Talk:Ozone therapy

2484:

was applied and there was an improvement in condition does not mean the improvement was directly related to the treatment. By excluding from the statements additional information (from pre-existing conditions of the patients to the additional forms of treatment applied at the same time as the ozone therapy), the paraphrasings you list exclusively work to imply the ozone therapy caused the improvements. Baring the release of empirical evidence to support such, they are, by definition, claims. Further, ‘anecdotal’ exactly communicates that a limited number of claims without empirical evidence have been made. It’s an accurate use of the word. If and when any party produces confirmed physical evidence to show a causal link between the treatment and the outcome, I will more than happily yield to different phrasing. In the interim, you should clearly indicate that the clinicians are reporting whatever improvements they claim without using statements of fact. Again, anyone can report anything... and we should be mindful to list claims as such baring evidence to support said claims. A casual reading of your contributions would make the average viewer believe the patients actually had improvements; instead, clinicians reported improvements but failed to provide actual evidence in support of their reports. Are we to take the words of persons just because they called up a newspaper?

854:

herniation, claiming to show results and patients are indeed satisfied; it is not subsidised by the state, but it is a legal practice. Before WLU's edits, the article showed the view that this is a legal and established practice in some states, now it says "Some marketers of ozone generators make fantastic promotional claims " (very encyclopedical...). I edited the article in the least biased way I could to represent facts as they are, and now you reverted again to WLU's view of the world. I have no idea what MEDRS is, and I won't edit the article again.

2452:, for instance, looks ostensibly like a well-designed trial, but failed to obtain ethics approval. Perhaps the failure to deliver gold-standard research comes down to these researchers' "lack of rigour", as you have insinuated, or perhaps it comes down to institutional reluctance to consider alternate therapies. Who knows? I don't wish to present these reports as anything more than they are, but I also don't want to negatively misrepresent them or leap to conclusions about the competency of the people making them. 158: 2467:

outside of the ozone therapy community has enacted such treatments based on these recommendations". What does it mean to be "outside the ozone therapy community"? Not practicing ozone therapy? Then no hospital outside the community can or will ever practice the therapy, by definition. Or do you mean something else? In which case, what is your evidence regarding the 20+ hospitals offering this treatment in Italy, plus others in China, Portugal, Brazil, Romania and Turkey? This sounds very much like

538: 142: 453: 644: 2395:

this subject simply for fear of encouraging the uninformed to try unproven treatments – and WP is not censored. Nor do I want to uncritically promote this therapy by citing only poor, one-sided research. I feel the information in the article is notable (it has certainly made the Italian and Spanish news!), and I'd like to present it clearly, without hiding the limitations of the evidence, but also without descending into pejoratives,

2733: 559: 403: 385: 243: 1110:

of ozone and hosts training seminars. In the early 1980s, a German survey and investigation into ozone therapy by the University Klinikum in Giessen and the Institute for Medical Statistics, published in the Empirical Medical Acts revealed over 5 million ozone treatments had been delivered to some 350,000 patients, by more than 1000 therapists, of this number about half were

1017:

Eventually it will be common place in the US. Because ozone is a natural substance, pharmco will not endorse it as they cannot patent it. I don't have ozone facts immediately handy, but I am giving you the fact of my experience. I guess I am agreeing that the article is biased, as the practice of using ozone it used in many other countries successfully.

295: 274: 2425:

positive outcomes related to some specific treatment, but without peer-reviewed empirical evidence to back up their claims, they shouldn't be treated factual. You're conveniently and purposefully leaving out important details (like the existence of simultaneous treat unrelated to ozone therapy which may have a more of an impact than the ozone treatment.

2354:: 2018. Participants were 32 patients already taking Lamivudine 150mg and Zidovudine 300mg daily, with high viral load, low CD4 and CD8 counts and adverse reactions to retrovirals. Viral load became undetectable after 1 month in all 32 patients; CD4 and CD8 cells substantially increased; all side effects of antiretroviral drugs disappeared or improved. 305: 1515:

credentials. Nor does the site appear to be a reliable source: it has a polemical tone and its information is very vague and supported by deadlinks. I have searched for the original supporting news articles without luck. It would be useful to have anecdotes of deaths from ozone therapy, if anyone can help locate some more reliable information.

704:) and does not state that he discovered ozone but that he had a patent for "for Ozonized Oxygen Gas and its compounds for inhalation in the treatment of disease as a hygienic agent, and compressing the same in water for internal or medicinal use". This is not the same as having discovered the gas, so I have removed this part of the sentence.-- 3219:“Nrf2 is able to modulate inflammation through multiple mechanisms, such as the regulation of redox homeostasis and the suppression of pro-inflammatory genes. -- Inflammation increases local and systemic ROS level while ROS enhance inflammation. --The Nrf2-KEAP1 mediated ROS-homeostatic control can break this vicious cycle.” (Galié et al.) 1118:, nor is it part of the curriculum at most esteemed medical schools. Proposals to include ozone therapy in German health insurance schemes invoked hostile objections from pharmaceutical researchers who question its evidence base. Former Soviet Union Countries seem also to have had less difficulty in accepting ozone as a medicine. 2448:, but is still evidence. I note that the groups producing these reports are all attempting to begin randomized controlled studies and publish peer-reviewed papers, but to run controlled studies requires ethics approval, which has been difficult to obtain for some of them (though they have had approval to deliver treatment). 1758:"The application of ozone therapy in all public hospitals is still being delayed by prejudice, no fundings, commercial competition by big Pharma and above all by the incomprehensible disinterest, if not plain obstruction, by Health Authorities such as the FDA in USA and the European Medical Association." 3564:

Could you please be more specific? Did you read any of the references? You seem only to react directly without reading. I studied a year at the university of Verona in Italy to grasp it. And I have no intentions to send lies into the world. I will go and check which of the refs I have wedged in, meet

2575:

Starting ~2020-05-04, Clinica Nuestra Señora del Rosario, Ibiza. Randomized controlled open-label. ~208 participants, all with COVID-19 pneumonia. Treatment group receive standard hospital treatment plus autohaemotherapy every 12 hours during 5 days (100-200ml of patient’s blood interacted with 200ml

2483:

It is very difficult for me to assume good faith when you post the statements of the clinicians as fact. Again, someone claiming something does not demonstrate fact. Further, you (and the clinicians for that matter) are attempting to demonstrate causation through proximity. Just because ozone therapy

2406:

Oh, and it bugs me when people say there's "no evidence" of something, when what they mean is insufficient or inconclusive evidence. The American Cancer Society was misrepresented as saying there was "no credible scientific basis" for anti-cancer claims, when what they really said was that there were

2243:

An unreferenced statement mentioning "some evidence for its effectiveness in specific medical applications" was removed from the article's lead paragraph. It seems to me there is actually quite a bit of evidence, so I'm gathering what I can find here, in preparation to add something to that effect to

2223:

The only reference that is actually a clinical review published in a scientific journal is reference 2. It’s cited at the end of the introduction and invalidates every claim made in the introduction regarding ozone being dangerous, pseudoscientific, etc. I can’t even find a scientific journal article

1303:

British Medical Journal sourced content and replaced it with offtopic statements about ozone in the stratosphere and MEDRS violating claims. The edit summary was "Requires more than one paper to change things", which is not a policy or guideline. The edit appears to be vandalism and is being reverted

3061:

The activation of Nrf2 causes the expression of the so-called Antioxidant Response Elements (ARE) genes. ARE genes are normally associated with Kelch Like Ech Associated Proten-1 (KEAP-1). Now when mildly activated, they dissociate from KEAP-1 and transcription of Antioxidant Response Elements (ARE)

2780:

Ozone, on the other hand, when inhaled, immediately reacts with biomolecules present in the ELF and is not transferred into the alveolar capillaries. As a result, ozone has a more powerful oxidative action, harms available substances that should protect the alveoli and causes lung oedema. It doesn't

2466:

Hi again CymHastings. I prefer the language of the edits you've made this time (still not convinced about the words "claim" and "anecdotal", but won't bother arguing). I agree it's sensible to point out the lack of external validation. I'm dubious about this statement: "as of late April, no hospital

2443:

Many research articles are published with authors disclosing conflicts of interest: that doesn't prevent these articles being considered "evidence". Lack of peer review certainly decreases the reliability of evidence very substantially. These reports mostly constitute expert opinion without critical

2410:

I have (please note) also substantially improved the safety section, giving a lot more information on negative side-effects of the treatment (I had to translate a lot of German for this info, it took me ages). I may soon be able to add even more regarding negative effects. So I'm not editing with an

1916:

I suggest: BMJ Case Rep. 2013 Jan 31;2013. pii: bcr2012008249. doi: 10.1136/bcr-2012-008249. The use of ozone therapy in Buruli ulcer had an excellent outcome. Bertolotti A1, Izzo A, Grigolato PG, Iabichella ML. The British Medical Journal's (BMJ)impact factor (2014) is 16.3; it uses a comprehensive

3310:

Cuadrado, Antonio; Rojo, Ana I.; Wells, Geoffrey; Hayes, John D.; Cousin, Sharon P.; Rumsey, William L.; Attucks, Otis C.; Franklin, Stephen; Levonen, Anna-Liisa; Kensler, Thomas W.; Dinkova-Kostova, Albena T. (2019-04). "Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases".

2591:

CymHastings, I was not stating those reports as facts. If you reread my edits you should see liberal use of quotation-marks and words such as "stated", "reported". If you find it hard to assume good faith, please try harder. As I said, I won't bother arguing about the other language, though I still

2582:

Starting ~2020-04-23, Baqiyatallah University of Medical Sciences, Iran. Randomized, controlled, non-blinded. Target of 80 participants. Treatment group receive ozone major autohaemotherapy (100-200cc blood interacted with equal volume of 35μg/mL ozone; volume depending on severity) 1-2 times daily

2491:

I’m sorry if I come across as overly agressive. I’ve seen far too many uneducated people fall prey to claims by miracle workers, and given the popularity (and misuse) of Knowledge as a source for truth for the masses, I fear for people who may interpret your contributions as a factual recounting of

2028:

Case reports are primary sources and so generally not allowed for health claims. The secondary component of primary sources (this promises a review) is sometimes allowed, but is often biased to colour the finding from the primary research. I cannot access the full text of this article so don't know

1109:

Ozone therapy is a well established alternative and complementary therapy in most mainland European countries where health authorities have tolerated its practice. The European Cooperation of Medical Ozone Societies, founded in 1972, publishes guidelines on medical indications and contraindications

3212:

In the research of Galie et al, they provide scientific, histologic and biochemical evidence that treatment with a low concentration of ozone in cultured cells promotes nuclear translocation of Nrf2 at the chromatin sites of active transcription and increases the expression of antioxidant response

2554:

Started 2020-03-26, Rome. Randomized controlled, single-blind on outcomes assessor. ~152 participants. Treatment group receives systemic autohemotherapy with Ozone 30 mcg / ml 250ml 2 times / day for 7 days, plus standard of care. Control group receives standard of care. (Standard of care includes

2487:

