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due to its similarity to these viruses. Canine minute virus was originally discovered in
Germany in 1967 in military dogs, although it was originally thought to not cause disease. Dogs and puppies are infected orally, and the virus is spread transplacentally to the fetuses. Symptoms are seen most
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The genome is 5.4 kilobases in length. The termini are palindromic. There is a single P6 promoter which through the mechanism of alternative splicing and alternative polyadenylation two nonstructural proteins (NS1 and NP1) and two capsid proteins (VP1 and VP2) are transcribed. The NS1 protein is
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indispensable for genome replication. The NP1 protein, unique to the
Bocaparvovirus genus, appears to be critical for optimal viral replication, as the NP1 knockout mutant of MVC suffers from severe impairment of replication.
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is infected between 25 and 30 days of gestation and can result in abortion. When the dam is infected between 30 and 35 days, the puppies were sometimes born with
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446:"Canine parvovirus type-1 (MVC): Pathomorphological studies on the experimentally infected fetus and MVC-infected cultured cells"
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34:
319:"The canine minute virus (minute virus of canines) is a distinct parvovirus that is most similar to bovine parvovirus"
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416:"Neonatal Viral Infections of Pups: Canine Herpesvirus and Minute Virus of Canines (Canine Parvovirus-1)"
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In experimental infections, the virus is spread transplacentally when the
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commonly between the ages of one to three weeks and include severe
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Canine
Infectious Diseases: From Clinics to Molecular Pathogenesis
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lesions in fetuses in experimental infections were found in the
220:. A virus causing respiratory disease in humans has been called
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360:"Human bocavirus: developing evidence for pathogenicity"
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Schwartz D, Green B, Carmichael L, Parrish C (2002).
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International
Committee on Taxonomy of Viruses (ICTV)
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420:Recent Advances in Canine Infectious Diseases
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235:. In severe cases, illness can be fatal.
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231:, difficulty breathing, and
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515:Carnivore bocaparvovirus 1
485:Carnivore bocaparvovirus 1
291:Carnivore bocaparvovirus 1
173:Carnivore bocaparvovirus 1
146:Carnivore bocaparvovirus 1
23:Carnivore bocaparvovirus 1
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28:
21:
289:"ICTV Taxonomy history:
414:Carmichael, L. (2004).
184:minute virus of canines
336:10.1006/viro.2002.1674
619:Animal viral diseases
444:Hashimoto A (1999).
30:Virus classification
554:Canine minute virus
358:McIntosh K (2006).
206:. It is similar to
179:Canine minute virus
163:Canine minute virus
190:) is a species of
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477:Taxon identifiers
209:bovine parvovirus
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452:. Archived from
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16:Species of virus
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260:small intestine
223:human bocavirus
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97:Quintoviricetes
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377:10.1086/508228
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216:structure and
196:of the family
193:Bocaparvovirus
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133:Bocaparvovirus
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456:on 2005-03-09
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370:(9): 1197–9.
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629:Parvovirinae
624:Dog diseases
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458:. Retrieved
454:the original
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428:. Retrieved
424:the original
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364:J Infect Dis
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300:. Retrieved
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252:Pathological
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199:Parvoviridae
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121:Parvoviridae
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109:Piccovirales
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73:Shotokuvirae
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61:Monodnaviria
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43:(unranked):
22:
509:Wikispecies
244:myocarditis
176:, formerly
613:Categories
460:2007-04-07
430:2006-06-25
275:References
500:Q18907848
302:9 January
140:Species:
68:Kingdom:
583:11459353
569:Q5032416
563:Wikidata
494:Wikidata
396:17041844
345:12441065
323:Virology
266:Virology
248:anasarca
233:anorexia
229:diarrhea
155:Synonyms
116:Family:
80:Phylum:
542:1511866
387:7109811
214:protein
212:in its
128:Genus:
104:Order:
92:Class:
596:329639
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578:IRMNG
529:69BWR
54:Realm
47:Virus
591:NCBI
537:NCBI
392:PMID
341:PMID
304:2019
258:and
256:lung
246:and
204:dogs
182:(or
524:CoL
382:PMC
372:doi
368:194
331:doi
327:302
240:dam
218:DNA
188:MVC
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