Talk:Wound healing

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which circulating proenzymes are converted in sequence to activated proteases. The traditional concept of the clotting system evolved from test tube analysis and follows two pathways: the intrinsic pathway involves components normally present in blood, and the extrinsic pathway is initiated by the tissue lipoprotein. The clotting system and inflammation are intimately connected processes. Injury causes hemorrhage from damaged vessels and lymphatics. Vasoconstriction occurs almost immediately as a result of release of catecholamines. Various other vasoactive compounds, such as bradykinin, serotonin and histamine are released from tissue mast cells. They initiate the process of diapedesis, a passage of intravascular cells through vessel walls and into the extravascular space of the wound. Platelets derived from the hemorrhage form a haemostatic clot. The platelets release clotting factors to produce fibrin, which is haemostatic and which forms a mesh for the further migration of inflammatory cells and fibroblasts. Fibrin is produced from fibrinogen, which is formed by the action of thrombin in the presence of thromboplastin. If the fibrin mesh is eliminated, the wounds ultimate strength is diminished. Fibrin serves as the frame work on which fibroblasts and endothelial cells to develop along. Platelets are also extremely important because they are the first cells to produce several essential cytokines, which modulate most of the subsequent wound healing events. These cytokines include PDGF, EGF, TGF-β.

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cells as well as activated endothelium. These inflammatory cells also elaborate TGF-β, PDGF, and bFGF and therefore promote fibroblast migration and proliferation. If the appropriate chemotactic stimuli are present, mast cells, eosinophils, and lymphocytes may be increased in number. Each of these can contribute directly or indirectly to fibroblast migration and proliferation. Of the growth factors involved in inflammatory fibrosis, TGF-β appears to be the most important because of the multitude of effects that favor fibrous tissue deposition. As repair progresses, the number of proliferating endothelial and fibroblast cells decreases. Fibroblasts progressively become more synthetic and deposit increased amounts of ECM. Fibrillar collagens (collagens I, II, III) form a major portion of the connective tissue in repair sites and are important for the development of strength in healing wounds. Collagen synthesis by fibroblasts develops as early as days 3 to 5 and continues for several weeks depending on the size of the wound. Ultimately, the granulation tissue scaffolding is converted into a scar composed of spindle-shaped fibroblasts, dense collagen, fragments of elastic tissue and other ECM components. As the scar matures, vascular regression continues, eventually transforming the richly vascularized granulation tissue into a pale, avascular scar.

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abdominal wound can be generated by vomiting, coughing or ileus. Wounds can ulcerate because of inadequate vascularization during healing. For example, lower extremity wounds in individuals with atherosclerotic, peripheral vascular disease typically ulcerate. Non healing wounds also form in areas devoid of sensation, neuropathic ulcers, as seen in diabetic peripheral neuropathy. Excessive formation of the components of the repair process can also complicate wound healing. Aberrations of growth may occur even in what may begin initially as normal wound healing. The accumulation of excessive amounts of collagen may give rise to a raised tumorous scar, either a keloid or hypertrophic scar. Keloid scars are more common in blacks. Exuberant granulation tissue may interfere with epithelialization and should be removed. Contraction in the size of a wound is an important part of the normal healing process. An exaggeration of this process is called a contracture and results in deformities of the wound and the surrounding tissues. Contractures are particularly prone to develop on the palms, soles and the anterior aspect of the thorax. These are commonly seen after serious burns and may compromise joint movement.

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be feasible to turn Knowledge (whose coverage extends to everything in the universe) into something that teaches everyone in the world everything there is to know in a way that seems effortless to the learners. People may need to have enough study skills (patience, motivation, attention) to open those links in a new tab (or hover over them and get a popup/tooltip) and skim it a little before coming back to the main article and continuing. While knowing that they have not mastered anything—just gotten enough gist to continue learning. At least further than 2 degrees of separation before giving up. Part of it is reasonable expectations—you can't expect Knowledge to explain a wide and deep swath of scientific reality to you in 20 minutes that university classes take 1 or 2 years to teach to a premed student. And yet that's how far afield you can go by casually clicking around from one Knowledge article to the next. It's kind of like how you can't expect to read a 200-page college textbook in one day, despite that you can easily flip through it that quickly. Even if you flip through the pages and skim over all the words, you can't

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keeps the information very neutral. States a lot of facts and information. Sources are reliable and back up what the article is saying. The sources are up to date. The sources also give a lot of good and reliable information. The organization is okay. I think it could use some work. I feel like a lot of information is just thrown on a page and it's hard to find things. Spelling looked good and I did not find any errors. The images are great. It helps you understand the information you are reading. It shows the different kinds of wounds and the stages a wound goes through to heal. The conversations going on were talking about specific things going on in the article. Whether it was something the reader didn't like or how the liked a specific thing or wanted clarification on a specific something. It is part of a wiki project. It is part of the physiology project. I really like this article. It has really good information and pictures. It gives a lot of information and goes into specifics about everything. I think the information could be a little bit more organized. I think it is well-developed.