Several of the clinics you’ve listed or are cited are alternative medicine establishments and are not part of the mainstream public health community. While other centers may be using ozone therapy (as you listed off), none are necessarily doing so BECAUSE of the recommendations of Dr. Baeza at the

2394:

I'm aware that my edits may raise some questions. I personally have no idea whether ozone therapy is effective for COVID-19 or anything else, and am not affiliated with any ozone proponents; I am simply trying to map out significant evidence around this issue. I don't want to suppress reporting on

944:

Agreed, the bias in the language choice, article selection, expert selection (Ernst is an expert in nothing but asking others to prove negatives), if you would like a line by line content argument, I will gladly oblige. There are as many Pub Med articles that are pro Ozone as there are the select

2944:

Secondly these products will act as second messengers activating enzymes like Superoxide Dismutase (SOD) causing an increase in intra erythrocytic 2,3 DPG level, enhancement of general metabolism through improved oxygen delivery and upregulation of a number of antioxidant enzymes as well of haeme

1348:

Hello. I am sorry if I have been a headache, I was just trying to help. I know many medical websites that ta`lk about ozone therapy, but they're all in Spanish, that's the reason that when I found the declaration I thought it could help improving the article. The next time I am going to edit this

2776:

Oxygen during inhalation penetrates the capillaries of the alveoli and is not being stopped by the antioxidants at the epithelial surface. At the air-epithelium interface, the alveolar cells are constantly overlaid by a very thin (about 0.1 µm) film composed of water, salts and molecules such as

2005:

Is this perhaps good? Spine is a top Journal and this is a Review of Literature Fort NM, Aichmair A, Miller AO, Girardi FP. L5-S1 Achromobacter Xylosoxidans Infection Secondary to Oxygen-Ozone Therapy for the Treatment of Lumbosacral Disc Herniation: A Case Report and Review of the Literature.

725:"Despite a lack of direct support of O3 therapy, the current Food and Drug Administration regulations do not restrict the use of it in situations where it has proven its safety and effectiveness. Nonetheless, there has been support for its safety and effectiveness in multi-international studies." 1786:

Both of those quotes come from the second link, which was published in a well-known predatory open access journal with a history of faked peer-reviews, rushed publication of bad articles and other trust-eroding issues. The first link does not support the claims. Finally, as a rule of thumb, any

1514:

The cited webpage does not say what the sentence says: it lists a different number of cases, in none of which ozone therapy is established as the cause of death, and in most of which the underlying cancer or another therapy is clearly cause of death; it does not mention investigations or false

853:

Hi, by no means I'm going to learn Knowledge "bureaucracy" just to make a vandalism accusation on page that is of no interest to me. Click on the history link I gave; if that is not enough evidence of vandalism, then it's not vandalism. I know a reputable clinic doing ozone injections for disk

2424:

People with a vested interested in making positive claims around a treatment's success is not 'evidence.' Anyone can call up a newspaper and claim "XYZ," and that in and of itself does not constitute evidence. You're welcome to note these assorted ozone therapy clinics are making claims about

3304:

This is a finding that is falling in place with the publication of Cuadrado in Nature Reviews, where ozone is not yet mentioned. Cuadrado states: “a functional NRF2–KEAP1 axis is essential for protection against a plethora of diseases that have oxidative stress and inflammation as underlying

1016:

I've attended Ozone conferences in Europe, where they are very accepted. More and more they are being accepted in the US, primarily right now by sports doctors, who can't necessarily get reimbursed by insurance, but nevertheless use ozone therapy to get results that people will pay for.

3067:

These genes after being induced will produce antioxidant enzymes as Super Oxide Dismutase (SOD), Glutathione Peroxidase (GPx), Glutathione S-transferase (GST) Catalase (CAT) Heme Oxygenase-1 (HO-1) NADPH HSP-70 that will enhance antioxidant processes. .(Noel L.Smith et al) (citation see

2439:

Please assume good faith. I am not "purposely" leaving out information. Very happy for that to be clarified; it helps the article. I thought it was implied by stating that a number of patients were no longer intubated by end of treatment, and didn't really consider stating it more

1646:, this would not be correct in this instance, and I would request that you review the reference and editorial response if you have concerns. Regardless, as you appear to feel strongly about the issue, I will defer, as I do not think your decision negatively impacts the article. 2769:

Also Aspirine is a poison, and a medicine. It depends on the dosage and way of administration. Ozone in microdosages 0-60 max 80 micrograms per ml O2) is a medicine, if used correctly by medical doctors, according to guidelines based on the principles of Evidence Based Medicine

2568:

Starting April 2020, Valencia, Spain. Randomized controlled double-blind. ~50 participants. Treatment group receive WHO-recommended treatment plus autohaemotherapy: 200 mL at 40 mcg/mL of medical ozone / oxygen in 200 mL of patient’s blood. Controls receive WHO-recommended

2492:

the events rather than just the reporting of events by parties with vested interests. We can’t assume everyone is thorough enough to click on the source links; we have to ensure the entries themselves clearly differentiate between reports of facts and actual facts.

2866:

Ozone can be administered either by intramuscular, intra- articular or intra-discal injections, by mixing it with autologous blood and transfusing it back, locally applying it to the skin with bagging and through vaginal or rectal insufflation. Not through

1330:

document, and as stated in the edit comment, I don't think a consensus statement by ozone therapy societies is important to a discussion about ozone therapy itself. The document contains some practice guidelines, but those guidelines are also unreferenced.

813:

and notice all the sections about: countries where the therapy is practised as regular medicine, methods of use, journals, etc. I'd go as far as accusing the user WLU of vandalism for the series of edits on 4 October. I'll tag the article as not neutral.

1114:. Although ozone is used in a complementary capacity by a significant number of doctors in Italy, Switzerland, Austria and Germany, it has still not gained popular support with mainstream industry policy makers in those countries, it is not covered by 2964:

In vitro and in vivo studies of the long-term antioxidant capacity of infiltration with O2-O3 gas mixture in the human body show that it binds immediately to water and cell membrane components like Poly Unsaturated Fatty Acids (PUFA).(Noel L.Smith et

2371:

2017 study: Ozone insufflation led to significantly increased antioxidant enzymes and cellular reduced glutathione; decreased oxidation damage; and decreased levels of pro-inflammatory cytokines TNFα and IL-1β. Stimulated CK2 expression and the Nrf2

2089:

GERMAN, I. J. S.; RODRIGUES, A. C.; ANDREO, J. C.; POMINI, K. T.; AHMED, F. J.; BUCHAIM, D. V.; ROSA JòNIOR, G. M.; GONALVES, J. B. O. & BUCHAIM, R. L. Ozone therapy in dentistry: A systematic review. Int. J. Odontostomat., 7(2):267-278, 2013.-

1813:

This does not appear to be pubmed indexed "This statement is opposed with the release of a peer-reviewed publication (2016), which performed a systematic review of controlled human trials of two major forms of systemic ozone therapies. Based on the

729:"Despite the presently compelling evidence, future studies should include more double-blind, randomized clinical trials with greater sample sizes, determination of longevity in benefits produced, as well as methods of measurements and analysis." 2363:

2018 Chinese study comparing 30 patients treated with ozone therapy vs 30 patients treated with valacyclovir, mupirocin ointment and laser treatment: all the ozone group recovered (vs only 87% of control group), and did so faster and with less

2104:

Pain Physician. 2012 Mar-Apr;15(2):E115-29, Ozone therapy as a treatment for low back pain secondary to herniated disc: a systematic review and meta-analysis of randomized controlled trials. Magalhaes FN1, Dotta L, Sasse A, Teixera MJ, Fonoff

3203:

In the blood, in case of a sepsis (microbial infection of the blood) for example, as ozone binds too fast to water, available proteins and PUFA and because of the small dosage used, ozone will not be sufficient to act as an antipathogen.

485:, a collaborative effort to improve Knowledge's coverage of significant alternative views in every field, from the sciences to the humanities. If you would like to participate, please visit the project page, where you can join the 2872:

When the ozone reaches the body cells there are two important reaction chains. Ozone will be reacting with the membrane phospholipids and thus produce the following products: Ozonides, Aldehydes, Peroxide, and Hydrogen peroxide.

2376:

Some of these studies are not double blinded, randomized, controlled studies, and some are not published in ideal peer reviewed conditions. They do not constitute proof, and may be open to dispute, but they are "some evidence".

1272:

Very little of this article is about Ozone therapy. If someone wants to read about chemical properties of ozone, we have the article for it. I will be deleting the material that is not about "Ozone therapy" and leave a link for

895:

I can't believe I'm being bullied on Knowledge. You took out that fragment which was verifiably accurate, noticed my non-combat, and then you came back to make it clear that you're happy everything worked the way you forced

3073:

The importance of this is that after the immediate oxidative effect, antioxidant mechanisms are stimulated and after repetitive stimulation the antioxidant mechanisms remain active at a higher grade. (Viebahn, Malatesta,

3123:

Secondly low dose ozonised blood enhances blood circulation and oxygen delivery to ischemic tissues as a result of the concerted effect of NO and CO and an increase in intraerythrocytic 2,3 diphosphoglycerate (2,3 DPG).

2854:

The conclusion here is in order to be safe Ozone needs to be administered in low dosages avoiding pulmonary inhalation, by different application methods via tissues that have sufficient antioxidants available, including

1349:

article or any other related to ozone therapy I will ask first discussing in the respective talk page. Sorry if my English is not good, it is not my first language. I hope that together we can improve this article. --

2561:

Started 2020-02-22, Haihe Hospital, Tianjin. Non-random controlled. 15 mild ill and 15 severe or critical ill patients receive conventional treatment plus ozonated autohaemotherapy; 30 controls receive conventional

1877:"Ozone in Medicine: Clinical Evaluation and Evidence Classification of the Systemic Ozone Applications, Major Autohemotherapy and Rectal Insufflation, According to the Requirements for Evidence-Based Medicine" 1510:

At least 10 deaths have been related to ozone therapy or its lack of usefulness, in nine cases there had been investigation and in eight it was discovered that the practitioners had used false credentials.

135: 150: 2142:

As previously stated many years ago, the language and tone of this article is very clearly anti-ozone therapy. Knowledge should be a place of neutrality to allow readers to form their own opinions.

2956:

Low dosages, though, can activate antioxidant pathways. In other words, low dosage of Ozone activates the homeostasis mechanism in the body to prevent oxidation and damage of cells and structure.

945:

few that you have chosen. To use quackwatch, Ernst, certain physicians who have written for quackwatch, etc. is the definition of using BIAS in an article. The article needs to be flagged.

3476:

Not very helpful I'm afraid, and nobody will be making any changes to the article based on this TL;DR screed. Which, if any, of the refs you have wedged in meet our sourcing requirements

3188:

O2-O3 mixture is known in industry for its strong antibacterial, antifungal and antiviral action in disinfecting water, materials, and spaces. In ozone therapy nevertheless this effect

2445: 2343:

2012 Review of 3 prior studies, and preliminary results of combined ozone and interferon therapy. Patients treated with ozone therapy have a 40% relapse rate one year after treatment.

