HIV or if by now it can be considered endemic - circulating at some baseline level through affected countries and no longer seen as an emergency through health systems. The WHO and UN-related websites still mention that it is "epidemic" (even in contexts like
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Is it a "Global Pandemic", a "Pandemic" or is it not "Pandemic" at all? Is it just something "Some authors" think or is it a widespread scientific consensus about this determination? Shouldn't this be determined by actual up to date information rather than what the situation looked like 15 years age?
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The opening summary states that "HIV/AIDS is considered a pandemic—a disease outbreak which is present over a large area and is actively spreading." with a citation from 2008. It should be noted that 15 years is a very long time with regards to the notion of a "pandemic", nor does this text identify
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Recommended revision is "Depending on the guidelines being followed, initial treatment generally consists of two nucleoside reverse transcriptase inhibitors along with a third ARV, either an integrase strand transfer inhibitor (INSTI), a non-nucleoside reverse transcriptase inhibitor (NNRTI), or a
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Please add the following sentence: "There are eight classes of antiretroviral agents (ARVs), and over 30 individual drugs: nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase, inhibitors (NNRTIs), protease inhibitors (PIs), integrase strand transfer
2634:(2) Requested edits for "As of 2010, more than 6.6 million people were receiving HAART in low- and middle-income countries." to " As of 2022, 39 million people globally were living with HIV, and 29.8 million people were accessing ART." The citation for this statement is the 2023 UNAIDS Fact Sheet: 2554:
Later in the "Epidemiology" section it curtly states that "Some authors consider HIV/AIDS a global pandemic." First of all, "Some authors" are not a credible and authoritative source of information of whether something is or isn't a pandemic, global or otherwise. "Some authors" could be anyone.
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I think male circumcision should be removed from the list. I think the list creates an image that circumcision is as effective in prevention as the other listed methods, which is not the case. Epidemiologyclly speaking it might be a risk reducting method but the other listed methods reduce
2591:'Ending the HIV/AIDS epidemic by 2030'), so I don't feel the case for it being a pandemic is as hard to make as you imply, even if references could use an update. If references to pandemic status are removed there should be citations supporting that view. 2290:
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AIDS (Acquired Immunodeficiency Syndrome) is a spectrum of conditions caused by HIV (Human Immunodeficiency Virus). HIV is a retrovirus that can be managed with treatment. Left untreated HIV can lead to AIDS.
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Infection with HIV (Human Immunodeficiency Virus), a retrovirus, can be managed with treatment but without treatment can lead to a spectrum of conditions including AIDS (Acquired Immunodeficiency Syndrome).
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are described as spanning several decades. In all those cases the definition can be attributed to the fact that the disease kept spreading to new areas of the globe, at the pace of contemporary means of
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It is not yet over for this poverty,hunger and emission free world and is a challenge to all as climate,earthquake, conflicts damages infrastructure and taking lives by storm.
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and edit the lead directly, but a lot of stuff there seems important. If forced to drop it to 3 paragraphs, which the MOS says is typical for
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Extensive copy and pastes of large sections of Knowledge without appropriate attribution or release under the appropriate license.
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to some readers, to ensure a quality article and complete coverage of its subject matter. For more information, please refer to
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https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf
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https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf
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https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf
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individual’s risk to ~0%. No one should believe they are safe with circumcition and neglect safe sex and then get infected.
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This sentence has a typo ('AIDs'), is generally poorly constructed/unclear, and likely out of place (better suited for
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Prevention: Safe sex, needle exchange, male circumcision, pre-exposure prophylaxis, post-exposure prophylaxis
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HIV (and how to treat it) in the AIDS article. Maybe something like this and without the excessive commas --
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who exactly has decided that it is a "pandemic". Are they an acknowledged public authority on the subject?
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Again it should be stressed that 15 years is a very, very long time with regards to "Pandemics".
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10 paragraphs, which even for a topic this important seems excessive to me. I wish I could
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protease inhibitor with a pharmacokinetic enhancer (also known as a booster)."
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https://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf
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says that "it began ... in 541 and continued 750 or 767". The dates for the
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Understanding and Management of Special Child in Pediatric Dentistry
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It's not necessarily a "very, very long time". The page for the
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https://www.cdc.gov/hiv/basics/livingwithhiv/treatment.html
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Second, this citation is yet another 15 year old article.