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the microvasculature that permit the plasma proteins and leukocytes to leave the circulation and iii) emigration of the leukocytes from the microcirculation and their accumulation in the focus of injury. Inflammation is a vascular and cellular response that serves to clean dead tissue and foreign bodies from the wound. During this phase, the microcirculatory response is promoted with aggregation of blood cells, kinins, and products favouring haemostasis, and isolation and neutralization of tissue irritants. With this, cleaning of the damaged tissue allows tissue repair. This phase lasts from three to ten days. Macrophages move into the inflammatory environment and are important constituents of granulation tissue, responsible for clearing extracellular debris, fibrin, and other foreign material at the site of repair.

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matrix metalloproteinases, which are dependent on zinc ions for their activity. Metalloproteinases consist of interstitial collagenases(cleave the fibrillar collagen), gelatinases(cleaves type IV collagen), stromelysins (acts on a variety of ECM proteins including proteoglycans, fibronectin, laminin and amorphous collagens) and membrane bound matrix metalloproteinases. Matrix metalloproteinases are inhibited by a family of specific tissue inhibitors of metalloproteinases which are produced by most mesenchymal cells. Different tissues will have varying modifications to their remodeling process, e.g. bone will have deposition of calcium hydroxyapatite.

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subsequent cell migration. This is followed by migration of endothelial cells toward the angiogenic stimulus, vascular endothelial growth factor (VEGF) and fibroblast growth factors (bFGF). There is proliferation of endothelial cells behind the leading front of migrating cells. Maturation of endothelial cells then occurs which includes inhibition of growth and remodeling into capillary tubes which is controlled by the angiopoietins and their receptors. Recruitment of periendothelial cells to provide support for the endothelial tubes is the final step in maturation.

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not take much to shut down capillary flow, consequently people who can not move will see tissue destruction. The impact of fat on the flow of blood through capillaries and the impacts on the endothelial cell response will affect microthrombi, hence perfusion, hence repair. At blood sugar levels much above 126, the repair process is adversely affected, the level of reduced glutathione GSH)is low in diabetics and this impacts endothelial cell behaviour. You can go to Google scholar or PubMed and read on these things.----------McGowan

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under the clot and any attempt to pull off the clot months after the injury, results in new injury. These normal and abnormal processes are not adequately described in this article. Perhaps there are healing substances under the clot that cause new skin to grow, but if these substances are not all present, no new skin forms or new dermal cells form, but fail to complete an epidermis.

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ii) Metabolic status can change wound healing. As exemplified by diabetes mellitus which can slow wound healing. iii) Circulatory status as inadequate blood supply and impaired venous drainage impair wound healing iv) Hormones such as glucocorticoids have anti-inflammatory effects that influence various components of inflammation and fibroplasia and also inhibit collagen synthesis

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and cutting parts you think are unnecessary from proliferation. Also, if you want to take the time to turn all the text's references into footnote links so the text is smaller and easier to read, that would be great. And if you want to find links for all of the references and eliminate ones you think are unnecessary, also great. Matterafact, do whatever you want to it. --

214: 390: 363: 400: 1505:, and have said so in several other WP science/ technology/ medicine Talk Page discussions. A heavy emphasis on jargon is a common WP weakness in these kinds of articles. I would like to see an accessible version of each topic at the beginning of such articles. Then, if a reader would like to delve deeper, the more complex information would follow. 1919:

It starts off by stating exactly what wound healing is so it catches the audiences attention right away. It states what the article is going to be about and gets right to the point. Content is up to date. Article does a very good job of explaining all the different stages. The article is unbiased and

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After a clot has formed and inflamation decreases, there is growth of new skin under the clot. After new skin has formed, the fibers that hold the clot to the wound break or weaken so that the clot falls off or can be easily pulled off without damaging the new skin. Sometimes new skin does not form