1917:

peer review process giving priority to articles that improve clinical decision-making in general medicine. BMJ Case Rep is owned by BMJ. BMJ is one the world top medical journals.

1761:" As it has happened for other innovative medical approaches, thanks for the efforts of many expert physicians, ozone therapy will be eventually accepted by orthodox medicine." 323: 692:

The article previously stated that Joseph Lloyd Martin discovered ozone. This is inconsistent with what I have found in other reputable references and what is stated in the

171: 3970: 3960: 520: 510: 3078:

Galiè, Mirco; Costanzo, Manuela; Nodari, Alice; Boschi, Federico; Calderan, Laura; Mannucci, Silvia; Covi, Viviana; Tabaracci, Gabriele; Malatesta, Manuela (2018-08-20).

2860:

Administration via different routes than inhalation can encompass immune system activation, vascular and haematological modulation and increase of anti-oxidant activity.

327: 1566:

It is fine to contest the strength of the references, but you need to remember respond to talk page discussions before reverting edits without sufficient elaboration.

2711:

There is no ozone therapy, there is ozone poisoning. Ozone is a poison. It is very good that there is ozone at high altitudes, but we would not like to breathe ozone.

1206: 3975: 3965: 2637: 474: 419: 2283:(2018 review found few and poor-quality studies in support of lumbar pain relief. This review is useful in discussing minor but potentially serious complications) 1532:

Both articles are included on pubmed. The journal is less mainstream, but the methodology and contentions are clear. Need further elaboration to justify removal.

2548:

linked in his edit summary, and am much chastened. I may continue to add notes to the talk page, such as the five clinical trials I've found currently underway:

1170:

Ikonomidis et al., New Data Regarding The Use Of Ozone Therapy In The Former Soviet Union Countries. Rivista Italiana di Ossigeno-Ozonoterapia 4 (1): 40-43, 2005

3588:

TABLE 1 THERAPEUTIC INDICATIONS (Burns, Smith 2017, Linee Guida e Buone Pratiche in Ossigeno Ozono terapia art. 6-L. 8 marzo 2017 n.24, Zambello, Bonetti et al)

832:. If you want to make accusations of vandalism, take them somewhere else and provide plenty of evidence. Otherwise, such accusations are disruptive and incivil. 486: 1552:

and don't try and force stuff in sourced to weak sources. You have been warned for edit-warring. Be aware this topic is subject to discretionary sanctions.

3985: 753:

One might also be interested in posting the following diagram recently published by Harvard Medical School researchers, with Ozone gas (O3) at top center:

621: 611: 2518:, and that if we wait, we can put truly solid information in. I'd rather that we got this right, even if that means waiting months until proper medical 410: 390: 79: 3950: 1819: 367: 357: 2785:

Bocci, Velio; Borrelli, Emma; Travagli, Valter; Zanardi, Iacopo (07-2009). "The ozone paradox: ozone is a strong oxidant as well as a medical drug".

780:

Clearly this is a very biased article written by opponents. There is no suggestion of neutrality in the way it is written. It needs to be tagged.

184: 3990: 3980: 2773:

Inhalation of oxygen: Ozone being a very potent oxidant harms the lungs irritating the mucous membranes of the lungs to result in pulmonary oedema.

2407:

a number of trials showing interesting results but that no rigorous trials on humans have yet shown positive effect and hence it remains unproven.

2148:

Moreover, some the website sources used to promote the writer's skewed point of view are dangerously unqualified and smacks of yellow journalism.

1674:

As this is fringe medicine, there is not much "accepted knowledge" about it. There is no angle, simply responding to your criticism. Thanks again.

3955: 2254:(Ozone therapy effective in pain relief for osteoarthritis of the knee: review article including 8 studies, 355 patients treated and 363 controls) 481: 458: 3053:

The presence of hydrogen peroxide and the lipid ozonation products increase activation of the Nuclear Factor Erythroid 2-related Factor 2 (Nrf2).

3120:

The presence of O3 causes an increase of efficiency of oxygen delivery to the cells. The mitochondrial respiratory chain is made more efficient.

3945: 3446: 3295: 3033: 2935: 2660:

Why is the empirical research supporting ozone missing? A simple google pulled up NIH data that supports the efficacy of ozone for health uses

1380: 1354: 587: 85: 44: 2160: 2124: 2106: 2091: 2075: 2045: 2014: 1992: 1950: 1660:

No, "novel" in respect of accepted knowledge. I have no "feelings" about this topic and it is inappropriate for you to try for that angle.

766: 738: 2588:

But I understand WP guidelines on levels of medical evidence better now, and am in no hurry to add any more on this to the article proper.

2681:

That is not "NIH data". That is an article from the "Journal of natural science, biology, and medicine" which happens to be included in

2667: 2614: 332: 2403:

words or liberal sprinkling of adjectives such as "unproven", "discredited" into every second sentence as scare flags for the reader.

1787:

source you come across that actually uses the term "big Pharma" in a serious, pejorative sense can be safely dismissed as unreliable.

2151:

Articles and writers such as this one should be outlawed from wikipedia. It is ridiculous that it has remained this way for so long.

1147:

Jacobs et al., Untersuchung Über Zwischenfalle Und Typische Komplikationen In Der Ozon-Sauerstoff-Therapie. Ozo Nachrichten 1982; 1:5

1768: 946: 1157: 3045:

After contact with water (H2O), Hydrogen Peroxide is formed and after contact with the PUFA Lipid Ozonation products are formed.

1376: 1350: 697: 566: 543: 2879:"Ozone in Medicine. The Low-Dose Ozone Concept and Its Basic Biochemical Mechanisms of Action in Chronic Inflammatory Diseases" 1837: 870: 99: 30: 3442: 3291: 3029: 2931: 2613:

An in-depth debate on this topic has been ongoing for several days now. To access its interactive content, simply click on →

2515: 318: 279: 104: 20: 2953:

Ozone is a potent oxidant. High dosages cause high oxidative stress and eventual inflammation and even damage to the tissue.

1439: 1241: 74: 2702: 835:

I agree that it is worth trying to salvage some information on its use if we can agree on the sources and don't confound

2739: 1732: 1679: 1651: 1607: 1571: 1537: 1394:

Is this theory "mainstream enough" that it can be called "alternative medicine" without being called a "fringe theory?"

662: 254: 213: 1602:, and to respond to editors questions when reverting before starting something that could be perceived as an edit war. 3853: 3455: 1841: 1494: 1339: 1257: 65: 2263: 755:

Medical Gas Therapy for Tissue, Organ, and CNS Protection: A Systematic Review of Effects, Mechanisms, and Challenges

586:

related articles on Knowledge. If you would like to participate, please visit the project page, where you can join

418:

related articles on Knowledge. If you would like to participate, please visit the project page, where you can join

208: 3216:

Also, it is now proven that cytokines are directly stimulated by Ozone in fibroblasts and leucocytes. (Malatesta)

2277:(2019 review including 6 trials found ozone therapy more effective than steroids or placebo, with low confidence) 1443: 2314:(2018 study: 28 patients all had viral load and biological markers reduce to undetectable levels within 15 days) 672: 222: 3200:

vaginal dysbiosis, after which the good bacterial flora has to be re-established with micro biotic supplements.

1420:

template is sufficient or if adding "fringe theories" improves the encyclopedia, I'm asking that this template

1401: 191: 126: 2510:

idea before? It can be very tempting for editors to rush forward, even though nothing's really known, to add

2164: 2128: 2110: 2095: 2079: 2049: 2018: 1996: 1954: 770: 742: 242: 2671: 810: 1728: 1675: 1647: 1603: 1567: 1533: 109: 2522:(NB: not case studies, like "We tried this on these two patients, and they recovered") to get published. 1772: 950: 3849: 3577:

A= Shown statistically relevant evidence in Systematic Reviews (SR) of Randomised Controlled Trials (RCT).

3552: 3520: 3487: 3451: 2649: 2527: 1796: 1490: 1335: 1253: 1224: 1410:

Since I'm on the fence here and I expect that there won't be universal agreement on whether the existing

3436: 3346: 3271: 3163: 3023: 2925: 2820: 2698: 2497: 2430: 2288:

Ozone therapy effective treatment for herniated discs in terms of pain, function and complication rate:

1200: 1068: 1009: 993: 260: 2781:

get a chance to enhance antioxidant mechanisms as when it comes into contact with blood, water or PUFA.

2583:

depending on severity of disease, plus conventional treatment. Controls receive conventional treatment.

2229: 3583:

C = Expert opinion without explicit critical appraisal or based on physiology bench research. ( OCEBM)

2493: 2426: 3916: 3536: 3079: 2732: 2716: 2156: 2071: 1946: 1764: 1309: 1282: 1049: 976: 858: 734: 415: 198: 3128:

Bocci, Velio (2012-09). "How a calculated oxidative stress can yield multiple therapeutic effects".

1822:(2009) criteria, systemic medical ozone therapy is establishing itself as evidence-based medicine." 2507: 2340: 2202: 1943:

May I ask why one of the world top medical journals is considered by you "not a reliable source"?

1833: 1064: 1005: 963:. Some alt-med journals exist for the sole reason of bolstering quackery. QuackWatch and Ernst are 901: 866: 819: 785: 731:(Med Gas Res. 2017 Oct 17;7(3):212-219. doi: 10.4103/2045-9912.215752. eCollection 2017 Jul-Sep.) 55: 3382:

Smith, Noel L.; Wilson, Anthony L.; Gandhi, Jason; Vatsia, Sohrab; Khan, Sardar Ali (2017-10-17).

2969:

Smith, Noel L.; Wilson, Anthony L.; Gandhi, Jason; Vatsia, Sohrab; Khan, Sardar Ali (2017-10-17).

2225: 1292:

MEDRS source British Medical Source removed and replaced by offtopic random statements about ozone

2596: 2475: 2456: 2415: 2381: 2206: 1969: 1599: 1519: 960: 709: 678: 227: 70: 2331:: 2011 preliminary study: symptoms improve and 25-45% of patients test negative for RNA in serum 2506:

Please don't add any information about COVID-19 to this article yet. Have you heard about the

2280: 2274: 2257: 2123:. Ozone therapy for lumbosciatic pain* José Oswaldo de Oliveira Junior; Gustavo Veloso Lages -- 1475: 1043: 1025: 3546: 3515: 3481: 3419: 3403: 3335: 3328: 3260: 3244: 3152: 3145: 3099: 3006: 2990: 2914: 2898: 2809: 2802: 2640: 2523: 2289: 2192: 2034: 2007: 1977: 1930: 1896: 1789: 1717: 1665: 1633: 1589: 1557: 1435: 1237: 1189: 51: 2368: 2360: 2334: 2328: 2317: 2303: 2251: 177: 3410: 3395: 3320: 3251: 3236: 3137: 3091: 2997: 2982: 2905: 2890: 2794: 2720: 2694: 2400: 2296: 2184: 2062: 1888: 1815: 1549: 1115: 989: 968: 674: 643: 558: 537: 224: 3911:

allowed, specifically rendering the EBM consensus in sources published e.g. by AMA or WHO.