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2889: 2884: 2879: 2869: 2868: 2854:41.114.165.131 2842: 2839: 2812:MOS:LEADLENGTH 2807: 2804: 2803: 2802: 2748: 2747: 2728: 2717: 2714: 2685: 2682: 2608: 2605: 2604: 2603: 2588: 2547: 2544: 2513: 2510: 2495:Rent (musical) 2482: 2477: 2474: 2473: 2461: 2458: 2457: 2452: 2448: 2446: 2443: 2442: 2425: 2385: 2339: 2338: 2333: 2327: 2320: 2319: 2316: 2315: 2311: 2310: 2304: 2303: 2288: 2276: 2275: 2274: 2273: 2259: 2246: 2227: 2203: 2191: 2190: 2187: 2186: 2183: 2182: 2179: 2178: 2175: 2174: 2147: 2146: 2145: 2144: 2138: 2118: 2110: 2102: 2094: 2080: 2072: 2061: 2045:Here are some 2044: 2018: 2017: 2012: 2007: 2002: 1996: 1993: 1992: 1984: 1983: 1976:Top-importance 1972: 1966: 1965: 1963: 1946:the discussion 1933: 1932: 1916: 1904: 1903: 1901:Top‑importance 1895: 1883: 1882: 1879: 1878: 1869: 1859: 1858: 1851:Top-importance 1847: 1841: 1840: 1838: 1821:the discussion 1808: 1807: 1791: 1779: 1778: 1776:Top‑importance 1764: 1752: 1751: 1748: 1747: 1745: 1711: 1699: 1698: 1693: 1681: 1680: 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1270: 1266: 1263:(assessed as 1262: 1261: 1251: 1247: 1246: 1242: 1239:(assessed as 1238: 1237: 1227: 1223: 1222: 1218: 1214: 1208: 1205: 1204: 1201: 1184: 1180: 1176: 1175: 1167: 1166:Africa portal 1156: 1154: 1151: 1147: 1146: 1142: 1135: 1131: 1127: 1122: 1119: 1116: 1112: 1100: 1096:LGBT articles 1083: 1079: 1075: 1071: 1070: 1069: 1060: 1049: 1047: 1044: 1040: 1039: 1035: 1032: 1029: 1026: 1022: 1009: 1000: 996: 995: 991: 987: 983: 982: 972: 968: 967: 963: 960:(assessed as 959: 958: 948: 944: 943: 939: 936:(assessed as 935: 934: 924: 920: 919: 915: 911: 905: 902: 901: 898: 881: 880: 875: 871: 867: 866: 858: 847: 845: 842: 838: 837: 833: 812: 808: 803: 800: 797: 793: 780: 776: 770: 767: 766: 763: 759:AIDS articles 746: 742: 738: 734: 733: 728: 725: 721: 720: 716: 710: 707: 704: 700: 695: 691: 685: 677: 676: 666: 657: 656: 645: 640: 636: 632: 628: 624: 620: 618: 612: 607: 602: 598: 596: 595: 591: 588: 584: 583: 579: 577: 576: 572: 569: 565: 564: 560: 558: 557: 553: 550: 549:April 8, 2006 546: 545: 541: 539: 538: 534: 531: 527: 526: 522: 519: 516: 515: 509: 503: 499: 495: 491: 488: 484: 483: 478: 476: 475: 467: 463: 459: 458: 457: 451: 448: 445: 441: 440: 436: 432: 428: 425: 422: 418: 417: 409: 405: 401: 395: 394: 390: 387: 383: 382: 363: 362: 357: 353: 345: 341: 337: 333: 329: 325: 321: 317: 313: 309: 305: 301: 297: 293: 289: 285: 281: 277: 273: 269: 265: 261: 257: 253: 249: 245: 242: 240: 236: 235: 230: 226: 223: 220: 216: 212: 209: 206: 203: 202:ScienceDirect 200: 197: 194: 190: 186: 182: 178: 174: 170: 167: 164: 160: 154: 150: 149: 141: 140:Verifiability 138: 136: 133: 131: 128: 127: 126: 117: 113: 111: 108: 106: 102: 99: 97: 94: 93: 87: 83: 82:Learn to edit 79: 76: 71: 70: 67: 66: 62: 56: 52: 48: 47: 40: 37: 35: 34: 25: 19: 2848:— Preceding 2844: 2809: 2779: 2757: 2754: 2751: 2743: 2732:edit request 2699: 2694: 2692: 2688: 2687: 2671:Blossiraptor 2663: 2659: 2656: 2648: 2644: 2641: 2633: 2612: 2610: 2557: 2553: 2549: 2526: 2521: 2515: 2490: 2484: 2479: 2463: 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1728:discussion 1696:Disability 1082:discussion 621:column on 460:under the 2816:currently 2788:Seawolf35 2780:Not done: 2561:Arcade222 2252:provides 2233:provides 2114:Citations 678:is rated 611:Main Page 118:if needed 101:Be polite 51:talk page 24:Talk:AIDS 2850:unsigned 2518:§ Stigma 2487:§ Stigma 2335:Archives 2224:HIV/AIDS 2122:Copyedit 2054:Requests 2047:Botswana 1951:Botswana 1942:Botswana 1898:Botswana 1714:HIV/AIDS 1126:Eswatini 990:Medicine 981:selected 885:Medicine 802:Medicine 680:GA-class 561:Promoted 542:Reviewed 474:reassess 450:HIV/AIDS 427:HIV/AIDS 239:Archives 208:Springer 173:Cochrane 86:get help 59:This is 57:article. 55:HIV/AIDS 18:Talk:HIV 2820:be bold 2464:90 days 2166:history 2162:discuss 2134:Cleanup 2005:history 1978:on the 1853:on the 1671:on the 1582:on the 1555:Viruses 1546:viruses 1502:Viruses 1477:on the 1388:on the 1215:on the 1134:Namibia 1130:Lesotho 984:on the 912:on the 777:on the 613:in the 580:Demoted 520:Process 352:90 days 2695:before 2231:PubMed 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