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I noticed that the section on Scarless wound healing explains the difference between Scarless and Scar Free but then seems to confuse the two in the statement later in the section that reads, "Scarless wound healing only occurs in mammalian foetal tissues and complete regeneration is limited to lower

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Acute Inflammatory Process: Acute inflammation is the immediate and early response to an injurious agent. It is complex reaction the vascularized connective tissue. There are three major components: i) alterations in vascular caliber that lead to an increase in blood flow, ii) structural changes in

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Coagulation: Coagulation is the process by which prothrombin is converted into the proteolytic enzyme thrombin, which in turn cleaves the fibrinogen molecule to form insoluble fibrin in order to stabilize and add to the platelet plug. Coagulation consists of a series of zymogen activation stages in

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Impressive discussion. When I worked on the early topical hyperbaric driven tissue regeneration program with Sandia Nat Lab/UCLA/VA, it was noticed that scar tissues did not form. We were able to fill deep ulcers with healthy tissue in just a few weeks. The only other example of this was working with

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I don't know how hard you looked before you felt it necessary to declare the page bullshit, but primary intention is where the skin heals with the margins of the wound in apposition. No new area of tissue is required to close the defect. Secondary intention usually occurs with more extensive wounds,

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From a lay-mans point of view, I would think that a wound (scab) left to dry would be natural and add that protective barrier to the environment. Washing the area is good and with this it does help create openings for secretion of blood and pus during times of inflammation and infection. I have this

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Migration of fibroblasts to the site of injury and their subsequent proliferation are triggered by multiple growth factors, including TGF-β, PDGF, EGF, FGF, and the so called fibrogenic cytokines, interleukin-1 and TNF-α. These growth factors are derived from platelets and a variety of inflammatory

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Re: nutrition and common problems---------smoking, high blood sugar, and high fat diets all impact the healing process. If you are concerned about pressure ulcers, then how the capillary pressures are affected and hence blood flow will play out in the progression or recession of the problem. It does

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A great deal of material was blanked in may and I didn't notice till now. I'm in the process of restoring it and many of the refs that were removed. I'm also making some changes, and this may take a couple hours. I'd appreciate it if, as a favor to me, you could wait to make any edits until after

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t of each section or something, that would be cool. Though I'd say this page still needs little blurbs about each phase and links to the pages in that case. Also, the proliferation phase is too long in this page and the maturation phase is too short. You can help by expanding the maturation phase

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pair, or neither of those is related to this; the pigeonholed thinking often has poor grasp of that. User:Preslethe's point is a good one (the ninth-grade textbook had much sounder pedagogical design than many WP articles do; WP has something to learn from the textbook's design), and yet it may not

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Definitions are another weak point. Terms are added into article as in-site links to their own article. Fine, but as the confused casual reader clicks those links, they are instantly confronted by another set of jargon for which they have to click links in order to try to figure out what the second

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Wound healing is a complex but orderly phenomenon involving a number of processes: i) coagulation ii) induction of an acute inflammatory process by the initial injury iii) regeneration of parenchymal cells iv) migration and proliferation of both parenchymal and connective tissue cells v) synthesis

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Wound strength: For skin, when sutures are removed, usually at the end of the first week, wound strength is approximately 10% of the strength of unwounded skin, but it increases rapidly over the next 4 weeks. At three months, the tensile strength of the wound is about 70 to 80% of unwounded skin.

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I'm trying to change the Harvard refs to footnote style to make it shorter and more readable, but I can't get the numbers to correspond to the numbers in the footnotes; they just go up in order they're put in the article, even if the same thing is cited twice. Anyone know how to fix this? If you

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I was reading this article today and I agree. I've re-written the first two paragraphs to aim for a more general audience. I've tried to stay as accurate as possible, but leaving needless details or jargon. I started with the introductory paragraphs because that's what most people see first. Feel

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Many years ago, my ninth-grade science textbook had a great little section on the healing of wounds—at least wounds to human skin, especially abrasions and lacerations. (Let's not forget that there are other kinds of wounds whose healing should be considered, such as bone fractures and wounds to

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People who know me would say I'm no intellectual lightweight. But I'm also no doctor, and have no deep, intimate acquaintance with the science of wound-healing; and the latter fact means that it's only as a layman that I call this article "quite good", and so I readily admit that that evaluation

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site. (Some search results will link to full, free articles while most provide an abstract summary only. If you want to see a whole, though protected, article, contact the research librarian at your public library who may be able to order it for you, or contact the medical librarian at your local