3688:

Entrapment syndrome of the lateral cutaneous nerve of the thigh (Bernhardt-Roth Syndrome)

1032:

Because ozone is a natural substance, pharmco will not endorse it as they cannot patent it.

3912: 3901: 3882: 3532: 3477: 3371: 3359: 3284: 3176: 3080:"Mild ozonisation activates antioxidant cell response by the Keap1/Nrf2 dependent pathway" 2845: 2833: 2712: 2686: 2541: 2351: 2311: 2271:

Ozone therapy effective for lumbar pain relief (few and poor-quality studies in support):

2180: 1965: 1922: 1545: 1372: 1327: 1305: 1300: 1278: 1111: 1083: 972: 836: 310: 1252:

Yes, as in modern medicine, ozone is not used, and the FDA treats it as a pseudoscience.

811:

https://secure.wikimedia.org/wikipedia/en/search/?title=Ozone_therapy&oldid=453926959

3384:"Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility" 3383: 3095: 2971:"Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility" 2970: 2664: 2145:

Please present the pro and cons side by side and let the reader decide his or her view.

2119:

Revista Dor Print version ISSN 1806-0013 Rev. dor vol.13 no.3 São Paulo July/Sept. 2012

2065: 1753: 1748: 1061: 701: 3414: 3255: 3224: 3001: 2909: 2878: 2754: 2682: 2519: 2488:

Ibiza institution. I’m more than happy to be corrected (it wouldn’t be the first time).

2337:

2009 Russian language study found ozone therapy more effective than standard treatments

2176: 1825: 1709: 1095: 1087: 1035: 964: 923: 897: 886: 862: 844: 815: 800: 781: 762: 758: 723:

A neutral viewpoint would include much better balance, such as the following excerpt:

473: 452: 2449: 1489:

These are all pro-ozone therapy articles, which gives undue weight to fringe science.

3939: 3524: 2621: 2593: 2472: 2453: 2412: 2378: 2295:

Ozone therapy effective for treatment of chronic wounds (healing and wound closure):

2120: 1625: 1617: 1581: 1516: 1038:

is a natural constituent of willow tree bark and that didn't prevent Bayer patenting

1024:

By whom? By accredited medical professionals/associations? Please be more concise. --

915: 911: 829: 705: 579: 575: 24: 3574:

The grade of evidence according to the standard of Evidence Based Medicine (EBM) are

2558: 3711:

Knee, Hip, Shoulder or Elbow Arthrosis (GRADE A for the knee (Raeissadat), GRADE B)

3528: 2545: 2468: 2396: 2188: 2030: 1973: 1926: 1876: 1713: 1661: 1643: 1629: 1585: 1553: 1428: 1414: 1230: 2572: 2565: 2551: 2264:

https://www.sciencedirect.com/science/article/abs/pii/S0965229918307337?via%3Dihub

1892: 1480: 165: 3225:"The Role of Nrf2 in the Antioxidant Cellular Response to Medical Ozone Exposure" 3141: 2044:

Thank you very much, I will try to search a systematic review in a top journal.--

3223:

Galiè, Mirco; Covi, Viviana; Tabaracci, Gabriele; Malatesta, Manuela (2019-08).

402: 384: 2514:

about the big news topic. But it's better in these instances to remember that

2471:, and I think it needs clarifying, with supporting citation, or else removing. 1875:

Viebahn-Hänsler, Renate; Fernández, Olga Sonia León; Fahmy, Ziad (2016-09-02).

3324: 1470:

The following websites might help to contribute in “Safety” of ozone therapy.

583: 300: 3682:

External popliteal sciatic nerve or common peroneal nerve entrapment syndrome

3406: 3399: 3331: 3247: 3148: 3102: 2993: 2986: 2901: 2805: 2576:

gas containing 40 μg/mL ozone). Controls receive standard hospital treatment.

2061:

J Nat Sci Biol Med. 2011 Jan-Jun; 2(1): 66–70. doi: 10.4103/0976-9668.82319

1899: 2411:

agenda here, merely trying to achieve accuracy and a neutral point of view.

1862: 1091: 1082:

Seems to confuse health claims, use, and efficacy. Basically, there are the

919: 882: 840: 796: 3896:

While technically some systematic reviews which aren't indexed for MEDLINE

3571:

The following table 1 shows the therapeutic indications for ozone therapy.

3422: 3338: 3263: 3155: 3009: 2917: 2812: 2777:

surfactant and phospholipids, the so called Endothelial Lining Fluid (ELF).

2260:(review article including 5 studies, 225 patients treated and 203 controls) 2010: 1192: 3670:

Deep Peroneal Nerve Entrapment Syndrome (Anterior Tarsal Tunnel Syndrome)

3240: 2894: 1598:

Thanks for clarifying. My suggestion to you is to please try to remember

1022:

I've attended Ozone conferences in Europe, where they are very accepted.

676: 226: 125: 2690: 1039: 571: 3920: 3857: 3557: 3540: 3492: 3459: 3058:

Which results in the expression of Antioxidant Response Elements (ARE)

2798: 2675: 2653: 2626: 2599: 2531: 2501: 2478: 2459: 2434: 2418: 2384: 2248:

Ozone therapy found effective for pain relief in knee osteoarthritis:

2233: 2210: 2196: 2168: 2132: 2114: 2099: 2083: 2068:

Ozone therapy: A clinical review, authors A. M. Elvis and J. S. Ekta

2053: 2038: 2022: 2000: 1981: 1958: 1934: 1845: 1802: 1776: 1736: 1721: 1683: 1669: 1655: 1637: 1611: 1593: 1575: 1561: 1522: 1498: 1459: 1449: 1384: 1358: 1343: 1313: 1286: 1261: 1246: 1099: 1072: 1053: 1013: 997: 980: 954: 927: 905: 890: 874: 848: 823: 804: 789: 774: 746: 713: 3617:

Pain after back surgery FBSS of the cervical, dorsal and lumbar spine

1371:

Hello. I found two metaanalysis of discolysis. Please discuss in the

1134: 1090:

issues that might be addressed with rewording and better sources: --

3900:

be accepted (if published in very reputable journals), in light of

3580:

B =Systemic Reviews of Case Control (Individual or Cohort) studies.

2877:

Viebahn-Haensler, Renate; León Fernández, Olga Sonia (2021-07-23).

1642:

Ok thank you. Incidentally, if by "novel" you are trying to invoke

1616:

My advice to you is to get some basic understanding of Knowledge's

294: 273: 2579: 1274: 986:

Ernst is an expert in nothing but asking others to prove negatives

693: 2738:

This user is aware of the designation of the following topics as

700:). The reference for this (which was not properly linked is here 3694:

Interdigital nerve entrapment syndrome (Civinini-Morton neuroma)

2341:

https://www.tandfonline.com/doi/abs/10.1080/01919512.2012.720161

2244:

the article. (I'll add these to the below list as I find them.)

330:. Please visit the project page for details or ask questions at 3042:

Hydrogen Peroxide (OH-) and Lipidoxidation products are formed.

141: 3623:

Spinal canal Stenosis of the cervical, dorsal and lumbar spine

3565:

the sourcing requirements WP: MEDRS. That will take some time.

2727: 2638:

Knowledge talk:WikiProject Medicine/Archive 138#Johann Lahodny

679: 637: 236: 228: 15: 322:, which recommends that medicine-related articles follow the 2320:(2008 Chinese-language study on 20 patients plus 22 control) 2281:

https://pesquisa.bvsalud.org/portal/resource/pt/mdl-30414366

2275:

https://pesquisa.bvsalud.org/portal/resource/pt/mdl-31521383

2258:

https://pesquisa.bvsalud.org/portal/resource/pt/mdl-30498370

2290:

https://www.jvir.org/article/S1051-0443(09)01668-6/fulltext

1135:"European Cooperation of Medical Ozone Societies, web site" 809:

Actually it is clearly not neutral. Please look at version

3191:

is mostly of use in direct application of O2-O3 mixture to

3050:

This activates Nuclear Factor Erythroid 2 related Factor 2

2961:

Low concentration Ozone comes in contact with H2O and PUFA

2369:

https://www.ncbi.nlm.nih.gov/pubmed/28623000?dopt=Abstract

2361:

https://www.ncbi.nlm.nih.gov/pubmed/29559601?dopt=Abstract

2335:

https://www.ncbi.nlm.nih.gov/pubmed/21417811?dopt=Abstract

2329:

https://www.ncbi.nlm.nih.gov/pubmed/21417811?dopt=Abstract

2318:

https://www.ncbi.nlm.nih.gov/pubmed/19544653?dopt=Abstract

2304:

https://www.ncbi.nlm.nih.gov/pubmed/31584525?dopt=Abstract

2292:(metaanalysis of 12 studies covering nearly 8000 patients) 2252:

https://onlinelibrary.wiley.com/doi/abs/10.1002/pmrj.12088

2348:

HIV: Ozone in conjunction with antiretroviral treatment:

2297:

https://onlinelibrary.wiley.com/doi/abs/10.1111/iwj.12907

1180:

Madej P, Antoszewski Z, Madej JA (1995). "Ozonotherapy".

727:

As well as the following, from the same published review

149: 3646:

Ulnar Nerve Entrapment Syndrome (Cubital Canal Syndrome)

3640:

Ulnar Nerve Entrapment Syndrome (Guyon’s Canal Syndrome)

3611:

Osteoarthritis of the cervical, dorsal and lumbar spine

3605:

Herniated disc of the cervical, dorsal and lumbar spine

2352:

https://ojs.uv.es/index.php/JO3T/article/view/11458/pdf

2312:

https://ojs.uv.es/index.php/JO3T/article/view/11459/pdf

2302:

Intralesional ozone injection effective against warts:

1708:

FYI, I have initiated a discussion about this topic at

1296: 1818:(1992) evidence classification system, as well as the 3599:

Bulging disc of the cervical, dorsal and lumbar spine

2665:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312702/

1062:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312702/

702:

http://www.homeoint.org/history/cleave/m/martinjl.htm

3185:

Pathogen inactivation of bacteria fungi and viruses.

2224:

saying ozone isn’t effective. This is embarrassing.