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of WP ledes are often lacking in ways that can be improved when an editor comes along who is willing to think critically about them. Often on Knowledge the concept of "X is a type of Y that has attribute Z"—a concept essential to understanding and stating "what something is"—is missing from lede

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I was recently released from prison. While there, I became fascinated by the whole process of tissue repair through a brief mention in James Gills' "Darwin under the Microscope." I'm by no means ANY kind of an expert on the subject, but yours is the first I've read so specifically tuned to the

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Pathological aspects of wound healing: Inadequate formation of granulation tissue or assembly of a scar can lead to wound dehiscence or ulceration. Dehiscence or rupture of a wound is most common after abdominal surgery and is due to increased abdominal pressure. This mechanical stress on the

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Tissue remodeling: The replacement of granulation tissue with a scar involves transitions in the composition of the ECM. This change in ECM composition is brought about by changing balances of synthesis and degradation. Degradation of collagen and other ECM proteins is achieved by a family of

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I added a little on scarring, and was going to add two recent reviews, but for some reason it won't work, can someone post to the tutorial on adding references, I can't seem to get the right combination of links. The reference are Eur J Surg. 2002;168(10):523-34. and Wound Repair Regen. 2005

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According to a British pharmacy company, skin wounds heal more effectively if they are not allowed to dry out and form a hard scab. Is this true, and if it is, what studies have shown evidence for it? Can someone add a section on it to the article, and also anything about the effectiveness of

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Local factors which influence healing include the following: i) Infection is the single most important cause of delay in healing ii) Mechanical factors such as early motion of wounds also delay healing iii) Foreign bodies such as sutures and debris constitutes impediments to healing iv) Size,

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Formation of fibrous tissue occurs by formation of granulation tissue which consists of new small blood vessels and proliferation of fibroblasts. Formation of new blood vessels first involves degradation of the basement membrane of parent vessels, to allow formation of a capillary sprout and

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Regeneration of parenchymal cells: Regeneration denotes replacement of injured cells by cells of the same type, sometimes leaving no residual trace of the previous injury. With injury, cell replication is stimulated which is controlled by a complex interplay of growth factors, growth factor

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I agree - I think the article is a great start, but could use some additions and improvements. In particular, I think a section about "common problems encountered during the wound healing process" would be very relevant. At the same time, I think many of the terms in use would be much more

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Local and systemic factors that influence wound healing: Systemic factors which influence wound healing include: i) Nutrition has profound effects on wound healing. Protein deficiency, for example, and particularly vitamin C deficiency inhibit collagen synthesis and retard wound healing.

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Fibrosis: Tissue destruction of both parenchymal and stromal tissue cannot be repaired solely by regeneration. Repairing tissue damage then occurs by replacement of nonregenerated parenchymal cells by connective tissue. This involves: i) formation of new blood vessels ii) migration and

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Overall quite good, however I think the section on proliferation could use some work on flow --the tie between collagen/angiogenesis/epithelialization and granular tissue was a bit confusing. I'm by no means an expert on this and I don't feel comfortable making the changes myself.

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Thanks for this straight forward explanation of what is often seen as an overwhelming process. I know what you mean about writing too much. I had to cut out most of process in the report I'm writing. But such is the work of editing, right? Thanks again. this is just fantastic.

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evaluation might be way off the mark. Why? Scabs are an example. This is an article about wound-healing. Near the top is a series of photos showing a scab. But how many times does the word "scab" appear in the article? Five (excluding one photo caption)—in an article of

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nickle size wound on my leg I been watching for two weeks now and seems to be coming along well. Very low fluid draining. I think to "pick" the scab and or moisten it, you run the risk of it releasing prematurely in turn not getting the proper tissue replaced or repaired.

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that indicates the extent to which many people (including those who wrote that lede to date) tend to think in a pigeonholed sort of way—separate little boxes with poor understanding of how anything truly relates to anything else. Understanding whether two terms are

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level terms mean. On and on, until the reader gives up in frustration. By no means do I thinks that terms shouldn't be linked, but adding a simple definition would go a long way towards making articles more comprehensible. Example of the ping-ponging game around WP:

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words about the healing of a wound before ever uttering such a common word as "scab"? When "scab" finally appears, it's not even defined. Pity the poor reader who wants to know the basics of a scab, such as what it's made of, the roles it plays, and how (in a

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I don't have the time to research the topics in this article to add a good initial section for the layman; but I am adding my voice to the other pleas at this page for something that's easily accessible to the knowledge, interests, and intelligence of the

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As a general reader coming here for information, I was disappointed there was no information regarding nutrition to support wound healing. Maybe a section would be helpful on what nutrients are essential for wound healing? Like protein, etc.

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I don't mind the process of coining new words for new things, I grimace when I read "terms of art" that remind me of the slang of the criminal underground, but this is ridiculous! At least invent a Latin or Greek word I can look up.

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Great article, I have made some minor changes to the introduction and will look at the rest when I can. If you don't like them - just delete! Thanks. (I spend all day 9-5 looking at wounds so might have something useful to say).

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Agreed. I followed a disambig page here for Scab and was looking for a 10,000 foot view of what they're made out of, how they form, and why they happen. This article is very jargon-heavy, even in the introductory paragraph.

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This article should cross-reference WP articles on Wound dressing and wound care, development and current status of moist bandaging technique as facilitating and speeding healing process while protecting from infection.

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Ooh, that's an awesome idea. We could maybe even make an image, that would be very cool. I'll add this to my embarrassingly vast to do list, but if others want to get to this before the end of the next century...

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For the time lapse series of pictures titled “Deep wound on shin with stitches healing over five weeks” in this article, one of the pictures is a landscape that has nothing to do with the subject matter.

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had a wound and watched it heal?) without having to click on, or hover over, what feels like an average of at least two words every paragraph just to get a vague idea of what the thing being mentioned

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to explore related topics further of their own accord. Don't make hop-scotching all over Knowledge a condition of spontaneously deciding to look up a specific topic. Try something like this:

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receptors, transduction mechanisms and transcription factors. The entry and progression of cells through the cell cycle are controlled by changes in the levels and activities of cyclins.

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hospital.) For example, this particular study (abstract only) found that humble over-the-counter supplies increase the healing effectiveness in wounds that even we amateurs can utilize:

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You have nothing to apologise for. I think this is excellent, interesting and very well supported. Things that might improve it would be internal Knowledge links and illustrations. --

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Sounds like a great idea, I can work on getting rid of the too technical language. If you notice something in particular, definitely bring it up here, or have a go at it yourself!

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could be way off the mark (i.e., a doctor who deals extensively with wound-healing might be able to detect that this article is a poor description of that science; I don't know).

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understandable in ENGLISH instead of Greek and/or Latin. To cite one example I changed, I don't see the sense in using words like "erythematous" when simply "red" is meant. --

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Sorry I made this page so rediculously long; it's most of the contents of a paper I wrote for a wound healing tutorial for school. If you want to make new pages ou

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At the same time, it is as a layman that I suggest that this article is quite inadequate for a general-interest encyclopedia, and I feel no need to suggest that

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location and type of wound also influence wound healing. Wounds to the face and other well vascularized areas heal more quickly than poorly vascularized wounds

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I'm about half done converting the refs and have removed the in use template. I'll have to put it up again when I finish replacing the refs. Thanks everyone!

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I think scabs need their own article, this is one of the densest most complex articles I have seen outside of mathematical topics and that's saying something.

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I was looking here for information on scabs and I agree with the comment above that at least scabs should be defined on first appearance in text, please.

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And speaking of defining things: I love fancy vocabulary—but I also love being able to read an article about such a common topic (really, who

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of ECM proteins vi) remodeling of connective tissue and parenchymal components vii) collagenization and acquisition of wound strength

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embryonic tissues. You may thus want to go back and review some of the work of Madalene Heng to get this mechanism. Dr. E. McGowan

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I remove the notice. If that's not possible, let me know and I can add your edits into the version I'm working on. Thanks much,

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proliferation of fibroblasts iii) deposition of extracellular matrix (ECM) iv) maturation and organization of the fibrous tissue

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it that fast. If you could, four-year degrees could be had in four weeks. Oh well, a complex topic ... food for thought ...

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I've stuck the tag back up so I can finish the other half of converting the refs. Let me know if anything comes up.

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Why are there links to sites about maggots when this not discussed in the text? The final link is also inaccesiblem

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Insert non-formatted text here You know maybe it is always a good idea when it is long it will give good answer's.

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Jan-Feb;13(1):7-12. I plan to extend the scarring section slightly and improve the links to pathological scarring

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article should do: start with the basics, and then proceed to higher and higher levels of scientific detail.