570:, a collaborative effort to improve the coverage of 414:, a collaborative effort to improve the coverage of 1506:I've removed the following sentence from the lede: 1455:Agree that currently it's fringe. will add tag. -- 3634:Nerve Entrapment Syndrome (Carpal Tunnel Syndrome) 2559:http://www.chictr.org.cn/showproj.aspx?proj=49947 2444:appraisal, which falls of a very low rung on the 2325:Ozone therapy effective for chronic Hepatitis C: 2138:This Article is STILL biased and must be revised. 2121:http://dx.doi.org/10.1590/S1806-00132012000300012 2687:reliable enough for writing about medical topics 33:for general discussion of the article's subject. 2945:oxygenase 1 and Heat Shock Protein 70 (HSP-70). 2573:https://clinicaltrials.gov/ct2/show/NCT04370223 2566:https://clinicaltrials.gov/ct2/show/NCT04359303 2552:https://clinicaltrials.gov/ct2/show/NCT04366089 1584:above all. You were edit warring against them. 326:and that biomedical information in any article 3676:Superficial Peroneal Nerve Entrapment Syndrome 1754:Mechanisms of Action Involved in Ozone Therapy 1424:be added until after discussion has occurred. 1268:Very little of this article is about the topic 1060:This entry appears to be outdated and biased. 2685:. We have no reason to think that journal is 2308:Ozone therapy effective against Hepatitis B: 324:Manual of Style for medicine-related articles 197: 157: 8: 1205:: CS1 maint: multiple names: authors list ( 881:It's not vandalism. Glad we're past that. -- 3705:Trapeziometacarpal Arthrosis (Rizarthrosis) 3229:International journal of molecular sciences 2883:International Journal of Molecular Sciences 1407:should be added to the top of the article. 240: 3763:Diabetic foot ulcers (Anupunpisit) GRADE A 3652:Posterior Tibial Nerve Entrapment Syndrome 2266:(2019 review article including 10 studies) 2154: 2069: 1944: 1762: 1481:Ozone Theraphy_Dentistry with a conscience 1158:"German Law Embraces Alternative Medicine" 839:issues with those of marketing and use. -- 732: 532: 447: 428:Knowledge:WikiProject Alternative medicine 379: 268: 3971:Low-importance Alternative Views articles 3961:Start-Class Alternative medicine articles 3729:VARIOUS GENERALIZED DEGENERATIVE DISEASES 3413: 3254: 3000: 2908: 1820:Oxford Center for Evidence Based-Medicine 431:Template:WikiProject Alternative medicine 2299:(2018 review of 9 studies, 453 patients) 2058:I suggest following systematic reviews: 1624:trying to force novel content in. Maybe 1277:for those interested in its properties. 696:article (i.e. that it was discovered by 1855: 1126: 534: 495:Knowledge:WikiProject Alternative Views 449: 381: 270: 3976:WikiProject Alternative Views articles 3966:Start-Class Alternative Views articles 3717:Knee, Hip, Shoulder or Elbow Synovitis 3434: 3367: 3355: 3344: 3280: 3269: 3172: 3161: 3117:Vascular and haematological modulation 3021: 2923: 2841: 2829: 2818: 1326:I agree with Yobol that this is not a 1198: 985: 498:Template:WikiProject Alternative Views 2006:Spine (Phila Pa 1976). 2013 Dec 30. 914:if you have any interest in changing 183: 7: 3907:Do mind that higher quality sources 2555:hydroxychloroquine and antibiotics.) 564:This article is within the scope of 479:This article is within the scope of 408:This article is within the scope of 316:This article is within the scope of 3096:10.1016/j.freeradbiomed.2018.05.093 959:I agree the article is biased, see 333:Knowledge talk:WikiProject Medicine 259:It is of interest to the following 23:for discussing improvements to the 3986:Mid-importance Skepticism articles 14: 3798:ALS Amyotrophic Lateral Sclerosis 3523:was warned that her next edit to 3445:) CS1 maint: unflagged free DOI ( 3294:) CS1 maint: unflagged free DOI ( 3084:Free Radical Biology and Medicine 3032:) CS1 maint: unflagged free DOI ( 2934:) CS1 maint: unflagged free DOI ( 2219:Reference supports opposite claim 3951:Low-importance medicine articles 3734:Therapeutic Indications GRADE C 2731: 1881:Ozone: Science & Engineering 1749:Ozone therapy: A clinical review 1223:Should this article be added to 988:This is just random bullshit. -- 971:, which is a content guideline. 642: 596:Knowledge:WikiProject Skepticism 557: 536: 472: 451: 411:WikiProject Alternative medicine 401: 383: 328:use high-quality medical sources 303: 293: 272: 241: 45:Click here to start a new topic. 3991:WikiProject Skepticism articles 3981:Start-Class Skepticism articles 3664:Sural Nerve Entrapment Syndrome 3658:(Medial Tarsal Tunnel Syndrome) 2580:https://www.irct.ir/trial/47149 2239:Evidence of safety and efficacy 1160:. New Scientist Magazine, 1997. 616:This article has been rated as 599:Template:WikiProject Skepticism 515:This article has been rated as 362:This article has been rated as 3956:All WikiProject Medicine pages 3313:Nature reviews. Drug discovery 2676:14:07, 25 September 2022 (UTC) 2516:Knowledge:There is no deadline 1528:Reversion of safety discussion 1460:20:55, 12 September 2013 (UTC) 1367:Discolysis article improvement 1086:issues with health claims, vs 1014:20:45, 12 September 2013 (UTC) 342:Knowledge:WikiProject Medicine 1: 3946:Start-Class medicine articles 3332:1474-1776 1474-1784 1474-1776 2950:Ozone’s antioxidant capacity. 2806:0198-6325 1098-1128 0198-6325 2133:02:53, 25 December 2016 (UTC) 2115:02:51, 25 December 2016 (UTC) 2100:02:48, 25 December 2016 (UTC) 2084:15:50, 24 December 2016 (UTC) 2054:16:30, 17 December 2016 (UTC) 2039:16:26, 17 December 2016 (UTC) 2023:16:16, 17 December 2016 (UTC) 2001:16:07, 17 December 2016 (UTC) 1982:16:04, 17 December 2016 (UTC) 1959:16:02, 17 December 2016 (UTC) 1935:15:59, 17 December 2016 (UTC) 1893:10.1080/01919512.2016.1191992 1385:19:21, 15 December 2012 (UTC) 1359:03:01, 10 December 2012 (UTC) 1314:06:22, 25 November 2012 (UTC) 1287:04:12, 25 November 2012 (UTC) 1100:18:41, 29 December 2011 (UTC) 998:06:21, 1 September 2023 (UTC) 981:00:16, 1 September 2023 (UTC) 891:17:26, 30 December 2011 (UTC) 875:11:01, 30 December 2011 (UTC) 849:18:52, 29 December 2011 (UTC) 824:08:38, 29 December 2011 (UTC) 805:17:02, 24 December 2011 (UTC) 790:01:14, 24 December 2011 (UTC) 698:Christian Friedrich Schönbein 590:and see a list of open tasks. 482:WikiProject Alternative views 434:Alternative medicine articles 422:and see a list of open tasks. 345:Template:WikiProject Medicine 42:Put new text under old text. 3751:Ulcers due to Vasculopathies 3142:10.3109/10715762.2012.693609 3062:driven genes can be induced. 1344:06:21, 4 December 2012 (UTC) 1247:17:19, 13 January 2012 (UTC) 1073:03:06, 11 January 2019 (UTC) 1054:17:33, 26 October 2013 (UTC) 928:17:33, 21 January 2012 (UTC) 906:12:00, 21 January 2012 (UTC) 3904:it is not such a good idea. 3885:sets forth two conditions: 3213:element (ARE) driven genes. 1846:03:00, 14 August 2016 (UTC) 1803:17:36, 9 October 2016 (UTC) 1777:19:30, 8 October 2016 (UTC) 955:19:12, 31 August 2023 (UTC) 50:New to Knowledge? Welcome! 