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It appears that a (nonetheless, interesting) landscape photo has been inserted into this group of images.

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It would be great if you guys could add a 'wound healing for dummies' section for the non-medical folks.

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vertebrates, such as salamanders, and invertebrates." I think the correct term there is Scar free.

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free to comment on my approach; I will try to clean up more of this article when I have the time.

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Does this link really provide more info? "BioTherapeutics Education and Research Foundation." --

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on Knowledge. If you would like to participate, please visit the project page, where you can join

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A lot of this article was removed at the end of May 2006. I'm wondering why it was all removed.

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or ones which are not sutured closed and tend to gape open. An area of new scar tissue forms.

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Vandalism of image captioned "Deep wound on shin with stitches healing over five weeks"?

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is a diff-link to that discussion to enable quick access to it once it is archived.

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everything parenthetically. At some point it's a degradation of clarity to change "

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Influence of Short-term, Repeated Fasting on the Skin Wound Healing of Female Mice

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This article should cross-reference WP articles on Wound dressing and wound care.

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mechanics of the process. Just want to thank you for feeding a hungry mind!

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plug formation, platelets stick together to form a temporary seal. . ." -

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please add a timeline. ex. number of days until this phase... etc etc.

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And, also, shouldn't "scar free" be hyphenated, namely "scar-free"?

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of angiogenesis (formation of new blood vessels)? No. It doesn't.

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That's a fair point, although there is also a reasonable limit to

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other words. Is it realistic that a layman would talk for nearly

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Knowledge level-5 vital articles in Biology and health sciences

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Wikipedia_talk:WikiProject_Medicine#Scarless wound healing

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Knowledge vital articles in Biology and health sciences

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openers; instead, one finds a lack of interlinking and

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B-Class vital articles in Biology and health sciences

515: 1691:(another kind of protein)." But it is true that the 288:, a collaborative effort to improve the coverage of 643: 1464:non-animal tissue.) It started with a brief and 1239:hydrocolloid plasters making wounds heal better? 33:for general discussion of the article's subject. 932:Less technical section for non-medical readers? 421:and that biomedical information in any article 674:do, let me know or do it yourself. Thanks. -- 644:{\displaystyle  1597:the casual reader to understand the text and 1428:words. The first use of "scab" occurs after 419:Manual of Style for medicine-related articles 197: 157: 8: 2004:Physiology articles about an unassessed area 1286:http://www.ncbi.nlm.nih.gov/pubmed/25059458 1007:will help get your message acted upon. — 357: 250: 1573:"Why was I here, again? Screw Knowledge!" 826:Suggested refinement: proliferation phase 514: 1942:2603:8001:6E00:B2B5:F55F:3852:CBD5:9A0E 1856:Sorry - I posted too soon. That's me - 1408:Simultaneously quite good and terrible? 359: 252: 211: 1736:yes, please clarify formation of scabs 1625:the body processes that stop bleeding 1311:Apparent consensus for this merge on 183: 7: 2029:High-importance dermatology articles 1679:(the stopping of bleeding) involves 411:This article is within the scope of 282:This article is within the scope of 428:Knowledge talk:WikiProject Medicine 241:It is of interest to the following 23:for discussing improvements to the 1999:Mid-importance Physiology articles 1796:Besides the article is mostly BS. 14: 2019:Mid-importance medicine articles 1969:Knowledge level-5 vital articles 1005:my new section on this talk page 790:OK, changes done, tag removed. 423:use high-quality medical sources 398: 388: 361: 302:Knowledge:WikiProject Physiology 275: 254: 221: 212: 45:Click here to start a new topic. 2034:Dermatology task force articles 2009:WikiProject Physiology articles 718:great work! so interesting... 651:=='''Headlinetext'''==}" /: --> 457:This article has been rated as 322:This article has been rated as 305:Template:WikiProject Physiology 2039:All WikiProject Medicine pages 1979:B-Class level-5 vital articles 1468:understandable description of 437:Knowledge:WikiProject Medicine 1: 1930:05:20, 21 February 2023 (UTC) 1667:and clotting factors such as 1501:I thoroughly agree with you, 926:10:47, 12 February 2008 (UTC) 906:01:27, 11 February 2008 (UTC) 886:23:13, 28 November 2007 (UTC) 836:23:01, 19 February 2007 (UTC) 801:05:19, 31 December 2006 (UTC) 786:04:07, 31 December 2006 (UTC) 771:06:34, 27 December 2006 (UTC) 755:04:00, 27 December 2006 (UTC) 512:=='''Headlinetext'''==}": --> 479:This article is supported by 440:Template:WikiProject Medicine 296:and see a list of open tasks. 42:Put new text under old text. 2024:B-Class dermatology articles 1891:17:01, 7 November 2019 (UTC) 1866:22:30, 2 December 2014 (UTC) 1852:22:26, 2 December 2014 (UTC) 1728:03:25, 4 December 2014 (UTC) 1647:07:44, 3 December 2014 (UTC) 1403:21:55, 25 January 2014 (UTC) 1382:18:00, 8 February 2021 (UTC) 1298:08:13, 3 December 2014 (UTC) 961:delldot on a public computer 821:23:26, 25 January 2007 (UTC) 734:12:02, 10 October 2006 (UTC) 679:14:50, 20 October 2005 (UTC) 669:06:33, 20 October 2005 (UTC) 659:01:17, 18 October 2005 (UTC) 1994:B-Class Physiology articles 1874:Fasting & wound healing 1352:11:44, 4 October 2013 (UTC) 1333:11:15, 4 October 2013 (UTC) 1042:17:36, 25 August 2008 (UTC) 346:has not yet been associated 50:New to Knowledge? Welcome! 2055: 1830:02:14, 12 March 2014 (UTC) 1806:00:51, 12 March 2014 (UTC) 1783:06:30, 11 April 2015 (UTC) 1752:17:05, 20 April 2014 (UTC) 1441:description) it's formed. 1270:01:24, 19 March 2013 (UTC) 1249:10:23, 30 April 2012 (UTC) 1100:No, so I have removed it. 1076:10:10, 9 August 2009 (UTC) 1058:15:31, 18 April 2009 (UTC) 1003:You aren't alone. I hope 952:18:49, 25 April 2008 (UTC) 856:09:44, 9 August 2009 (UTC) 703:17:07, 23 March 2010 (UTC) 482:the Dermatology task force 463:project's importance scale 2014:B-Class medicine articles 1838:Somewhere along the way, 1788:Wth is Primary intention? 1767:16:25, 17 June 2023 (UTC) 1687:(a serine protease ) and 1637:Thank you for your time, 1586:Knowledge in frustration. 1496:16:26, 3 March 2014 (UTC) 1195:19:09, 9 March 2010 (UTC) 1110:20:08, 27 July 2009 (UTC) 1095:13:44, 27 July 2009 (UTC) 1017:16:29, 3 March 2014 (UTC) 478: 456: 383: 343: 321: 270: 249: 80:Be welcoming to newcomers 1950:02:11, 30 May 2023 (UTC) 1910:06:02, 11 May 2022 (UTC) 1227:15:03, 15 May 2011 (UTC) 1027:Section Addition Idea(s) 991:16:10, 2 June 2013 (UTC) 1548:: "In the second step, 1388:New skin under the clot 972:06:49, 8 May 2008 (UTC) 645:=='''Headlinetext'''==} 348:with a particular area. 1964:B-Class vital articles 1599:to stay in the article 1554:"What's a platelet???" 1531:"What's hemostasis???" 1306:Scarless wound healing 739:Major edit in progress 646: 475: 340: 285:WikiProject Physiology 75:avoid personal attacks 647: 474: 339: 228:level-5 vital article 123:Find medical sources: 100:Neutral point of view 513: 414:WikiProject Medicine 105:No original research 1234:Moist wound healing 841:Note on scar tissue 308:Physiology articles 1484:Knowledge reader. 641: 476: 341: 237:content assessment 129: 86:dispute resolution 47: 1368:comment added by 1260:comment added by 1230: 1213:comment added by 1185:comment added by 970: 954: 942:comment added by 924: 888: 872:comment added by 799: 784: 769: 753: 693:comment added by 501: 500: 497: 496: 493: 492: 443:medicine articles 356: 355: 352: 351: 206: 205: 128:Source guidelines 127: 66:Assume good faith 43: 2046: 1826: 1818: 1711:hyponym/hypernym 1384: 1329: 1321: 1272: 1229: 1207: 1197: 1061: 968: 964: 962: 937: 922: 918: 916: 867: 795: 780: 765: 749: 705: 652: 649: 648: 642: 637: 596: 445: 444: 441: 438: 435: 408: 403: 402: 401: 392: 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