4007: 3723:Retropatellar chondropathy 3629:NERVE ENTRAPMENT SYNDROMES 3441:: CS1 maint: PMC format ( 3028:: CS1 maint: PMC format ( 2930:: CS1 maint: PMC format ( 2787:Medicinal research reviews 2721:17:32, 24 March 2023 (UTC) 2654:05:19, 4 August 2020 (UTC) 2532:15:52, 28 April 2020 (UTC) 2502:02:41, 28 April 2020 (UTC) 2479:00:00, 28 April 2020 (UTC) 2460:23:47, 27 April 2020 (UTC) 2435:19:48, 27 April 2020 (UTC) 2419:15:58, 27 April 2020 (UTC) 2385:06:16, 27 April 2020 (UTC) 2234:22:54, 13 March 2020 (UTC) 1737:20:17, 25 April 2016 (UTC) 1722:20:11, 25 April 2016 (UTC) 1684:20:13, 25 April 2016 (UTC) 1670:20:07, 25 April 2016 (UTC) 1656:19:31, 25 April 2016 (UTC) 1638:19:18, 25 April 2016 (UTC) 1612:19:14, 25 April 2016 (UTC) 1594:19:09, 25 April 2016 (UTC) 1576:19:07, 25 April 2016 (UTC) 1562:19:05, 25 April 2016 (UTC) 1523:23:46, 29 March 2020 (UTC) 1499:21:24, 25 April 2016 (UTC) 1397:If the answer is no, then 1262:21:21, 25 April 2016 (UTC) 622:project's importance scale 521:project's importance scale 501:Alternative Views articles 368:project's importance scale 3921:21:48, 9 April 2023 (UTC) 3858:20:53, 9 April 2023 (UTC) 3739:Peripheral Vasculopathies 3558:20:55, 9 April 2023 (UTC) 3541:20:27, 9 April 2023 (UTC) 3493:20:04, 9 April 2023 (UTC) 3460:17:36, 9 April 2023 (UTC) 3325:10.1038/s41573-018-0008-x 2703:17:37, 6 March 2023 (UTC) 2627:20:50, 13 July 2020 (UTC) 2446:scale of medical evidence 1865:(What's The Harm website) 1580:Knowledge editors follow 1450:20:44, 11 June 2013 (UTC) 775:15:59, 26 July 2022 (UTC) 747:15:42, 26 July 2022 (UTC) 714:17:22, 13 July 2011 (UTC) 615: 552: 514: 467: 396: 361: 288: 267: 80:Be welcoming to newcomers 3827:Ulcerative recto colitis 3757:Pressure sores Decubitus 3400:10.4103/2045-9912.215752 3209:Immune system activation 2987:10.4103/2045-9912.215752 2211:10:33, 6 July 2017 (UTC) 2197:06:32, 6 July 2017 (UTC) 2169:22:30, 5 July 2017 (UTC) 1972:for further background. 1105:Mainstream medicine uses 3888:systematic reviews, and 3700:ARTHROSIS AND SYNOVITIS 3568:Therapeutic Indications 3305:pathological features. 3290:CS1 maint: PMC format ( 2689:. It is not indexed in 2636:Discussion archived at 2600:06:39, 4 May 2020 (UTC) 1390:Is this a fringe theory 1319:Madrid declaration link 1304:o MEDRS grounds alone. 1299:edit was made removed 757:(PMID: 35243825 PMCID: 663:Start to December, 2010 3366:Check date values in: 3279:Check date values in: 3171:Check date values in: 2840:Check date values in: 2540:Thank-you. I read the 1225:Category:Pseudoscience 1034:Statement is dubious, 763:10.1002/advs.202104136 567:WikiProject Skepticism 249:This article is rated 75:avoid personal attacks 3596:Grade of evidence EBM 3130:Free radical research 1991:Thank you very much-- 1798:Tell me all about it. 1743:Additional References 123:Find medical sources: 100:Neutral point of view 3891:indexed for MEDLINE. 3821:Rheumatoid Arthritis 3388:Medical Gas Research 3241:10.3390/ijms20164009 2975:Medical Gas Research 2895:10.3390/ijms22157890 2367:Multiple sclerosis: 795:Not clear at all. -- 425:Alternative medicine 416:Alternative medicine 391:Alternative medicine 319:WikiProject Medicine 105:No original research 2863:Mechanism of Action 2606:Ozone therapy — OHT 2508:Knowledge:Recentism 602:Skepticism articles 3803:Parkinsons Disease 3792:Multiple Sclerosis 3786:Vascular Headaches 2873:(Viebahn-Haensler) 2757: 2740:contentious topics 1727:Much appreciated. 1600:Knowledge:Civility 1476:Why Ozone Therapy? 688:Discovery of ozone 255:content assessment 129: 86:dispute resolution 47: 3850:Hermelyn Meinardi 3527:will take her to 3521:Hermelyn Meinardi 3452:Hermelyn Meinardi 3197:rectal dysbiosis, 2799:10.1002/med.20150 2762: 2761: 2748: 2630: 2610:Hello everyone, 2469:original research 2171: 2159:comment added by 2086: 2074:comment added by 1961: 1949:comment added by 1799: 1779: 1767:comment added by 1491:ThePlatypusofDoom 1448: 1447: 1336:UseTheCommandLine 1254:ThePlatypusofDoom 878: 861:comment added by 765:Free PMC article 749: 737:comment added by 685: 684: 636: 635: 632: 631: 628: 627: 531: 530: 527: 526: 492:Alternative Views 459:Alternative Views 446: 445: 442: 441: 378: 377: 374: 373: 348:medicine articles 235: 234: 128:Source guidelines 127: 66:Assume good faith 43: 3998: 3833:Bronchial Asthma 3545:OK, THanks t. - 3519: 3450: 3440: 3432: 3430: 3429: 3417: 3375: 3369: 3363: 3357: 3352: 3350: 3342: 3299: 3288: 3282: 3277: 3275: 3267: 3258: 3194:infected wounds, 3180: 3174: 3169: 3167: 3159: 3136:(9): 1068–1075. 3112: 3110: 3109: 3037: 3027: 3019: 3017: 3016: 3004: 2939: 2929: 2921: 2912: 2849: 2843: 2837: 2831: 2826: 2824: 2816: 2758:for those areas. 2735: 2728: 2646: 2629: 2624: 2390:COVID-19 section 1904: 1903: 1872: 1866: 1860: 1830: 1816:Cochrane Library 1801: 1797: 1794: 1458: 1433: 1432: 1419: 1413: 1406: 1400: 1235: 1233: 1211: 1210: 1204: 1196: 1177: 1171: 1168: 1162: 1161: 1154: 1148: 1145: 1139: 1138: 1131: 1116:health insurance 1056: 912:focus on content 877: 855: 830:focus on content 680: 646: 638: 604: 603: 600: 597: 594: 561: 554: 553: 548: 540: 533: 503: 502: 499: 496: 493: 476: 469: 468: 463: 455: 448: 436: 435: 432: 429: 426: 405: 398: 397: 387: 380: 350: 349: 346: 343: 340: 313: 308: 307: 306: 297: 290: 289: 284: 276: 269: 252: 246: 245: 237: 229: 202: 201: 187: 161: 153: 145: 131: 95:Article policies 16: 4006: 4005: 4001: 4000: 3999: 3997: 3996: 3995: 3936: 3935: 3745:Dry maculopathy 3513: 3433: 3427: 3425: 3381: 3365: 3353: 3343: 3309: 3289: 3278: 3268: 3222: 3170: 3160: 3127: 3107: 3105: 3077: 3020: 3014: 3012: 2968: 2922: 2876: 2839: 2827: 2817: 2784: 2693:, for example. 2662: 2644: 2625: 2608: 2520:review articles 2392: 2359:Herpes zoster: 2241: 2221: 2179:, particularly 2140: 1923:reliable source 1914: 1912:Further sources 1909: 1908: 1907: 1874: 1873: 1869: 1861: 1857: 1826: 1811: 1790: 1788: 1745: 1706: 1530: 1468: 1456: 1417: 1411: 1404: 1402:Fringe theories 1398: 1392: 1369: 1321: 1294: 1270: 1231: 1229: 1221: 1216: 1215: 1214: 1197: 1179: 1178: 1174: 1169: 1165: 1156: 1155: 1151: 1146: 1142: 1133: 1132: 1128: 1112:medical doctors 1107: 1080: 1047: 856: 721: 690: 681: 675: 651: 601: 598: 595: 592: 591: 546: 500: 497: 494: 491: 490: 461: 433: 430: 427: 424: 423: 347: 344: 341: 338: 337: 311:Medicine portal 309: 304: 302: 282: 253:on Knowledge's 250: 231: 230: 225: 121: 116: 115: 114: 91: 61: 12: 11: 5: 4004: 4002: 3994: 3993: 3988: 3983: 3978: 3973: 3968: 3963: 3958: 3953: 3948: 3938: 3937: 3934: 3933: 3932: 3931: 3930: 3929: 3928: 3927: 3926: 3925: 3924: 3923: 3905: 3894: 3893: 3892: 3889: 3869: 3868: 3867: 3866: 3865: 3864: 3863: 3862: 3861: 3860: 3846: 3845:Liver diseases 3843: 3840: 3837: 3834: 3831: 3828: 3825: 3822: 3819: 3816: 3813: 3810: 3807: 3804: 3801: 3799: 3796: 3793: 3790: 3787: 3784: 3782: 3779: 3776: 3773: 3770: 3769:Herpes Simplex 3767: 3764: 3761: 3758: 3755: 3752: 3749: 3746: 3743: 3740: 3737: 3735: 3732: 3730: 3727: 3724: 3721: 3718: 3715: 3712: 3709: 3706: 3703: 3701: 3698: 3695: 3692: 3689: 3686: 3683: 3680: 3677: 3674: 3671: 3668: 3665: 3662: 3659: 3656: 3653: 3650: 3647: 3644: 3641: 3638: 3635: 3632: 3630: 3627: 3624: 3621: 3618: 3615: 3612: 3609: 3606: 3603: 3600: 3597: 3594: 3591: 3589: 3586: 3584: 3581: 3578: 3575: 3572: 3569: 3566: 3562: 3561: 3560: 3502: 3501: 3500: 3499: 3498: 3497: 3496: 3495: 3467: 3466: 3465: 3464: 3463: 3462: 3394:(3): 212–219. 3379: 3377: 3319:(4): 295–317. 3306: 3302: 3300: 3220: 3217: 3214: 3210: 3207: 3205: 3201: 3198: 3195: 3192: 3189: 3186: 3183: 3181: 3125: 3121: 3118: 3115: 3113: 3075: 3071: 3069: 3065: 3063: 3059: 3056: 3054: 3051: 3048: 3046: 3043: 3040: 3038: 2981:(3): 212–219. 2966: 2962: 2959: 2957: 2954: 2951: 2948: 2946: 2942: 2940: 2874: 2870: 2868: 2864: 2861: 2858: 2856: 2852: 2850: 2793:(4): 646–682. 2782: 2778: 2774: 2771: 2760: 2759: 2752: 2746: 2745: 2736: 2726: 2725: 2724: 2723: 2706: 2705: 2683:PubMed Central 2661: 2658: 2657: 2656: 2634: 2615:this hyperlink 2607: 2604: 2603: 2602: 2589: 2586: 2585: 2584: 2577: 2570: 2563: 2556: 2538: 2537: 2536: 2535: 2534: 2489: 2485: 2464: 2463: 2462: 2441: 2391: 2388: 2374: 2373: 2365: 2357: 2356: 2355: 2346: 2345: 2344: 2338: 2332: 2323: 2322: 2321: 2315: 2306: 2300: 2293: 2286: 2285: 2284: 2278: 2269: 2268: 2267: 2261: 2255: 2240: 2237: 2220: 2217: 2216: 2215: 2214: 2213: 2161:47.142.153.211 2139: 2136: 2125:151.20.232.106 2107:151.20.232.106 2092:151.20.232.106 2076:151.20.236.169 2046:151.20.233.113 2042: 2041: 2029:what it says. 2015:151.20.233.113 1993:151.20.233.113 1989: 1988: 1987: 1986: 1985: 1984: 1951:151.20.233.113 1938: 1937: 1913: 1910: 1906: 1905: 1887:(5): 322–345. 1867: 1854: 1853: 1849: 1810: 1807: 1806: 1805: 1783: 1782: 1781: 1780: 1759: 1751: 1744: 1741: 1740: 1739: 1705: 1702: 1701: 1700: 1699: 1698: 1697: 1696: 1695: 1694: 1693: 1692: 1691: 1690: 1689: 1688: 1687: 1686: 1529: 1526: 1512: 1511: 1504: 1503: 1502: 1501: 1484: 1483: 1478: 1471: 1467: 1464: 1463: 1462: 1391: 1388: 1368: 1365: 1363: 1320: 1317: 1293: 1290: 1269: 1266: 1265: 1264: 1220: 1217: 1213: 1212: 1172: 1163: 1149: 1140: 1125: 1124: 1120: 1106: 1103: 1079: 1076: 1058: 1057: 1052:comment added 1036:salicylic acid 1029: 1003: 1002: 1001: 1000: 983: 942: 941: 940: 939: 938: 937: 936: 935: 934: 933: 932: 931: 930: 833: 778: 777: 767:65.129.201.220 739:65.129.201.220 720: 717: 689: 686: 683: 682: 677: 673: 671: 668: 667: 666: 665: 657: 656: 653: 652: 647: 641: 634: 633: 630: 629: 626: 625: 618:Mid-importance 614: 608: 607: 605: 588:the discussion 562: 550: 549: 547:Mid‑importance 541: 529: 528: 525: 524: 517:Low-importance 513: 507: 506: 504: 477: 465: 464: 462:Low‑importance 456: 444: 443: 440: 439: 437: 420:the discussion 406: 394: 393: 388: 376: 375: 372: 371: 364:Low-importance 360: 354: 353: 351: 315: 314: 298: 286: 285: 283:Low‑importance 277: 265: 264: 258: 247: 233: 232: 223: 221: 220: 217: 216: 204: 203: 118: 117: 113: 112: 107: 102: 93: 92: 90: 89: 82: 77: 68: 62: 60: 59: 48: 39: 38: 35: 34: 28: 13: 10: 9: 6: 4: 3: 2: 4003: 3992: 3989: 3987: 3984: 3982: 3979: 3977: 3974: 3972: 3969: 3967: 3964: 3962: 3959: 3957: 3954: 3952: 3949: 3947: 3944: 3943: 3941: 3922: 3918: 3914: 3910: 3906: 3903: 3899: 3895: 3890: 3887: 3886: 3884: 3881: 3880: 3879: 3878: 3877: 3876: 3875: 3874: 3873: 3872: 3871: 3870: 3859: 3855: 3851: 3847: 3844: 3841: 3838: 3835: 3832: 3829: 3826: 3823: 3820: 3817: 3814: 3811: 3808: 3805: 3802: 3800: 3797: 3794: 3791: 3788: 3785: 3783: 3780: 3777: 3775:Herpes Zoster 3774: 3771: 3768: 3765: 3762: 3759: 3756: 3753: 3750: 3747: 3744: 3741: 3738: 3736: 3733: 3731: 3728: 3725: 3722: 3719: 3716: 3713: 3710: 3707: 3704: 3702: 3699: 3696: 3693: 3690: 3687: 3684: 3681: 3678: 3675: 3672: 3669: 3666: 3663: 3660: 3657: 3654: 3651: 3648: 3645: 3642: 3639: 3636: 3633: 3631: 3628: 3625: 3622: 3619: 3616: 3613: 3610: 3607: 3604: 3601: 3598: 3595: 3592: 3590: 3587: 3585: 3582: 3579: 3576: 3573: 3570: 3567: 3563: 3559: 3556: 3555: 3551: 3549: 3544: 3543: 3542: 3538: 3534: 3530: 3526: 3525:Ozone therapy 3522: 3517: 3512: 3511: 3510: 3509: 3508: 3507: 3506: 3505: 3504: 3503: 3494: 3491: 3490: 3486: 3484: 3479: 3475: 3474: 3473: 3472: 3471: 3470: 3469: 3468: 3461: 3457: 3453: 3448: 3444: 3438: 3424: 3421: 3416: 3412: 3408: 3405: 3401: 3397: 3393: 3389: 3385: 3380: 3378: 3376:(Lamberto Re) 3373: 3361: 3348: 3340: 3337: 3333: 3330: 3326: 3322: 3318: 3314: 3307: 3303: 3301: 3297: 3293: 3286: 3273: 3265: 3262: 3257: 3253: 3249: 3246: 3242: 3238: 3234: 3230: 3226: 3221: 3218: 3215: 3211: 3208: 3206: 3202: 3199: 3196: 3193: 3190: 3187: 3184: 3182: 3178: 3165: 3157: 3154: 3150: 3147: 3143: 3139: 3135: 3131: 3126: 3122: 3119: 3116: 3114: 3104: 3101: 3097: 3093: 3089: 3085: 3081: 3076: 3072: 3070: 3066: 3064: 3060: 3057: 3055: 3052: 3049: 3047: 3044: 3041: 3039: 3035: 3031: 3025: 3011: 3008: 3003: 2999: 2995: 2992: 2988: 2984: 2980: 2976: 2972: 2967: 2963: 2960: 2958: 2955: 2952: 2949: 2947: 2943: 2941: 2937: 2933: 2927: 2919: 2916: 2911: 2907: 2903: 2900: 2896: 2892: 2888: 2884: 2880: 2875: 2871: 2869: 2865: 2862: 2859: 2857: 2853: 2851: 2847: 2835: 2822: 2814: 2811: 2807: 2804: 2800: 2796: 2792: 2788: 2783: 2779: 2775: 2772: 2768: 2767: 2766: 2765: 2764: 2763: 2756: 2750: 2744: 2743: 2741: 2737: 2734: 2730: 2729: 2722: 2718: 2714: 2710: 2709: 2708: 2707: 2704: 2700: 2696: 2692: 2688: 2684: 2680: 2679: 2678: 2677: 2673: 2669: 2668:69.94.200.170 2666: 2659: 2655: 2651: 2647: 2643: 2639: 2635: 2633: 2632: 2631: 2628: 2623: 2620:Sincerely, — 2618: 2616: 2611: 2605: 2601: 2598: 2595: 2590: 2587: 2581: 2578: 2574: 2571: 2567: 2564: 2560: 2557: 2553: 2550: 2549: 2547: 2543: 2539: 2533: 2529: 2525: 2521: 2517: 2513: 2509: 2505: 2504: 2503: 2499: 2495: 2490: 2486: 2482: 2481: 2480: 2477: 2474: 2470: 2465: 2461: 2458: 2455: 2451: 2447: 2442: 2438: 2437: 2436: 2432: 2428: 2423: 2422: 2421: 2420: 2417: 2414: 2408: 2404: 2402: 2398: 2389: 2387: 2386: 2383: 2380: 2370: 2366: 2362: 2358: 2353: 2350: 2349: 2347: 2342: 2339: 2336: 2333: 2330: 2327: 2326: 2324: 2319: 2316: 2313: 2310: 2309: 2307: 2305: 2301: 2298: 2294: 2291: 2287: 2282: 2279: 2276: 2273: 2272: 2270: 2265: 2262: 2259: 2256: 2253: 2250: 2249: 2247: 2246: 2245: 2238: 2236: 2235: 2231: 2227: 2218: 2212: 2208: 2204: 2200: 2199: 2198: 2194: 2190: 2186: 2182: 2178: 2174: 2173: 2172: 2170: 2166: 2162: 2158: 2152: 2149: 2146: 2143: 2137: 2135: 2134: 2130: 2126: 2122: 2117: 2116: 2112: 2108: 2102: 2101: 2097: 2093: 2087: 2085: 2081: 2077: 2073: 2067: 2064: 2059: 2056: 2055: 2051: 2047: 2040: 2036: 2032: 2027: 2026: 2025: 2024: 2020: 2016: 2012: 2009: 2003: 2002: 1998: 1994: 1983: 1979: 1975: 1971: 1967: 1963: 1962: 1960: 1956: 1952: 1948: 1942: 1941: 1940: 1939: 1936: 1932: 1928: 1924: 1920: 1919: 1918: 1911: 1901: 1898: 1894: 1890: 1886: 1882: 1878: 1871: 1868: 1864: 1863:Ozone Therapy 1859: 1856: 1852: 1848: 1847: 1843: 1839: 1835: 1831: 1829: 1823: 1821: 1817: 1808: 1804: 1800: 1795: 1793: 1785: 1784: 1778: 1774: 1770: 1766: 1760: 1757: 1756: 1755: 1752: 1750: 1747: 1746: 1742: 1738: 1734: 1730: 1726: 1725: 1724: 1723: 1719: 1715: 1711: 1703: 1685: 1681: 1677: 1673: 1672: 1671: 1667: 1663: 1659: 1658: 1657: 1653: 1649: 1645: 1641: 1640: 1639: 1635: 1631: 1627: 1623: 1619: 1615: 1614: 1613: 1609: 1605: 1601: 1597: 1596: 1595: 1591: 1587: 1583: 1579: 1578: 1577: 1573: 1569: 1565: 1564: 1563: 1559: 1555: 1551: 1547: 1543: 1542: 1541: 1539: 1535: 1527: 1525: 1524: 1521: 1518: 1509: 1508: 1507: 1500: 1496: 1492: 1488: 1487: 1486: 1485: 1482: 1479: 1477: 1474: 1473: 1472: 1465: 1461: 1454: 1453: 1452: 1451: 1445: 1441: 1437: 1430: 1425: 1423: 1416: 1408: 1403: 1395: 1389: 1387: 1386: 1382: 1378: 1374: 1366: 1364: 1361: 1360: 1356: 1352: 1346: 1345: 1341: 1337: 1332: 1329: 1324: 1318: 1316: 1315: 1311: 1307: 1302: 1298: 1291: 1289: 1288: 1284: 1280: 1276: 1267: 1263: 1259: 1255: 1251: 1250: 1249: 1248: 1245: 1243: 1239: 1234: 1226: 1219:Pseudoscience 1218: 1208: 1202: 1194: 1191: 1187: 1183: 1182:Mater Med Pol 1176: 1173: 1167: 1164: 1159: 1153: 1150: 1144: 1141: 1136: 1130: 1127: 1123: 1119: 1117: 1113: 1104: 1102: 1101: 1097: 1093: 1089: 1085: 1078:Moved to talk 1077: 1075: 1074: 1070: 1066: 1063: 1055: 1051: 1045: 1041: 1037: 1033: 1030: 1027: 1023: 1020: 1019: 1018: 1015: 1011: 1007: 999: 995: 991: 987: 984: 982: 978: 974: 970: 966: 962: 958: 957: 956: 952: 948: 943: 929: 925: 921: 917: 913: 909: 908: 907: 903: 899: 894: 893: 892: 888: 884: 880: 879: 876: 872: 868: 864: 860: 852: 851: 850: 846: 842: 838: 834: 831: 827: 826: 825: 821: 817: 812: 808: 807: 806: 802: 798: 794: 793: 792: 791: 787: 783: 776: 772: 768: 764: 760: 756: 752: 751: 750: 748: 744: 740: 736: 730: 726: 718: 716: 715: 711: 707: 703: 699: 695: 687: 670: 669: 664: 661: 660: 659: 658: 655: 654: 650: 645: 640: 639: 623: 619: 613: 610: 609: 606: 589: 585: 581: 580:pseudohistory 577: 576:pseudoscience 573: 569: 568: 563: 560: 556: 555: 551: 545: 542: 539: 535: 522: 518: 512: 509: 508: 505: 488: 484: 483: 478: 475: 471: 470: 466: 460: 457: 454: 450: 438: 421: 417: 413: 412: 407: 404: 400: 399: 395: 392: 389: 386: 382: 369: 365: 359: 356: 355: 352: 335: 334: 329: 325: 321: 320: 312: 301: 299: 296: 292: 291: 287: 281: 278: 275: 271: 266: 262: 256: 248: 244: 239: 238: 219: 218: 215: 212: 210: 206: 205: 200: 196: 193: 190: 186: 182: 179: 176: 173: 172:ScienceDirect 170: 167: 164: 160: 156: 152: 148: 144: 140: 137: 134: 130: 124: 120: 119: 111: 110:Verifiability 108: 106: 103: 101: 98: 97: 96: 87: 83: 81: 78: 76: 72: 69: 67: 64: 63: 57: 53: 52:Learn to edit 49: 46: 41: 40: 37: 36: 32: 26: 25:Ozone therapy 22: 18: 17: 3908: 3897: 3809:Fibromyalgia 3553: 3547: 3516:Roxy the dog 3488: 3482: 3437:cite journal 3426:. Retrieved 3391: 3387: 3347:cite journal 3316: 3312: 3308:“(Cuadrado) 3272:cite journal 3232: 3228: 3164:cite journal 3133: 3129: 3106:. Retrieved 3087: 3083: 3024:cite journal 3013:. Retrieved 2978: 2974: 2926:cite journal 2889:(15): 7890. 2886: 2882: 2821:cite journal 2790: 2786: 2663: 2641: 2619: 2612: 2609: 2524:WhatamIdoing 2511: 2409: 2405: 2393: 2375: 2242: 2222: 2155:— Preceding 2153: 2150: 2147: 2144: 2141: 2118: 2103: 2088: 2070:— Preceding 2060: 2057: 2043: 2004: 1990: 1945:— Preceding 1915: 1884: 1880: 1870: 1858: 1850: 1827: 1824: 1812: 1792:MjolnirPants 1791: 1763:— Preceding 1707: 1628:might help? 1621: 1544:Please read 1531: 1513: 1505: 1469: 1426: 1421: 1409: 1396: 1393: 1370: 1362: 1347: 1333: 1325: 1322: 1295: 1271: 1228: 1222: 1201:cite journal 1185: 1181: 1175: 1166: 1152: 1143: 1129: 1121: 1108: 1081: 1059: 1031: 1021: 1004: 857:— Preceding 779: 754: 733:— Preceding 728: 724: 722: 691: 648: 617: 565: 516: 480: 409: 363: 331: 317: 261:WikiProjects 207: 194: 188: 180: 174: 168: 162: 154: 146: 138: 132: 122: 94: 19:This is the 3781:M.Dupuytren 3090:: 114–121. 2867:inhalation. 2494:CymHastings 2440:explicitly. 2427:CymHastings 1970:WP:WHYMEDRS 1964:Please see 1769:76.14.15.93 1377:Biol. Cons. 1351:Biol. Cons. 1188:(2): 53–6. 1048:—Preceding 990:Hob Gadling 967:because of 961:WP:GOODBIAS 947:50.250.97.5 251:Start-class 31:not a forum 3940:Categories 3913:tgeorgescu 3533:tgeorgescu 3428:2017-12-20 3108:2019-11-24 3015:2017-12-20 2713:tgeorgescu 2695:XOR'easter 2592:disagree. 2569:treatment. 2562:treatment. 2201:Seconded. 1968:and maybe 1851:References 1809:Moved here 1622:repeatedly 1427:Discuss. 1306:ParkSehJik 1279:ParkSehJik 1122:References 973:tgeorgescu 759:PMC9069381 593:Skepticism 584:skepticism 544:Skepticism 487:discussion 3839:Allergies 3407:2045-9912 3248:1422-0067 3149:1029-2470 3103:0891-5849 2994:2045-9912 2902:1422-0067 2753:be given 2512:something 2401:WP:WEASEL 2185:WP:FRINGE 1900:0191-9512 1828:Doc James 1550:WP:FRINGE 1373:talk page 1044:user:ASMB 1026:user:ASMB 969:WP:PARITY 916:consensus 898:Alecsescu 863:Alecsescu 816:Alecsescu 782:Abstrator 88:if needed 71:Be polite 21:talk page 3902:WP:ECREE 3883:WP:MEDRS 3478:WP:MEDRS 3423:29152215 3339:30610225 3264:31426459 3156:22583557 3010:29152215 2918:34360655 2813:19260079 2622:euphonie 2594:Fuzzypeg 2542:WP:MEDRS 2473:Fuzzypeg 2454:Fuzzypeg 2413:Fuzzypeg 2379:Fuzzypeg 2372:pathway. 2203:Delta13C 2183:, & 2181:WP:GEVAL 2157:unsigned 2072:unsigned 2011:24384664 1966:WP:MEDRS 1947:unsigned 1838:contribs 1765:unsigned 1546:WP:MEDRS 1517:Fuzzypeg 1440:contribs 1328:WP:MEDRS 1301:WP:MEDRS 1232:—Entropy 1084:WP:MEDRS 1065:Ktjnwebb 1006:Dischome 965:WP:CITEd 871:contribs 859:unsigned 837:WP:MEDRS 735:unsigned 706:NHSavage 649:Archives 339:Medicine 280:Medicine 209:Archives 178:Springer 143:Cochrane 56:get help 29:This is 27:article. 3415:5674660 3358:value ( 3256:6720777 3204:(Bocci) 3124:(Bocci) 3002:5674660 2910:8346137 2832:value ( 2749:should 2691:MEDLINE 2645:Georgia 2546:Alexbrn 2226:Chemacb 2189:Alexbrn 2177:WP:NPOV 2066:3312702 2031:Alexbrn 1974:Alexbrn 1927:Alexbrn 1714:Alexbrn 1710:WP:FT/N 1662:Alexbrn 1630:Alexbrn 1620:before 1618:WP:PAGs 1586:Alexbrn 1582:WP:PAGs 1554:Alexbrn 1429:davidwr 1193:8935190 1088:WP:SOAP 1050:undated 1040:aspirin 910:Please 828:Please 620:on the 572:science 519:on the 366:on the 3368:|date= 3356:|issn= 3354:Check 3281:|date= 3235:(16). 3173:|date= 3074:Galié) 3068:above) 2855:blood. 2842:|date= 2830:|issn= 2828:Check 2770:(EBM). 2755:alerts 1921:Not a 1704:Fringe 1626:WP:BRD 1466:Safety 1444:e-mail 257:scale. 166:OpenMD 136:PubMed 3898:could 3593:SPINE 3529:WP:AE 2747:They 2642:Sandy 2544:that 2397:WP:OR 2364:pain. 2105:ET.-- 1842:email 1644:WP:OR 1275:ozone 761:DOI: 694:Ozone 192:Wiley 84:Seek 3917:talk 3854:talk 3815:Acne 3548:Roxy 3537:talk 3483:Roxy 3480:? - 3456:talk 3447:link 3443:link 3420:PMID 3404:ISSN 3372:help 3360:help 3336:PMID 3329:ISSN 3296:link 3292:link 3285:help 3261:PMID 3245:ISSN 3177:help 3153:PMID 3146:ISSN 3100:ISSN 3034:link 3030:link 3007:PMID 2991:ISSN 2936:link 2932:link 2915:PMID 2899:ISSN 2846:help 2834:help 2810:PMID 2803:ISSN 2717:talk 2699:talk 2672:talk 2650:Talk 2528:talk 2498:talk 2450:This 2431:talk 2230:talk 2207:talk 2193:talk 2175:See 2165:talk 2129:talk 2111:talk 2096:talk 2080:talk 2050:talk 2035:talk 2019:talk 2008:PMID 1997:talk 1978:talk 1955:talk 1931:talk 1897:ISSN 1834:talk 1773:talk 1733:talk 1718:talk 1680:talk 1666:talk 1652:talk 1634:talk 1608:talk 1590:talk 1572:talk 1558:talk 1548:and 1538:talk 1495:talk 1436:talk 1381:talk 1355:talk 1340:talk 1323:Hi, 1310:talk 1297:This 1283:talk 1258:talk 1207:link 1190:PMID 1096:talk 1092:Ronz 1069:talk 1046:-- 1042:. -- 1010:talk 994:talk 977:talk 951:talk 924:talk 920:Ronz 918:. -- 902:talk 887:talk 883:Ronz 867:talk 845:talk 841:Ronz 820:talk 801:talk 797:Ronz 786:talk 771:talk 743:talk 719:Bias 710:talk 582:and 185:Trip 159:Gale 151:DOAJ 73:and 3919:) 3909:are 3714:A/B 3554:dog 3550:the 3539:) 3489:dog 3485:the 3411:PMC 3396:doi 3321:doi 3252:PMC 3237:doi 3138:doi 3092:doi 3088:124 2998:PMC 2983:doi 2965:al) 2906:PMC 2891:doi 2795:doi 2751:not 2719:) 2652:) 2617:. 2063:PMC 1889:doi 1735:) 1729:Ies 1682:) 1676:Ies 1654:) 1648:Ies 1610:) 1604:Ies 1574:) 1568:Ies 1534:Ies 1457:# ▄ 1442:)/( 1438:)/( 1422:not 1415:POV 1375:.-- 1334:-- 979:) 896:it. 612:Mid 511:Low 358:Low 199:TWL 3942:: 3856:) 3848:C 3531:. 3458:) 3439:}} 3435:{{ 3418:. 3409:. 3402:. 3390:. 3386:. 3364:; 3351:: 3349:}} 3345:{{ 3334:. 3327:. 3317:18 3315:. 3276:: 3274:}} 3270:{{ 3259:. 3250:. 3243:. 3233:20 3231:. 3227:. 3168:: 3166:}} 3162:{{ 3151:. 3144:. 3134:46 3132:. 3098:. 3086:. 3082:. 3026:}} 3022:{{ 3005:. 2996:. 2989:. 2977:. 2973:. 2928:}} 2924:{{ 2913:. 2904:. 2897:. 2887:22 2885:. 2881:. 2838:; 2825:: 2823:}} 2819:{{ 2808:. 2801:. 2791:29 2789:. 2742:: 2701:) 2674:) 2530:) 2500:) 2433:) 2399:, 2232:) 2209:) 2195:) 2187:. 2167:) 2131:) 2113:) 2098:) 2082:) 2052:) 2037:) 2021:) 2013:-- 1999:) 1980:) 1957:) 1933:) 1925:. 1895:. 1885:38 1883:. 1879:. 1844:) 1840:· 1836:· 1775:) 1720:) 1712:. 1668:) 1636:) 1592:) 1560:) 1540:) 1497:) 1418:}} 1412:{{ 1405:}} 1399:{{ 1383:) 1357:) 1342:) 1312:) 1285:) 1260:) 1227:? 1203:}} 1199:{{ 1186:27 1184:. 1098:) 1071:) 1028:-- 1012:) 996:) 953:) 926:) 904:) 889:) 873:) 869:• 847:) 822:) 803:) 788:) 773:) 745:) 712:) 578:, 574:, 54:; 3915:( 3852:( 3842:C 3836:C 3830:C 3824:C 3818:C 3812:C 3806:C 3795:C 3789:C 3778:C 3772:C 3766:A 3760:C 3754:C 3748:C 3742:C 3726:A 3720:B 3708:B 3697:B 3691:B 3685:B 3679:B 3673:B 3667:B 3661:B 3655:B 3649:B 3643:B 3637:B 3626:B 3620:B 3614:A 3608:A 3602:A 3535:( 3518:: 3514:@ 3454:( 3449:) 3431:. 3398:: 3392:7 3374:) 3370:( 3362:) 3341:. 3323:: 3298:) 3287:) 3283:( 3266:. 3239:: 3179:) 3175:( 3158:. 3140:: 3111:. 3094:: 3036:) 3018:. 2985:: 2979:7 2938:) 2920:. 2893:: 2848:) 2844:( 2836:) 2815:. 2797:: 2715:( 2697:( 2670:( 2648:( 2597:★ 2526:( 2496:( 2476:★ 2457:★ 2429:( 2416:★ 2382:★ 2228:( 2205:( 2191:( 2163:( 2127:( 2109:( 2094:( 2078:( 2048:( 2033:( 2017:( 1995:( 1976:( 1953:( 1929:( 1902:. 1891:: 1832:( 1771:( 1731:( 1716:( 1678:( 1664:( 1650:( 1632:( 1606:( 1588:( 1570:( 1556:( 1536:( 1520:★ 1493:( 1446:) 1434:( 1431:/ 1379:( 1353:( 1338:( 1308:( 1281:( 1256:( 1244:) 1242:C 1240:/ 1238:T 1236:( 1209:) 1195:. 1137:. 1094:( 1067:( 1008:( 992:( 975:( 949:( 922:( 900:( 885:( 865:( 843:( 818:( 799:( 784:( 769:( 741:( 708:( 624:. 523:. 489:. 370:. 336:. 263:: 214:1 211:: 195:· 189:· 181:· 175:· 169:· 163:· 155:· 147:· 139:· 133:· 58:.

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

Index